Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Elongation of very long chain fatty acids protein 3 (Homo sapiens (Human)) | BDBM50250164 (6,6-dimethyl-3-(5-methyl-3-oxo-2-phenyl-2,3-dihydr...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >10 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute Curated by ChEMBL | Assay Description Inhibition of human ELOVL3 expressed in african green monkey COS7 cells assessed as stearoyl-CoA elongation | J Med Chem 52: 3142-5 (2009) Article DOI: 10.1021/jm900391x BindingDB Entry DOI: 10.7270/Q20P0ZX6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Elongation of very long chain fatty acids protein 3 (Homo sapiens (Human)) | BDBM50249844 (3-[2-(4-isopropylphenyl)-5-methyl-3-oxo-2,3-dihydr...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 59 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute Curated by ChEMBL | Assay Description Inhibition of human ELOVL3 expressed in african green monkey COS7 cells assessed as stearoyl-CoA elongation | J Med Chem 52: 3142-5 (2009) Article DOI: 10.1021/jm900391x BindingDB Entry DOI: 10.7270/Q20P0ZX6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Elongation of very long chain fatty acids protein 3 (Homo sapiens (Human)) | BDBM50299971 (4-Fluoro-N-{[(+)-(4S)-2-oxo-6-(1H-pyrazol-5-yl)-4-...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute Curated by ChEMBL | Assay Description Inhibition of human ELOVL3 | J Med Chem 52: 7289-300 (2009) Article DOI: 10.1021/jm900915x BindingDB Entry DOI: 10.7270/Q2XK8FMB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Elongation of very long chain fatty acids protein 3 (Homo sapiens (Human)) | BDBM50249791 (3-[2-(4-chlorophenyl)-5-methyl-3-oxo-2,3-dihydro-1...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 221 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute Curated by ChEMBL | Assay Description Inhibition of human ELOVL3 expressed in african green monkey COS7 cells assessed as stearoyl-CoA elongation | J Med Chem 52: 3142-5 (2009) Article DOI: 10.1021/jm900391x BindingDB Entry DOI: 10.7270/Q20P0ZX6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Elongation of very long chain fatty acids protein 3 (Homo sapiens (Human)) | BDBM50249892 (6,6-dimethyl-3-{5-methyl-3-oxo-2-[4-(trifluorometh...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 337 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute Curated by ChEMBL | Assay Description Inhibition of human ELOVL3 expressed in african green monkey COS7 cells assessed as stearoyl-CoA elongation | J Med Chem 52: 3142-5 (2009) Article DOI: 10.1021/jm900391x BindingDB Entry DOI: 10.7270/Q20P0ZX6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Elongation of very long chain fatty acids protein 3 (Homo sapiens (Human)) | BDBM50249891 (3-[2-(4-methyllphenyl)-5-methyl-3-oxo-2,3-dihydro-...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 375 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute Curated by ChEMBL | Assay Description Inhibition of human ELOVL3 expressed in african green monkey COS7 cells assessed as stearoyl-CoA elongation | J Med Chem 52: 3142-5 (2009) Article DOI: 10.1021/jm900391x BindingDB Entry DOI: 10.7270/Q20P0ZX6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Elongation of very long chain fatty acids protein 3 (Homo sapiens (Human)) | BDBM50249815 (3-[2-(4-methoxyphenyl)-5-methyl-3-oxo-2,3-dihydro-...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 503 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute Curated by ChEMBL | Assay Description Inhibition of human ELOVL3 expressed in african green monkey COS7 cells assessed as stearoyl-CoA elongation | J Med Chem 52: 3142-5 (2009) Article DOI: 10.1021/jm900391x BindingDB Entry DOI: 10.7270/Q20P0ZX6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Elongation of very long chain fatty acids protein 3 (Homo sapiens (Human)) | BDBM50249843 (3-[2-(4-cyanophenyl)-5-methyl-3-oxo-2,3-dihydro-1H...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute Curated by ChEMBL | Assay Description Inhibition of human ELOVL3 expressed in african green monkey COS7 cells assessed as stearoyl-CoA elongation | J Med Chem 52: 3142-5 (2009) Article DOI: 10.1021/jm900391x BindingDB Entry DOI: 10.7270/Q20P0ZX6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Elongation of very long chain fatty acids protein 3 (Homo sapiens (Human)) | BDBM50298968 ((1R*,4S*,6R*)-(+/-)-2-[(1-Methyl-1H-imidazol-4-yl)...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute Curated by ChEMBL | Assay Description Inhibition of C-terminal V5-epitope-tagged human ELOVL3 expressed in african green monkey COS7 cells | Bioorg Med Chem 17: 5639-47 (2009) Article DOI: 10.1016/j.bmc.2009.06.042 BindingDB Entry DOI: 10.7270/Q2WW7HQX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Elongation of very long chain fatty acids protein 3 (Homo sapiens (Human)) | BDBM50293789 (3-endo-(Pyridin-2-ylsulfonyl)-N-[4-(trifluoromethy...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.94E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute Curated by ChEMBL | Assay Description Inhibition of human ELOVL3 expressed in Pichia pastoris SND1168 | J Med Chem 52: 4111-4 (2009) Article DOI: 10.1021/jm900488k BindingDB Entry DOI: 10.7270/Q25D8SRQ | |||||||||||
More data for this Ligand-Target Pair |