Compile Data Set for Download or QSAR

Found 46 hits Enz. Inhib. hit(s) with Target = 'Cytochrome P450 11B1, mitochondrial' AND taxid = 10116   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B1, mitochondrial (Rattus norvegicus)	BDBM50444550 (CHEMBL3099704) Show SMILES Fc1ccc(cc1)-c1cc(ccc1[C@H]1CCCCc2cncn12)C#N |r| Show InChI InChI=1S/C21H18FN3/c22-17-8-6-16(7-9-17)20-11-15(12-23)5-10-19(20)21-4-2-1-3-18-13-24-14-25(18)21/h5-11,13-14,21H,1-4H2/t21-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of rat recombinant CYP11B1 using 11-deoxycortisol as substrate by cell-based assay				ACS Med Chem Lett 4: 1203-7 (2013) Article DOI: 10.1021/ml400324c BindingDB Entry DOI: 10.7270/Q2NZ8938
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Rattus norvegicus)	BDBM50595569 (CHEMBL5184829) Show SMILES [H][C@@]12CC[C@@]([H])(C1)[C@]1(ON=C(c3cccnc3)[C@@]21[H])C(=O)Nc1ccc2[nH]ncc2c1 |r,t:10| Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01037 BindingDB Entry DOI: 10.7270/Q2SN0DZT
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Rattus norvegicus)	BDBM50082277 (CHEMBL3421769) Show SMILES [O-][N+](=O)c1ccc(c(OCCc2ccccc2)c1)-c1ccncc1 Show InChI InChI=1S/C19H16N2O3/c22-21(23)17-6-7-18(16-8-11-20-12-9-16)19(14-17)24-13-10-15-4-2-1-3-5-15/h1-9,11-12,14H,10,13H2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	163	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of rat CYP11B1 expressed in hamster fibroblast using 500 nM [3H]-11-deoxycorticosterone as substrate after 7 hrs by HPLC analysis				Eur J Med Chem 96: 139-50 (2015) Article DOI: 10.1016/j.ejmech.2015.04.013 BindingDB Entry DOI: 10.7270/Q2WQ05HQ
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Rattus norvegicus)	BDBM50082276 (CHEMBL3421770) Show SMILES [O-][N+](=O)c1ccc(c(OCCCc2ccccc2)c1)-c1ccncc1 Show InChI InChI=1S/C20H18N2O3/c23-22(24)18-8-9-19(17-10-12-21-13-11-17)20(15-18)25-14-4-7-16-5-2-1-3-6-16/h1-3,5-6,8-13,15H,4,7,14H2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of rat CYP11B1 expressed in hamster fibroblast using 500 nM [3H]-11-deoxycorticosterone as substrate after 7 hrs by HPLC analysis				Eur J Med Chem 96: 139-50 (2015) Article DOI: 10.1016/j.ejmech.2015.04.013 BindingDB Entry DOI: 10.7270/Q2WQ05HQ
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Rattus norvegicus)	BDBM50444548 (CHEMBL3099696) Show SMILES Cc1cc(ccc1[C@H]1CCc2cncn12)C#N |r| Show InChI InChI=1S/C14H13N3/c1-10-6-11(7-15)2-4-13(10)14-5-3-12-8-16-9-17(12)14/h2,4,6,8-9,14H,3,5H2,1H3/t14-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	386	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of rat recombinant CYP11B1 using 11-deoxycortisol as substrate by cell-based assay				ACS Med Chem Lett 4: 1203-7 (2013) Article DOI: 10.1021/ml400324c BindingDB Entry DOI: 10.7270/Q2NZ8938
