BindingDB PrimarySearch

Found 27 hits Enz. Inhib. hit(s) with Target = 'Fatty acid synthase' AND taxid = 9031
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Fatty acid synthase (Gallus gallus (Chicken))	BDBM50362887 (AVICULARIN) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.15E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University Curated by ChEMBL					Assay Description Inhibition of chicken liver FASN				J Med Chem 54: 5615-38 (2011) Article DOI: 10.1021/jm2005805 BindingDB Entry DOI: 10.7270/Q21N8261
Wayne State University Curated by ChEMBL					More data for this Ligand-Target Pair
Fatty acid synthase (Gallus gallus (Chicken))	BDBM50318454 (CHEMBL123040 \| Diallyl trisulfide \| diallyltrisulf...) Show SMILES C=CCSSSCC=C Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	8.37E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University Curated by ChEMBL					Assay Description Inhibition of chicken liver FASN				J Med Chem 54: 5615-38 (2011) Article DOI: 10.1021/jm2005805 BindingDB Entry DOI: 10.7270/Q21N8261
Wayne State University Curated by ChEMBL					More data for this Ligand-Target Pair
Fatty acid synthase (Gallus gallus (Chicken))	BDBM50318454 (CHEMBL123040 \| Diallyl trisulfide \| diallyltrisulf...) Show SMILES C=CCSSSCC=C Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	8.37E+3	n/a	n/a	n/a	n/a	7.0	37
Graduate University of Chinese Academy of Sciences					Assay Description FAS activity was determined by monitoring the decrease in absorbence at 340 nm resulting from the oxidation of NADPH using an Amersham Pharmacia Ultr...				J Enzyme Inhib Med Chem 25: 290-5 (2010) Article DOI: 10.3109/14756360903179377 BindingDB Entry DOI: 10.7270/Q2KS6QFM
Graduate University of Chinese Academy of Sciences					More data for this Ligand-Target Pair
Fatty acid synthase (Gallus gallus (Chicken))	BDBM240798 (Ginkgolic acid C17:2 (2)) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.20E+3	n/a	n/a	n/a	n/a	7.0	37
Yeungnam University					Assay Description To each microtube (final volume: 100 μL), FAS was added (20-30 μg protein) in a buffer containing 100 mM potassium phosphate (pH 7.0), 2.5 ...				J Enzyme Inhib Med Chem 28: 565-8 (2013) Article DOI: 10.3109/14756366.2012.658786 BindingDB Entry DOI: 10.7270/Q2D21WHW
Yeungnam University					More data for this Ligand-Target Pair
Fatty acid synthase (Gallus gallus (Chicken))	BDBM50259930 (6-(10'Z-heptadecenyl)-salicylicacid \| 6-[10'(Z)-he...) Show SMILES CCCCCC\C=C/CCCCCCCCCc1cccc(O)c1C(O)=O Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.05E+4	n/a	n/a	n/a	n/a	7.0	37
Yeungnam University					Assay Description To each microtube (final volume: 100 μL), FAS was added (20-30 μg protein) in a buffer containing 100 mM potassium phosphate (pH 7.0), 2.5 ...				J Enzyme Inhib Med Chem 28: 565-8 (2013) Article DOI: 10.3109/14756366.2012.658786 BindingDB Entry DOI: 10.7270/Q2D21WHW
Yeungnam University					More data for this Ligand-Target Pair
Fatty acid synthase (Gallus gallus (Chicken))	BDBM50349517 (CHEMBL1808693) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.27E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of chicken FAS by spectrophotometric analysis				Bioorg Med Chem Lett 21: 4742-4 (2011) Article DOI: 10.1016/j.bmcl.2011.06.075 BindingDB Entry DOI: 10.7270/Q2RV0P27
Sichuan University Curated by ChEMBL					More data for this Ligand-Target Pair
Fatty acid synthase (Gallus gallus (Chicken))	BDBM50009248 ((2R,3S)-3-((4E,7E)-Nona-4,7-dienoyl)-oxirane-2-car...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	7.0	37
Yeungnam University					Assay Description To each microtube (final volume: 100 μL), FAS was added (20-30 μg protein) in a buffer containing 100 mM potassium phosphate (pH 7.0), 2.5 ...				J Enzyme Inhib Med Chem 28: 565-8 (2013) Article DOI: 10.3109/14756366.2012.658786 BindingDB Entry DOI: 10.7270/Q2D21WHW
Yeungnam University					More data for this Ligand-Target Pair
Fatty acid synthase (Gallus gallus (Chicken))	BDBM50148911 ((3beta)-3-hydroxyurs-12-en-28-oic acid \| 3beta-hyd...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.31E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University Curated by ChEMBL					Assay Description Inhibition of chicken liver FASN				J Med Chem 54: 5615-38 (2011) Article DOI: 10.1021/jm2005805 BindingDB Entry DOI: 10.7270/Q21N8261
