Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
D-alanyl-D-alanine dipeptidase (Enterococcus faecium) | BDBM50014155 (CHEMBL3260854) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description Inhibition of Enterococcus faecium VanX expressed in Escherichia coli BL21 (DE3) cells using D-alanyl-alpha-R-phenylthioglycine as substrate by color... | Bioorg Med Chem Lett 24: 2535-8 (2014) Article DOI: 10.1016/j.bmcl.2014.03.097 BindingDB Entry DOI: 10.7270/Q2B56M96 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanyl-D-alanine dipeptidase (Enterococcus faecium) | BDBM50014161 (CHEMBL3260858 | US11491146, Compound 5) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.74E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description Inhibition of Enterococcus faecium VanX expressed in Escherichia coli BL21 (DE3) cells using D-alanyl-alpha-R-phenylthioglycine as substrate by color... | Bioorg Med Chem Lett 24: 2535-8 (2014) Article DOI: 10.1016/j.bmcl.2014.03.097 BindingDB Entry DOI: 10.7270/Q2B56M96 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanyl-D-alanine dipeptidase (Enterococcus faecium) | BDBM50014157 (CHEMBL3260855) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description Inhibition of Enterococcus faecium VanX expressed in Escherichia coli BL21 (DE3) cells using D-alanyl-alpha-R-phenylthioglycine as substrate by color... | Bioorg Med Chem Lett 24: 2535-8 (2014) Article DOI: 10.1016/j.bmcl.2014.03.097 BindingDB Entry DOI: 10.7270/Q2B56M96 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanyl-D-alanine dipeptidase (Enterococcus faecium) | BDBM50014158 (CHEMBL3260856) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 6.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description Inhibition of Enterococcus faecium VanX expressed in Escherichia coli BL21 (DE3) cells using D-alanyl-alpha-R-phenylthioglycine as substrate by color... | Bioorg Med Chem Lett 24: 2535-8 (2014) Article DOI: 10.1016/j.bmcl.2014.03.097 BindingDB Entry DOI: 10.7270/Q2B56M96 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanyl-D-alanine dipeptidase (Enterococcus faecium) | BDBM50014160 (CHEMBL3260857) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 6.84E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description Inhibition of Enterococcus faecium VanX expressed in Escherichia coli BL21 (DE3) cells using D-alanyl-alpha-R-phenylthioglycine as substrate by color... | Bioorg Med Chem Lett 24: 2535-8 (2014) Article DOI: 10.1016/j.bmcl.2014.03.097 BindingDB Entry DOI: 10.7270/Q2B56M96 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanyl-D-alanine dipeptidase (Enterococcus faecium) | BDBM50335519 ((S)-3,6-Diamino-hexanoic acid {(3S,9S,12S,15S)-3-(...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars | DrugBank Article PubMed | 6.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance, Inc. Curated by ChEMBL | Assay Description Inhibition of D,D-dipeptidase activity Van X in Enterococcus faecium ATCC 51559 using D-alanyl-(R)-phenylthioglycine substrate | Antimicrob Agents Chemother 54: 2814-8 (2010) Article DOI: 10.1128/AAC.01737-09 BindingDB Entry DOI: 10.7270/Q2TB1751 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanyl-D-alanine dipeptidase (Enterococcus faecium) | BDBM50361935 (CHEMBL1939351) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.80E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwest University Curated by ChEMBL | Assay Description Inhibition of Enterococcus faecium VanX overexpressed in Escherichia coli BL21 (DE3) cells using D-ala-D-ala as substrate preincubated for 3 mins mea... | Bioorg Med Chem Lett 22: 482-4 (2011) Article DOI: 10.1016/j.bmcl.2011.10.094 BindingDB Entry DOI: 10.7270/Q25D8S8F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanyl-D-alanine dipeptidase (Enterococcus faecium) | BDBM50361940 (CHEMBL1939352) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.60E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwest University Curated by ChEMBL | Assay Description Competitive inhibition of Enterococcus faecium VanX overexpressed in Escherichia coli BL21 (DE3) cells using D-ala-D-ala as substrate preincubated fo... | Bioorg Med Chem Lett 22: 482-4 (2011) Article DOI: 10.1016/j.bmcl.2011.10.094 BindingDB Entry DOI: 10.7270/Q25D8S8F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanyl-D-alanine dipeptidase (Enterococcus faecium) | BDBM50361937 (CHEMBL1939354) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.08E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwest University Curated by ChEMBL | Assay Description Inhibition of Enterococcus faecium VanX overexpressed in Escherichia coli BL21 (DE3) cells using D-ala-D-ala as substrate preincubated for 3 mins mea... | Bioorg Med Chem Lett 22: 482-4 (2011) Article DOI: 10.1016/j.bmcl.2011.10.094 BindingDB Entry DOI: 10.7270/Q25D8S8F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanyl-D-alanine dipeptidase (Enterococcus faecium) | BDBM50361938 (CHEMBL1939355) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.31E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwest University Curated by ChEMBL | Assay Description Inhibition of Enterococcus faecium VanX overexpressed in Escherichia coli BL21 (DE3) cells using D-ala-D-ala as substrate preincubated for 3 mins mea... | Bioorg Med Chem Lett 22: 482-4 (2011) Article DOI: 10.1016/j.bmcl.2011.10.094 BindingDB Entry DOI: 10.7270/Q25D8S8F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanyl-D-alanine dipeptidase (Enterococcus faecium) | BDBM50361936 (CHEMBL1939353) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.82E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwest University Curated by ChEMBL | Assay Description Inhibition of Enterococcus faecium VanX overexpressed in Escherichia coli BL21 (DE3) cells using D-ala-D-ala as substrate preincubated for 3 mins mea... | Bioorg Med Chem Lett 22: 482-4 (2011) Article DOI: 10.1016/j.bmcl.2011.10.094 BindingDB Entry DOI: 10.7270/Q25D8S8F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanyl-D-alanine dipeptidase (Enterococcus faecium) | BDBM50361939 (CHEMBL1939356) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8.21E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwest University Curated by ChEMBL | Assay Description Inhibition of Enterococcus faecium VanX overexpressed in Escherichia coli BL21 (DE3) cells using D-ala-D-ala as substrate preincubated for 3 mins mea... | Bioorg Med Chem Lett 22: 482-4 (2011) Article DOI: 10.1016/j.bmcl.2011.10.094 BindingDB Entry DOI: 10.7270/Q25D8S8F | |||||||||||
More data for this Ligand-Target Pair |