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Rattus norvegicus)	BDBM50082288 (CHEMBL3421780) Show SMILES N#Cc1ccc(c(OCCc2ccccc2)c1)-c1ccncc1 Show InChI InChI=1S/C20H16N2O/c21-15-17-6-7-19(18-8-11-22-12-9-18)20(14-17)23-13-10-16-4-2-1-3-5-16/h1-9,11-12,14H,10,13H2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	441	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of rat CYP11B1 expressed in hamster fibroblast using 500 nM [3H]-11-deoxycorticosterone as substrate after 7 hrs by HPLC analysis				Eur J Med Chem 96: 139-50 (2015) Article DOI: 10.1016/j.ejmech.2015.04.013 BindingDB Entry DOI: 10.7270/Q2WQ05HQ
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Rattus norvegicus)	BDBM50444549 (CHEMBL3099695) Show SMILES Fc1cc(ccc1[C@H]1CCc2cncn12)C#N |r| Show InChI InChI=1S/C13H10FN3/c14-12-5-9(6-15)1-3-11(12)13-4-2-10-7-16-8-17(10)13/h1,3,5,7-8,13H,2,4H2/t13-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	495	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of rat recombinant CYP11B1 using 11-deoxycortisol as substrate by cell-based assay				ACS Med Chem Lett 4: 1203-7 (2013) Article DOI: 10.1021/ml400324c BindingDB Entry DOI: 10.7270/Q2NZ8938
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Rattus norvegicus)	BDBM50082287 (CHEMBL3421779) Show SMILES N#Cc1ccc(c(OCCc2ccccc2)c1)-c1cccnc1 Show InChI InChI=1S/C20H16N2O/c21-14-17-8-9-19(18-7-4-11-22-15-18)20(13-17)23-12-10-16-5-2-1-3-6-16/h1-9,11,13,15H,10,12H2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	543	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of rat CYP11B1 expressed in hamster fibroblast using 500 nM [3H]-11-deoxycorticosterone as substrate after 7 hrs by HPLC analysis				Eur J Med Chem 96: 139-50 (2015) Article DOI: 10.1016/j.ejmech.2015.04.013 BindingDB Entry DOI: 10.7270/Q2WQ05HQ
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Rattus norvegicus)	BDBM50082278 (CHEMBL3421768) Show SMILES [O-][N+](=O)c1ccc(c(OCc2ccccc2)c1)-c1ccncc1 Show InChI InChI=1S/C18H14N2O3/c21-20(22)16-6-7-17(15-8-10-19-11-9-15)18(12-16)23-13-14-4-2-1-3-5-14/h1-12H,13H2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	648	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of rat CYP11B1 expressed in hamster fibroblast using 500 nM [3H]-11-deoxycorticosterone as substrate after 7 hrs by HPLC analysis				Eur J Med Chem 96: 139-50 (2015) Article DOI: 10.1016/j.ejmech.2015.04.013 BindingDB Entry DOI: 10.7270/Q2WQ05HQ
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Rattus norvegicus)	BDBM50047262 ((R)-4-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-y...) Show SMILES N#Cc1ccc(cc1)[C@H]1CCCc2cncn12 Show InChI InChI=1S/C14H13N3/c15-8-11-4-6-12(7-5-11)14-3-1-2-13-9-16-10-17(13)14/h4-7,9-10,14H,1-3H2/t14-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	686	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of rat recombinant CYP11B1 using 11-deoxycortisol as substrate by cell-based assay				ACS Med Chem Lett 4: 1203-7 (2013) Article DOI: 10.1021/ml400324c BindingDB Entry DOI: 10.7270/Q2NZ8938