Wayne State University Curated by ChEMBL					More data for this Ligand-Target Pair
Fatty acid synthase (Gallus gallus (Chicken))	CHEMBL5269517 Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL UniChem		n/a	n/a	1.56E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Fatty acid synthase (Gallus gallus (Chicken))	CHEMBL5271377 Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL UniChem		n/a	n/a	1.56E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Fatty acid synthase (Gallus gallus (Chicken))	CHEMBL5274276 Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL UniChem		n/a	n/a	1.56E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Fatty acid synthase (Gallus gallus (Chicken))	CHEMBL5266900 Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL UniChem		n/a	n/a	1.56E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Fatty acid synthase (Gallus gallus (Chicken))	CHEMBL5283434 Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL UniChem		n/a	n/a	1.56E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Fatty acid synthase (Gallus gallus (Chicken))	BDBM50394659 (CHEMBL2165410) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University Curated by ChEMBL					Assay Description Inhibition of chicken liver FASN ketoreductase activity				J Med Chem 54: 5615-38 (2011) Article DOI: 10.1021/jm2005805 BindingDB Entry DOI: 10.7270/Q21N8261
Wayne State University Curated by ChEMBL					More data for this Ligand-Target Pair
Fatty acid synthase (Gallus gallus (Chicken))	BDBM50242188 (6-(8'Z-pentadecenyl)-salicylicacid \| 6-[8'(Z)-pent...) Show SMILES CCCCCC\C=C/CCCCCCCc1cccc(O)c1C(O)=O Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.71E+4	n/a	n/a	n/a	n/a	7.0	37
Yeungnam University					Assay Description To each microtube (final volume: 100 μL), FAS was added (20-30 μg protein) in a buffer containing 100 mM potassium phosphate (pH 7.0), 2.5 ...				J Enzyme Inhib Med Chem 28: 565-8 (2013) Article DOI: 10.3109/14756366.2012.658786 BindingDB Entry DOI: 10.7270/Q2D21WHW
Yeungnam University					More data for this Ligand-Target Pair
Fatty acid synthase (Gallus gallus (Chicken))	BDBM50394660 (CHEMBL2165409) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University Curated by ChEMBL					Assay Description Inhibition of chicken liver FASN ketoreductase activity				J Med Chem 54: 5615-38 (2011) Article DOI: 10.1021/jm2005805 BindingDB Entry DOI: 10.7270/Q21N8261
Wayne State University Curated by ChEMBL					More data for this Ligand-Target Pair
Fatty acid synthase (Gallus gallus (Chicken))	BDBM50153015 ((-)-Epicatechin-3-gallate \| (-)-epicatechin 3-O-ga...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University Curated by ChEMBL					Assay Description Inhibition of chicken liver FASN after 3 hrs				J Med Chem 54: 5615-38 (2011) Article DOI: 10.1021/jm2005805 BindingDB Entry DOI: 10.7270/Q21N8261
Wayne State University Curated by ChEMBL					More data for this Ligand-Target Pair
Fatty acid synthase (Gallus gallus (Chicken))	BDBM50070942 ((-)-Epigallocatechin gallate \| (-)-Epigallocatechi...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University Curated by ChEMBL					Assay Description Inhibition of chicken liver FASN				J Med Chem 54: 5615-38 (2011) Article DOI: 10.1021/jm2005805 BindingDB Entry DOI: 10.7270/Q21N8261
Wayne State University Curated by ChEMBL					More data for this Ligand-Target Pair
Fatty acid synthase (Gallus gallus (Chicken))	BDBM50070942 ((-)-Epigallocatechin gallate \| (-)-Epigallocatechi...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
National University of Singapore Curated by ChEMBL					Assay Description Inhibition of chicken liver FASN using acetyl-CoA, malonyl-CoA and NADPH as substrate by spectrophotometer analysis				Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111597 BindingDB Entry DOI: 10.7270/Q2R78JN1
National University of Singapore Curated by ChEMBL					More data for this Ligand-Target Pair
