Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cation-dependent mannose-6-phosphate receptor (Homo sapiens (Human)) | BDBM582015 (WO2023288015, Compound Table12B.770) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2023288015 | n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description M6PR binding was measured in black 96-well plates using a fluorescence polarization assay. A fluorescent probe consisting of a reference M6Pn ligand ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2TX3K67 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cation-dependent mannose-6-phosphate receptor (Homo sapiens (Human)) | BDBM582017 (WO2023288015, Compound Table12B.775) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2023288015 | n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description M6PR binding was measured in black 96-well plates using a fluorescence polarization assay. A fluorescent probe consisting of a reference M6Pn ligand ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2TX3K67 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cation-dependent mannose-6-phosphate receptor (Homo sapiens (Human)) | BDBM582013 (WO2023288015, Compound Table12B.772) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2023288015 | n/a | n/a | 75 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description M6PR binding was measured in black 96-well plates using a fluorescence polarization assay. A fluorescent probe consisting of a reference M6Pn ligand ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2TX3K67 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cation-dependent mannose-6-phosphate receptor (Homo sapiens (Human)) | BDBM582008 (WO2023288015, Compound P5) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2023288015 | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description M6PR binding was measured in black 96-well plates using a fluorescence polarization assay. A fluorescent probe consisting of a reference M6Pn ligand ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2TX3K67 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cation-dependent mannose-6-phosphate receptor (Homo sapiens (Human)) | BDBM582016 (WO2023288015, Compound Table12B.769) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2023288015 | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description M6PR binding was measured in black 96-well plates using a fluorescence polarization assay. A fluorescent probe consisting of a reference M6Pn ligand ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2TX3K67 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cation-dependent mannose-6-phosphate receptor (Homo sapiens (Human)) | BDBM582014 (WO2023288015, Compound Table12B.771) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2023288015 | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description M6PR binding was measured in black 96-well plates using a fluorescence polarization assay. A fluorescent probe consisting of a reference M6Pn ligand ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2TX3K67 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cation-dependent mannose-6-phosphate receptor (Homo sapiens (Human)) | BDBM582012 (WO2023288015, Compound P1) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2023288015 | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description M6PR binding was measured in black 96-well plates using a fluorescence polarization assay. A fluorescent probe consisting of a reference M6Pn ligand ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2TX3K67 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cation-dependent mannose-6-phosphate receptor (Homo sapiens (Human)) | BDBM582011 (WO2023288015, Compound P2) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2023288015 | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description M6PR binding was measured in black 96-well plates using a fluorescence polarization assay. A fluorescent probe consisting of a reference M6Pn ligand ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2TX3K67 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cation-dependent mannose-6-phosphate receptor (Homo sapiens (Human)) | BDBM582010 (WO2023288015, Compound P3) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2023288015 | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description M6PR binding was measured in black 96-well plates using a fluorescence polarization assay. A fluorescent probe consisting of a reference M6Pn ligand ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2TX3K67 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cation-dependent mannose-6-phosphate receptor (Homo sapiens (Human)) | BDBM582007 (WO2023288015, Compound I-68) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2023288015 | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description M6PR binding was measured in black 96-well plates using a fluorescence polarization assay. A fluorescent probe consisting of a reference M6Pn ligand ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2TX3K67 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cation-dependent mannose-6-phosphate receptor (Homo sapiens (Human)) | BDBM582005 (WO2023288015, Compound 38C) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2023288015 | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description M6PR binding was measured in black 96-well plates using a fluorescence polarization assay. A fluorescent probe consisting of a reference M6Pn ligand ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2TX3K67 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cation-dependent mannose-6-phosphate receptor (Homo sapiens (Human)) | BDBM582009 (WO2023288015, Compound P4) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2023288015 | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description M6PR binding was measured in black 96-well plates using a fluorescence polarization assay. A fluorescent probe consisting of a reference M6Pn ligand ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2TX3K67 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cation-dependent mannose-6-phosphate receptor (Homo sapiens (Human)) | BDBM582006 (WO2023288015, Compound I-108) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2023288015 | n/a | n/a | >500 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description M6PR binding was measured in black 96-well plates using a fluorescence polarization assay. A fluorescent probe consisting of a reference M6Pn ligand ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2TX3K67 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cation-dependent mannose-6-phosphate receptor (Homo sapiens (Human)) | BDBM50275808 (CHEMBL470777 | sodium-2-((2R,3S,4S,5S,6S)-3,4,5-tr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 2 et 1 Curated by ChEMBL | Assay Description Binding affinity to CI-M6PR | Bioorg Med Chem Lett 18: 6240-3 (2008) Article DOI: 10.1016/j.bmcl.2008.09.101 BindingDB Entry DOI: 10.7270/Q2WD41HG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cation-dependent mannose-6-phosphate receptor (Homo sapiens (Human)) | BDBM50275807 (mannose 6-phosphate) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 2.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 2 et 1 Curated by ChEMBL | Assay Description Binding affinity to CI-M6PR | Bioorg Med Chem Lett 18: 6240-3 (2008) Article DOI: 10.1016/j.bmcl.2008.09.101 BindingDB Entry DOI: 10.7270/Q2WD41HG | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Cation-dependent mannose-6-phosphate receptor (Homo sapiens (Human)) | BDBM50275809 (CHEMBL470778 | sodium 2-((2R,3S,4S,5S,6S)-3,4,5-tr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 2 et 1 Curated by ChEMBL | Assay Description Binding affinity to CI-M6PR | Bioorg Med Chem Lett 18: 6240-3 (2008) Article DOI: 10.1016/j.bmcl.2008.09.101 BindingDB Entry DOI: 10.7270/Q2WD41HG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cation-dependent mannose-6-phosphate receptor (Homo sapiens (Human)) | BDBM50293267 (CHEMBL469556 | sodium 2-((2R,3S,4S,5S,6S)-3,4,5-tr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 2 et 1 Curated by ChEMBL | Assay Description Binding affinity to CI-M6PR | Bioorg Med Chem Lett 18: 6240-3 (2008) Article DOI: 10.1016/j.bmcl.2008.09.101 BindingDB Entry DOI: 10.7270/Q2WD41HG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cation-dependent mannose-6-phosphate receptor (Homo sapiens (Human)) | BDBM50293266 (CHEMBL510805 | mannose 6-sulfonate) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.30E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 2 et 1 Curated by ChEMBL | Assay Description Binding affinity to CI-M6PR | Bioorg Med Chem Lett 18: 6240-3 (2008) Article DOI: 10.1016/j.bmcl.2008.09.101 BindingDB Entry DOI: 10.7270/Q2WD41HG | |||||||||||
More data for this Ligand-Target Pair |