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Rattus norvegicus)	BDBM50082293 (CHEMBL3421785) Show SMILES [O-][N+](=O)c1ccc(Cc2cccnc2)c(OCCc2ccccc2)c1 Show InChI InChI=1S/C20H18N2O3/c23-22(24)19-9-8-18(13-17-7-4-11-21-15-17)20(14-19)25-12-10-16-5-2-1-3-6-16/h1-9,11,14-15H,10,12-13H2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	706	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of rat CYP11B1 expressed in hamster fibroblast using 500 nM [3H]-11-deoxycorticosterone as substrate after 7 hrs by HPLC analysis				Eur J Med Chem 96: 139-50 (2015) Article DOI: 10.1016/j.ejmech.2015.04.013 BindingDB Entry DOI: 10.7270/Q2WQ05HQ
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Rattus norvegicus)	BDBM8611 (4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonit...) Show SMILES N#Cc1ccc(cc1)C1CCCc2cncn12 Show InChI InChI=1S/C14H13N3/c15-8-11-4-6-12(7-5-11)14-3-1-2-13-9-16-10-17(13)14/h4-7,9-10,14H,1-3H2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by ChEMBL					Assay Description Inhibition of ACTH-stimulated aldosterone production in rat adrenal tissue				J Med Chem 34: 725-36 (1991) BindingDB Entry DOI: 10.7270/Q2SB46BP
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Rattus norvegicus)	BDBM50082280 (CHEMBL3421766) Show SMILES [O-][N+](=O)c1ccc(c(OCCc2ccccc2)c1)-c1cccnc1 Show InChI InChI=1S/C19H16N2O3/c22-21(23)17-8-9-18(16-7-4-11-20-14-16)19(13-17)24-12-10-15-5-2-1-3-6-15/h1-9,11,13-14H,10,12H2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.31E+3	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of rat CYP11B1 expressed in hamster fibroblast using 500 nM [3H]-11-deoxycorticosterone as substrate after 7 hrs by HPLC analysis				Eur J Med Chem 96: 139-50 (2015) Article DOI: 10.1016/j.ejmech.2015.04.013 BindingDB Entry DOI: 10.7270/Q2WQ05HQ
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Rattus norvegicus)	BDBM50082281 (CHEMBL3421765) Show SMILES [O-][N+](=O)c1ccc(c(OCc2ccccc2)c1)-c1cccnc1 Show InChI InChI=1S/C18H14N2O3/c21-20(22)16-8-9-17(15-7-4-10-19-12-15)18(11-16)23-13-14-5-2-1-3-6-14/h1-12H,13H2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.49E+3	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of rat CYP11B1 expressed in hamster fibroblast using 500 nM [3H]-11-deoxycorticosterone as substrate after 7 hrs by HPLC analysis				Eur J Med Chem 96: 139-50 (2015) Article DOI: 10.1016/j.ejmech.2015.04.013 BindingDB Entry DOI: 10.7270/Q2WQ05HQ
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Rattus norvegicus)	BDBM50395609 (CHEMBL2165320) Show SMILES O=C1CCc2cc(c(OCc3ccccc3)cc2N1)-c1cccnc1 Show InChI InChI=1S/C21H18N2O2/c24-21-9-8-16-11-18(17-7-4-10-22-13-17)20(12-19(16)23-21)25-14-15-5-2-1-3-6-15/h1-7,10-13H,8-9,14H2,(H,23,24)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of rat CYP11B1 expressed in hamster fibroblast using 500 nM [3H]-11-deoxycorticosterone as substrate after 7 hrs by HPLC analysis				Eur J Med Chem 96: 139-50 (2015) Article DOI: 10.1016/j.ejmech.2015.04.013 BindingDB Entry DOI: 10.7270/Q2WQ05HQ
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Rattus norvegicus)	BDBM50239789 (CHEMBL4097298) Show SMILES COc1cncc(Cc2cc(no2)-c2ccccc2)c1 Show InChI InChI=1S/C16H14N2O2/c1-19-15-8-12(10-17-11-15)7-14-9-16(18-20-14)13-5-3-2-4-6-13/h2-6,8-11H,7H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of rat CYP11B1 expressed in hamster V79MZ cells using [1,2-3H]-11-deoxycorticosterone as substrate after 6 hrs by HPLC analysis				J Med Chem 60: 5086-5098 (2017) Article DOI: 10.1021/acs.jmedchem.7b00437 BindingDB Entry DOI: 10.7270/Q24F1SWW