Fatty acid synthase (Gallus gallus (Chicken))	BDBM50148911 ((3beta)-3-hydroxyurs-12-en-28-oic acid \| 3beta-hyd...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	5.93E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University Curated by ChEMBL					Assay Description Inhibition of chicken liver FASN ketoreductase activity				J Med Chem 54: 5615-38 (2011) Article DOI: 10.1021/jm2005805 BindingDB Entry DOI: 10.7270/Q21N8261
Wayne State University Curated by ChEMBL					More data for this Ligand-Target Pair
Fatty acid synthase (Gallus gallus (Chicken))	BDBM7459 (2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4...) Show SMILES Oc1cc(O)c2c(c1)oc(cc2=O)-c1ccc(O)c(O)c1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	6.25E+4	n/a	n/a	n/a	n/a	7.0	37
Yeungnam University					Assay Description To each microtube (final volume: 100 μL), FAS was added (20-30 μg protein) in a buffer containing 100 mM potassium phosphate (pH 7.0), 2.5 ...				J Enzyme Inhib Med Chem 28: 565-8 (2013) Article DOI: 10.3109/14756366.2012.658786 BindingDB Entry DOI: 10.7270/Q2D21WHW
Yeungnam University					More data for this Ligand-Target Pair
Fatty acid synthase (Gallus gallus (Chicken))	BDBM50153015 ((-)-Epicatechin-3-gallate \| (-)-epicatechin 3-O-ga...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University Curated by ChEMBL					Assay Description Inhibition of chicken liver FASN ketoreductase activity				J Med Chem 54: 5615-38 (2011) Article DOI: 10.1021/jm2005805 BindingDB Entry DOI: 10.7270/Q21N8261
Wayne State University Curated by ChEMBL					More data for this Ligand-Target Pair
Fatty acid synthase (Gallus gallus (Chicken))	BDBM50256128 ((2R,3S)-4-methylene-2-octyl-5-oxotetrahydrofuran-3...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University Curated by ChEMBL					Assay Description Inhibition of chicken liver FASN ketoreductase activity				J Med Chem 54: 5615-38 (2011) Article DOI: 10.1021/jm2005805 BindingDB Entry DOI: 10.7270/Q21N8261
Wayne State University Curated by ChEMBL					More data for this Ligand-Target Pair
Fatty acid synthase (Gallus gallus (Chicken))	BDBM50394663 (CHEMBL2165267) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University Curated by ChEMBL					Assay Description Inhibition of chicken liver FASN ketoreductase activity				J Med Chem 54: 5615-38 (2011) Article DOI: 10.1021/jm2005805 BindingDB Entry DOI: 10.7270/Q21N8261
Wayne State University Curated by ChEMBL					More data for this Ligand-Target Pair
Fatty acid synthase (Gallus gallus (Chicken))	BDBM50070942 ((-)-Epigallocatechin gallate \| (-)-Epigallocatechi...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University Curated by ChEMBL					Assay Description Inhibition of chicken liver FASN ketoreductase activity				J Med Chem 54: 5615-38 (2011) Article DOI: 10.1021/jm2005805 BindingDB Entry DOI: 10.7270/Q21N8261
Wayne State University Curated by ChEMBL					More data for this Ligand-Target Pair
Fatty acid synthase (Gallus gallus (Chicken))	BDBM50318453 (3-Allyldisulfanyl-propene \| CHEMBL366603 \| Diallyl...) Show SMILES C=CCSSCC=C Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.45E+5	n/a	n/a	n/a	n/a	7.0	37
Graduate University of Chinese Academy of Sciences					Assay Description FAS activity was determined by monitoring the decrease in absorbence at 340 nm resulting from the oxidation of NADPH using an Amersham Pharmacia Ultr...				J Enzyme Inhib Med Chem 25: 290-5 (2010) Article DOI: 10.3109/14756360903179377 BindingDB Entry DOI: 10.7270/Q2KS6QFM
Graduate University of Chinese Academy of Sciences					More data for this Ligand-Target Pair
Fatty acid synthase (Gallus gallus (Chicken))	BDBM233038 (Dimethyl disulfide) Show SMILES CSSC Show InChI InChI=1S/C2H6S2/c1-3-4-2/h1-2H3	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.21E+6	n/a	n/a	n/a	n/a	7.0	37
Graduate University of Chinese Academy of Sciences					Assay Description FAS activity was determined by monitoring the decrease in absorbence at 340 nm resulting from the oxidation of NADPH using an Amersham Pharmacia Ultr...				J Enzyme Inhib Med Chem 25: 290-5 (2010) Article DOI: 10.3109/14756360903179377 BindingDB Entry DOI: 10.7270/Q2KS6QFM
Graduate University of Chinese Academy of Sciences					More data for this Ligand-Target Pair