Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
DNA polymerase delta catalytic subunit (Homo sapiens (Human)) | BDBM50370476 (Combivir | ZIDOVUDINE TRIPHOSPHATE) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Pharmacia Corporation Curated by ChEMBL | Assay Description Inhibition of human delta DNA polymerase (95 uL) activity in a solution containg 6.4 mM HEPES (pH 7.5) upon incubation for 12 minutes at 26 degrees C... | J Med Chem 48: 5794-804 (2005) Article DOI: 10.1021/jm050162b BindingDB Entry DOI: 10.7270/Q2G44R39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase delta catalytic subunit (Homo sapiens (Human)) | BDBM50011181 ((PFA)dihydroxyphosphinecarboxylic acid oxide | CHE...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Pharmacia Corporation Curated by ChEMBL | Assay Description Inhibition of human delta DNA polymerase (95 uL) activity in a solution containg 6.4 mM HEPES (pH 7.5) upon incubation for 12 minutes at 26 degrees C... | J Med Chem 48: 5794-804 (2005) Article DOI: 10.1021/jm050162b BindingDB Entry DOI: 10.7270/Q2G44R39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase delta catalytic subunit (Homo sapiens (Human)) | BDBM50172526 (1-Methyl-6-morpholin-4-ylmethyl-4-oxo-1,4-dihydro-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Pharmacia Corporation Curated by ChEMBL | Assay Description Inhibition of human delta DNA polymerase (95 uL) activity in a solution containg 6.4 mM HEPES (pH 7.5) upon incubation for 12 minutes at 26 degrees C... | J Med Chem 48: 5794-804 (2005) Article DOI: 10.1021/jm050162b BindingDB Entry DOI: 10.7270/Q2G44R39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase delta catalytic subunit (Homo sapiens (Human)) | BDBM50090910 (3alpha,16,17,18-tetrahydroxyaphidicolone | 6,13-di...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Pharmacia Corporation Curated by ChEMBL | Assay Description Inhibition of human delta DNA polymerase (95 uL) activity in a solution containg 6.4 mM HEPES (pH 7.5) upon incubation for 12 minutes at 26 degrees C... | J Med Chem 48: 5794-804 (2005) Article DOI: 10.1021/jm050162b BindingDB Entry DOI: 10.7270/Q2G44R39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase delta catalytic subunit (Homo sapiens (Human)) | BDBM50172517 (4-Hydroxy-6-(3-hydroxy-propyl)-quinoline-3-carboxy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Pharmacia Corporation Curated by ChEMBL | Assay Description Inhibition of human delta DNA polymerase (95 uL) activity in a solution containg 6.4 mM HEPES (pH 7.5) upon incubation for 12 minutes at 26 degrees C... | J Med Chem 48: 5794-804 (2005) Article DOI: 10.1021/jm050162b BindingDB Entry DOI: 10.7270/Q2G44R39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase delta catalytic subunit (Homo sapiens (Human)) | BDBM50172514 (7-Methyl-2-morpholin-4-ylmethyl-4-oxo-4,7-dihydro-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Pharmacia Corporation Curated by ChEMBL | Assay Description Inhibition of human delta DNA polymerase (95 uL) activity in a solution containg 6.4 mM HEPES (pH 7.5) upon incubation for 12 minutes at 26 degrees C... | J Med Chem 48: 5794-804 (2005) Article DOI: 10.1021/jm050162b BindingDB Entry DOI: 10.7270/Q2G44R39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase delta catalytic subunit (Homo sapiens (Human)) | BDBM50379292 (CHEMBL2011646) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.45E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Science University of Tokyo Curated by ChEMBL | Assay Description Inhibition of human DNA polymerase delta assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 after 60 mins | J Nat Prod 75: 135-41 (2012) Article DOI: 10.1021/np200523b BindingDB Entry DOI: 10.7270/Q2T154NG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase delta catalytic subunit (Homo sapiens (Human)) | BDBM50379293 (CHEMBL2011648) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Science University of Tokyo Curated by ChEMBL | Assay Description Inhibition of human DNA polymerase delta assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 after 60 mins | J Nat Prod 75: 135-41 (2012) Article DOI: 10.1021/np200523b BindingDB Entry DOI: 