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Rattus norvegicus)	BDBM50022121 (3-Imidazol-1-ylmethyl-2-isopropyl-1H-indole | 3-Im...) Show SMILES CC(C)c1[nH]c2ccccc2c1Cn1ccnc1 Show InChI InChI=1S/C15H17N3/c1-11(2)15-13(9-18-8-7-16-10-18)12-5-3-4-6-14(12)17-15/h3-8,10-11,17H,9H2,1-2H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of rat adrenal 11-beta-hydroxylase				J Med Chem 28: 1427-32 (1985) BindingDB Entry DOI: 10.7270/Q2DJ5DN7
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Rattus norvegicus)	BDBM50022121 (3-Imidazol-1-ylmethyl-2-isopropyl-1H-indole | 3-Im...) Show SMILES CC(C)c1[nH]c2ccccc2c1Cn1ccnc1 Show InChI InChI=1S/C15H17N3/c1-11(2)15-13(9-18-8-7-16-10-18)12-5-3-4-6-14(12)17-15/h3-8,10-11,17H,9H2,1-2H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of 11 beta-hydroxylase from rat adrenal gland				J Med Chem 29: 342-6 (1986) BindingDB Entry DOI: 10.7270/Q2W66JSZ
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Rattus norvegicus)	BDBM50082279 (CHEMBL3421767) Show SMILES [O-][N+](=O)c1ccc(c(OCCCc2ccccc2)c1)-c1cccnc1 Show InChI InChI=1S/C20H18N2O3/c23-22(24)18-10-11-19(17-9-4-12-21-15-17)20(14-18)25-13-5-8-16-6-2-1-3-7-16/h1-4,6-7,9-12,14-15H,5,8,13H2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.08E+3	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of rat CYP11B1 expressed in hamster fibroblast using 500 nM [3H]-11-deoxycorticosterone as substrate after 7 hrs by HPLC analysis				Eur J Med Chem 96: 139-50 (2015) Article DOI: 10.1016/j.ejmech.2015.04.013 BindingDB Entry DOI: 10.7270/Q2WQ05HQ
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Rattus norvegicus)	BDBM50439057 (CHEMBL2417553) Show SMILES Cc1cncc(Cc2ccc(nc2)-c2ccccc2)c1 Show InChI InChI=1S/C18H16N2/c1-14-9-16(12-19-11-14)10-15-7-8-18(20-13-15)17-5-3-2-4-6-17/h2-9,11-13H,10H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.44E+3	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of rat CYP11B1 expressed in hamster fibroblast using 500 nM [3H]-11-deoxycorticosterone as substrate after 7 hrs by HPLC analysis				Eur J Med Chem 96: 139-50 (2015) Article DOI: 10.1016/j.ejmech.2015.04.013 BindingDB Entry DOI: 10.7270/Q2WQ05HQ
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Rattus norvegicus)	BDBM50439057 (CHEMBL2417553) Show SMILES Cc1cncc(Cc2ccc(nc2)-c2ccccc2)c1 Show InChI InChI=1S/C18H16N2/c1-14-9-16(12-19-11-14)10-15-7-8-18(20-13-15)17-5-3-2-4-6-17/h2-9,11-13H,10H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.44E+3	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of rat CYP11B1 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxycorticosterone as substrate				J Med Chem 56: 6022-32 (2013) Article DOI: 10.1021/jm400240r BindingDB Entry DOI: 10.7270/Q20866QJ
