Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Excitatory amino acid transporter 1 (Rattus norvegicus) | BDBM50292997 (2-Amino-4-(4-methoxyphenyl)-7-(naphthalene-1-yl)-5...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 970 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Activity at rat EAAT1 expressed in TSA201 cells assessed as inhibition of Glu-induced fluorescent response by FLIPR membrane potential blue assay | J Med Chem 52: 912-5 (2009) Article DOI: 10.1021/jm8013458 BindingDB Entry DOI: 10.7270/Q2PV6KCP | |||||||||||
More data for this Ligand-Target Pair |