10.7270/Q2T154NG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase delta catalytic subunit (Homo sapiens (Human)) | BDBM50379294 (CHEMBL2011647) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.64E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Science University of Tokyo Curated by ChEMBL | Assay Description Inhibition of human DNA polymerase delta assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 after 60 mins | J Nat Prod 75: 135-41 (2012) Article DOI: 10.1021/np200523b BindingDB Entry DOI: 10.7270/Q2T154NG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase delta catalytic subunit (Homo sapiens (Human)) | BDBM50428818 (CHEMBL3142662) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kobe Gakuin University Curated by ChEMBL | Assay Description Inhibition of human DNA polymerase delta using poly(dA)/oligo(dT)18 (A/T, 2/1)/dTTP DNA template-primer substrate measured at 37 degC for 60 mins | Bioorg Med Chem 21: 403-11 (2012) Article DOI: 10.1016/j.bmc.2012.11.024 BindingDB Entry DOI: 10.7270/Q2833TC4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase delta catalytic subunit (Homo sapiens (Human)) | BDBM50208251 (3-5-dimethyl-8-methoxy-3,4-dihydroisocoumarin | CH...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Science University of Tokyo Curated by ChEMBL | Assay Description Inhibition of human DNA polymerase delta | Bioorg Med Chem 15: 3109-14 (2007) Article DOI: 10.1016/j.bmc.2007.02.052 BindingDB Entry DOI: 10.7270/Q2GQ6ZKP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase delta catalytic subunit (Homo sapiens (Human)) | BDBM50208250 (3-methyl-8-methoxy-3,4-dihydroisocoumarin | CHEMBL...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Science University of Tokyo Curated by ChEMBL | Assay Description Inhibition of human DNA polymerase delta | Bioorg Med Chem 15: 3109-14 (2007) Article DOI: 10.1016/j.bmc.2007.02.052 BindingDB Entry DOI: 10.7270/Q2GQ6ZKP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase delta catalytic subunit (Homo sapiens (Human)) | BDBM50208246 (5-formyl-8-hydroxy-3-methyl-3,4-dihydroisocoumarin...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Science University of Tokyo Curated by ChEMBL | Assay Description Inhibition of human DNA polymerase delta | Bioorg Med Chem 15: 3109-14 (2007) Article DOI: 10.1016/j.bmc.2007.02.052 BindingDB Entry DOI: 10.7270/Q2GQ6ZKP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase delta catalytic subunit (Homo sapiens (Human)) | BDBM50208249 (3-methyl-8-hydroxy-3,4-dihydroisocoumarin | CHEMBL...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Science University of Tokyo Curated by ChEMBL | Assay Description Inhibition of human DNA polymerase delta | Bioorg Med Chem 15: 3109-14 (2007) Article DOI: 10.1016/j.bmc.2007.02.052 BindingDB Entry DOI: 10.7270/Q2GQ6ZKP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase delta catalytic subunit (Homo sapiens (Human)) | BDBM50208248 ((1,2,3,4-tetrahydro-5-methoxynaphthalene-1,4-diol ...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Science University of Tokyo Curated by ChEMBL | Assay Description Inhibition of human DNA polymerase delta | Bioorg Med Chem 15: 3109-14 (2007) Article DOI: 10.1016/j.bmc.2007.02.052 BindingDB Entry DOI: 10.7270/Q2GQ6ZKP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase delta catalytic subunit (Homo sapiens (Human)) | BDBM50208247 ((3,4-dihydro-4-hydroxy-8-methoxynaphthalene-1(2H)-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Science University of Tokyo Curated by ChEMBL | Assay Description Inhibition of human DNA polymerase delta | Bioorg Med Chem 15: 3109-14 (2007) Article DOI: 10.1016/j.bmc.2007.02.052 BindingDB Entry DOI: 10.7270/Q2GQ6ZKP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase delta catalytic subunit (Homo sapiens (Human)) | BDBM50208245 (5-hydroxy-3-hydroxymethyl-2-methyl-7-methoxychromo...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Science University of Tokyo Curated by ChEMBL | Assay Description Inhibition of human DNA polymerase delta | Bioorg Med Chem 15: 3109-14 (2007) Article DOI: 10.1016/j.bmc.2007.02.052 BindingDB Entry DOI: 10.7270/Q2GQ6ZKP | |||||||||||
More data for this Ligand-Target Pair |