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Rattus norvegicus)	BDBM50082294 (CHEMBL3421786) Show SMILES [O-][N+](=O)c1ccc(Cc2ccncc2)c(OCCc2ccccc2)c1 Show InChI InChI=1S/C20H18N2O3/c23-22(24)19-7-6-18(14-17-8-11-21-12-9-17)20(15-19)25-13-10-16-4-2-1-3-5-16/h1-9,11-12,15H,10,13-14H2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.85E+3	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of rat CYP11B1 expressed in hamster fibroblast using 500 nM [3H]-11-deoxycorticosterone as substrate after 7 hrs by HPLC analysis				Eur J Med Chem 96: 139-50 (2015) Article DOI: 10.1016/j.ejmech.2015.04.013 BindingDB Entry DOI: 10.7270/Q2WQ05HQ
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Rattus norvegicus)	BDBM50239790 (CHEMBL4079276) Show SMILES Cc1cncc(Cc2cc(no2)-c2ccccc2)c1 Show InChI InChI=1S/C16H14N2O/c1-12-7-13(11-17-10-12)8-15-9-16(18-19-15)14-5-3-2-4-6-14/h2-7,9-11H,8H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of rat CYP11B1 expressed in hamster V79MZ cells using [1,2-3H]-11-deoxycorticosterone as substrate after 6 hrs by HPLC analysis				J Med Chem 60: 5086-5098 (2017) Article DOI: 10.1021/acs.jmedchem.7b00437 BindingDB Entry DOI: 10.7270/Q24F1SWW
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Rattus norvegicus)	BDBM50028166 (CHEMBL934 | METYRAPONE | US9138393, Metyrapone | U...) Show SMILES CC(C)(C(=O)c1cccnc1)c1cccnc1 Show InChI InChI=1S/C14H14N2O/c1-14(2,12-6-4-8-16-10-12)13(17)11-5-3-7-15-9-11/h3-10H,1-2H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of rat CYP11B1 expressed in hamster V79MZ cells using [1,2-3H]-11-deoxycorticosterone as substrate after 6 hrs by HPLC analysis				J Med Chem 60: 5086-5098 (2017) Article DOI: 10.1021/acs.jmedchem.7b00437 BindingDB Entry DOI: 10.7270/Q24F1SWW
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Rattus norvegicus)	BDBM50028166 (CHEMBL934 | METYRAPONE | US9138393, Metyrapone | U...) Show SMILES CC(C)(C(=O)c1cccnc1)c1cccnc1 Show InChI InChI=1S/C14H14N2O/c1-14(2,12-6-4-8-16-10-12)13(17)11-5-3-7-15-9-11/h3-10H,1-2H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	4.61E+3	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of rat CYP11B1 expressed in hamster fibroblast using 500 nM [3H]-11-deoxycorticosterone as substrate after 7 hrs by HPLC analysis				Eur J Med Chem 96: 139-50 (2015) Article DOI: 10.1016/j.ejmech.2015.04.013 BindingDB Entry DOI: 10.7270/Q2WQ05HQ
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Rattus norvegicus)	BDBM50028166 (CHEMBL934 | METYRAPONE | US9138393, Metyrapone | U...) Show SMILES CC(C)(C(=O)c1cccnc1)c1cccnc1 Show InChI InChI=1S/C14H14N2O/c1-14(2,12-6-4-8-16-10-12)13(17)11-5-3-7-15-9-11/h3-10H,1-2H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of CYP11B1 in Sprague-Dawley rat adrenal tissue using 11-deoxycorticosterone as substrate after 4 hrs by SPA				J Med Chem 60: 5086-5098 (2017) Article DOI: 10.1021/acs.jmedchem.7b00437 BindingDB Entry DOI: 10.7270/Q24F1SWW
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Rattus norvegicus)	BDBM50022120 (3-Imidazol-1-ylmethyl-1H-indole | CHEMBL116794) Show SMILES C(c1c[nH]c2ccccc12)n1ccnc1 Show InChI InChI=1S/C12H11N3/c1-2-4-12-11(3-1)10(7-14-12)8-15-6-5-13-9-15/h1-7,9,14H,8H2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of 11 beta-hydroxylase from rat adrenal gland				J Med Chem 29: 342-6 (1986) BindingDB Entry DOI: 10.7270/Q2W66JSZ
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Rattus norvegicus)	BDBM50022118 (3-(3-Imidazol-1-ylmethyl-2-isopropyl-indol-1-yl)-p...) Show SMILES CC(C)c1c(Cn2ccnc2)c2ccccc2n1CCC(O)=O Show InChI InChI=1S/C18H21N3O2/c1-13(2)18-15(11-20-10-8-19-12-20)14-5-3-4-6-16(14)21(18)9-7-17(22)23/h3-6,8,10,12-13H,7,9,11H2,1-2H3,(H,22,23)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of 11 beta-hydroxylase from rat adrenal gland				J Med Chem 29: 342-6 (1986) BindingDB Entry DOI: 10.7270/Q2W66JSZ
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Rattus norvegicus)	BDBM50022117 (1-Ethyl-3-imidazol-1-ylmethyl-1H-indole | CHEMBL11...) Show SMILES CCn1cc(Cn2ccnc2)c2ccccc12 Show InChI InChI=1S/C14H15N3/c1-2-17-10-12(9-16-8-7-15-11-16)13-5-3-4-6-14(13)17/h3-8,10-11H,2,9H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of 11 beta-hydroxylase from rat adrenal gland				J Med Chem 29: 342-6 (1986) BindingDB Entry DOI: 10.7270/Q2W66JSZ
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Rattus norvegicus)	BDBM50335360 (5-((1H-imidazol-1-yl)methyl)-2-phenylpyridine | CH...) Show SMILES C(c1ccc(nc1)-c1ccccc1)n1ccnc1 Show InChI InChI=1S/C15H13N3/c1-2-4-14(5-3-1)15-7-6-13(10-17-15)11-18-9-8-16-12-18/h1-10,12H,11H2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of rat CYP11B1 expressed in hamster fibroblast using 500 nM [3H]-11-deoxycorticosterone as substrate after 7 hrs by HPLC analysis				Eur J Med Chem 96: 139-50 (2015) Article DOI: 10.1016/j.ejmech.2015.04.013 BindingDB Entry DOI: 10.7270/Q2WQ05HQ
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Rattus norvegicus)	BDBM50025995 (4-(2-Imidazol-1-yl-ethoxy)-benzamide | CHEMBL30395) Show SMILES NC(=O)c1ccc(OCCn2ccnc2)cc1 Show InChI InChI=1S/C12H13N3O2/c13-12(16)10-1-3-11(4-2-10)17-8-7-15-6-5-14-9-15/h1-6,9H,7-8H2,(H2,13,16)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of rat adrenal 11-beta-hydroxylase				J Med Chem 28: 1427-32 (1985) BindingDB Entry DOI: 10.7270/Q2DJ5DN7
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Rattus norvegicus)	BDBM50022217 (2-Imidazol-1-ylmethyl-benzo[b]thiophene-5-carboxyl...) Show SMILES OC(=O)c1ccc2sc(Cn3ccnc3)cc2c1 Show InChI InChI=1S/C13H10N2O2S/c16-13(17)9-1-2-12-10(5-9)6-11(18-12)7-15-4-3-14-8-15/h1-6,8H,7H2,(H,16,17)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of rat adrenal 11-beta-hydroxylase				J Med Chem 29: 1643-50 (1986) BindingDB Entry DOI: 10.7270/Q2C8289W
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Rattus norvegicus)	BDBM50022230 (3-Bromo-2-imidazol-1-ylmethyl-benzo[b]thiophene-5-...) Show SMILES OC(=O)c1ccc2sc(Cn3ccnc3)c(Br)c2c1 Show InChI InChI=1S/C13H9BrN2O2S/c14-12-9-5-8(13(17)18)1-2-10(9)19-11(12)6-16-4-3-15-7-16/h1-5,7H,6H2,(H,17,18)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of rat adrenal 11-beta-hydroxylase				J Med Chem 29: 1643-50 (1986) BindingDB Entry DOI: 10.7270/Q2C8289W
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Rattus norvegicus)	BDBM50022223 (3-Chloro-2-imidazol-1-ylmethyl-benzofuran-5-carbox...) Show SMILES OC(=O)c1ccc2oc(Cn3ccnc3)c(Cl)c2c1 Show InChI InChI=1S/C13H9ClN2O3/c14-12-9-5-8(13(17)18)1-2-10(9)19-11(12)6-16-4-3-15-7-16/h1-5,7H,6H2,(H,17,18)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of rat adrenal 11-beta-hydroxylase				J Med Chem 29: 1643-50 (1986) BindingDB Entry DOI: 10.7270/Q2C8289W
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Rattus norvegicus)	BDBM50022226 (6-Imidazol-1-ylmethyl-5-methyl-naphthalene-1-carbo...) Show SMILES Cc1c(Cn2ccnc2)ccc2c(cccc12)C(O)=O Show InChI InChI=1S/C16H14N2O2/c1-11-12(9-18-8-7-17-10-18)5-6-14-13(11)3-2-4-15(14)16(19)20/h2-8,10H,9H2,1H3,(H,19,20)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of rat adrenal 11-beta-hydroxylase				J Med Chem 29: 1643-50 (1986) BindingDB Entry DOI: 10.7270/Q2C8289W
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Rattus norvegicus)	BDBM50022216 (2-Imidazol-1-ylmethyl-3-methyl-benzo[b]thiophene-5...) Show SMILES Cc1c(Cn2ccnc2)sc2ccc(cc12)C(O)=O Show InChI InChI=1S/C14H12N2O2S/c1-9-11-6-10(14(17)18)2-3-12(11)19-13(9)7-16-5-4-15-8-16/h2-6,8H,7H2,1H3,(H,17,18)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of rat adrenal 11-beta-hydroxylase				J Med Chem 29: 1643-50 (1986) BindingDB Entry DOI: 10.7270/Q2C8289W
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Rattus norvegicus)	BDBM8611 (4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonit...) Show SMILES N#Cc1ccc(cc1)C1CCCc2cncn12 Show InChI InChI=1S/C14H13N3/c15-8-11-4-6-12(7-5-11)14-3-1-2-13-9-16-10-17(13)14/h4-7,9-10,14H,1-3H2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by ChEMBL					Assay Description Inhibition of ACTH-stimulated corticosterone production in rat adrenal tissue				J Med Chem 34: 725-36 (1991) BindingDB Entry DOI: 10.7270/Q2SB46BP
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Rattus norvegicus)	BDBM50000317 (3-(3-Imidazol-1-ylmethyl-2-methyl-indol-1-yl)-prop...) Show SMILES Cc1c(Cn2ccnc2)c2ccccc2n1CCC(O)=O Show InChI InChI=1S/C16H17N3O2/c1-12-14(10-18-9-7-17-11-18)13-4-2-3-5-15(13)19(12)8-6-16(20)21/h2-5,7,9,11H,6,8,10H2,1H3,(H,20,21)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of 11 beta-hydroxylase from rat adrenal gland				J Med Chem 29: 342-6 (1986) BindingDB Entry DOI: 10.7270/Q2W66JSZ
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Rattus norvegicus)	BDBM50022124 (3-(3-Imidazol-1-ylmethyl-indol-1-yl)-propionic aci...) Show SMILES OC(=O)CCn1cc(Cn2ccnc2)c2ccccc12 Show InChI InChI=1S/C15H15N3O2/c19-15(20)5-7-18-10-12(9-17-8-6-16-11-17)13-3-1-2-4-14(13)18/h1-4,6,8,10-11H,5,7,9H2,(H,19,20)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of 11 beta-hydroxylase from rat adrenal gland				J Med Chem 29: 342-6 (1986) BindingDB Entry DOI: 10.7270/Q2W66JSZ
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Rattus norvegicus)	BDBM7962 (4-(2-Imidazol-1-yl-ethoxy)-benzoic acid; hydrochlo...) Show SMILES OC(=O)c1ccc(OCCn2ccnc2)cc1 Show InChI InChI=1S/C12H12N2O3/c15-12(16)10-1-3-11(4-2-10)17-8-7-14-6-5-13-9-14/h1-6,9H,7-8H2,(H,15,16)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of 11 beta-hydroxylase from rat adrenal gland				J Med Chem 29: 342-6 (1986) BindingDB Entry DOI: 10.7270/Q2W66JSZ
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Rattus norvegicus)	BDBM50022222 (2-Imidazol-1-ylmethyl-3-methyl-benzofuran-5-carbox...) Show SMILES Cc1c(Cn2ccnc2)oc2ccc(cc12)C(O)=O Show InChI InChI=1S/C14H12N2O3/c1-9-11-6-10(14(17)18)2-3-12(11)19-13(9)7-16-5-4-15-8-16/h2-6,8H,7H2,1H3,(H,17,18)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of rat adrenal 11-beta-hydroxylase				J Med Chem 29: 1643-50 (1986) BindingDB Entry DOI: 10.7270/Q2C8289W
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Rattus norvegicus)	BDBM7962 (4-(2-Imidazol-1-yl-ethoxy)-benzoic acid; hydrochlo...) Show SMILES OC(=O)c1ccc(OCCn2ccnc2)cc1 Show InChI InChI=1S/C12H12N2O3/c15-12(16)10-1-3-11(4-2-10)17-8-7-14-6-5-13-9-14/h1-6,9H,7-8H2,(H,15,16)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of rat adrenal 11-beta-hydroxylase				J Med Chem 29: 1643-50 (1986) BindingDB Entry DOI: 10.7270/Q2C8289W
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Rattus norvegicus)	BDBM50025983 (CHEMBL34041 | [4-(2-Imidazol-1-yl-ethoxy)-phenoxy]...) Show SMILES OC(=O)COc1ccc(OCCn2ccnc2)cc1 Show InChI InChI=1S/C13H14N2O4/c16-13(17)9-19-12-3-1-11(2-4-12)18-8-7-15-6-5-14-10-15/h1-6,10H,7-9H2,(H,16,17)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of rat adrenal 11-beta-hydroxylase				J Med Chem 28: 1427-32 (1985) BindingDB Entry DOI: 10.7270/Q2DJ5DN7
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Rattus norvegicus)	BDBM50026000 (3-(2-Imidazol-1-yl-ethoxy)-benzoic acid | CHEMBL33...) Show SMILES OC(=O)c1cccc(OCCn2ccnc2)c1 Show InChI InChI=1S/C12H12N2O3/c15-12(16)10-2-1-3-11(8-10)17-7-6-14-5-4-13-9-14/h1-5,8-9H,6-7H2,(H,15,16)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of rat adrenal 11-beta-hydroxylase				J Med Chem 28: 1427-32 (1985) BindingDB Entry DOI: 10.7270/Q2DJ5DN7
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Rattus norvegicus)	BDBM50026004 (2-[4-(2-Imidazol-1-yl-ethoxy)-phenoxy]-acetamide |...) Show SMILES NC(=O)COc1ccc(OCCn2ccnc2)cc1 Show InChI InChI=1S/C13H15N3O3/c14-13(17)9-19-12-3-1-11(2-4-12)18-8-7-16-6-5-15-10-16/h1-6,10H,7-9H2,(H2,14,17)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of rat adrenal 11-beta-hydroxylase				J Med Chem 28: 1427-32 (1985) BindingDB Entry DOI: 10.7270/Q2DJ5DN7
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Rattus norvegicus)	BDBM7962 (4-(2-Imidazol-1-yl-ethoxy)-benzoic acid; hydrochlo...) Show SMILES OC(=O)c1ccc(OCCn2ccnc2)cc1 Show InChI InChI=1S/C12H12N2O3/c15-12(16)10-1-3-11(4-2-10)17-8-7-14-6-5-13-9-14/h1-6,9H,7-8H2,(H,15,16)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of rat adrenal 11-beta-hydroxylase				J Med Chem 28: 1427-32 (1985) BindingDB Entry DOI: 10.7270/Q2DJ5DN7
					More data for this Ligand-Target Pair