Compile Data Set for Download or QSAR

Found 7 hits Enz. Inhib. hit(s) with Target = '4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT5' AND taxid = 9606   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT5 (Homo sapiens (Human))	BDBM50366926 (CHEMBL609638) Show SMILES CC1CC(OP(O)(=O)OP(O)(=O)OC[C@H]2OC([C@H](O)[C@@H]2O)n2cnc3c2nc(N)[nH]c3=O)C(O)C(O)C1O |r| Show InChI InChI=1S/C17H27N5O14P2/c1-5-2-6(10(24)12(26)9(5)23)35-38(31,32)36-37(29,30)33-3-7-11(25)13(27)16(34-7)22-4-19-8-14(22)20-17(18)21-15(8)28/h4-7,9-13,16,23-27H,2-3H2,1H3,(H,29,30)(H,31,32)(H3,18,20,21,28)/t5?,6?,7-,9?,10?,11-,12?,13-,16?/m1/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6.71E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
David Geffen School of Medicine at University of California Curated by ChEMBL					Assay Description Inhibition of Fucosyltransferase 5 by the compound was evaluated; Competitive inhibition				Bioorg Med Chem Lett 14: 571-3 (2004) BindingDB Entry DOI: 10.7270/Q2MS3TBP
					More data for this Ligand-Target Pair
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT5 (Homo sapiens (Human))	BDBM50366925 (CHEMBL610712) Show SMILES CC1OC(CP(O)(=O)OP(O)(=O)OC[C@H]2OC([C@H](O)[C@@H]2O)n2cnc3c2nc(N)[nH]c3=O)C(O)C(O)C1O |r| Show InChI InChI=1S/C17H27N5O14P2/c1-5-9(23)12(26)11(25)7(34-5)3-37(29,30)36-38(31,32)33-2-6-10(24)13(27)16(35-6)22-4-19-8-14(22)20-17(18)21-15(8)28/h4-7,9-13,16,23-27H,2-3H2,1H3,(H,29,30)(H,31,32)(H3,18,20,21,28)/t5?,6-,7?,9?,10-,11?,12?,13-,16?/m1/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8.89E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
David Geffen School of Medicine at University of California Curated by ChEMBL					Assay Description Inhibition of Fucosyltransferase 5 by the compound was evaluated; Weak competitive inhibition				Bioorg Med Chem Lett 14: 571-3 (2004) BindingDB Entry DOI: 10.7270/Q2MS3TBP
					More data for this Ligand-Target Pair
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT5 (Homo sapiens (Human))	BDBM50101904 (CHEMBL52741 | GDP-Azasugar analogue) Show SMILES C[C@@H]1[NH2+][C@H](COP([O-])(=O)OP([O-])(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2cnc3c2nc([NH3+])[nH]c3=O)[C@@H](O)[C@@H]1O Show InChI InChI=1S/C16H26N6O13P2/c1-5-9(23)10(24)6(19-5)2-32-36(28,29)35-37(30,31)33-3-7-11(25)12(26)15(34-7)22-4-18-8-13(22)20-16(17)21-14(8)27/h4-7,9-12,15,19,23-26H,2-3H2,1H3,(H,28,29)(H,30,31)(H3,17,20,21,27)/t5-,6+,7+,9+,10+,11+,12+,15+/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universit£t Berlin Curated by ChEMBL					Assay Description Inhibition of GnRH-stimulated luteinizing hormone (LH) release in rat pituitary cells				Bioorg Med Chem Lett 11: 1809-11 (2001) BindingDB Entry DOI: 10.7270/Q2FF3SWF
					More data for this Ligand-Target Pair
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT5 (Homo sapiens (Human))	BDBM92459 (CHEMBL384759 | GDP | Guanosine Diphosphate) Show SMILES Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O Show InChI InChI=1S/C10H15N5O11P2/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(25-9)1-24-28(22,23)26-27(19,20)21/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H2,19,20,21)(H3,11,13,14,18)/t3-,5-,6-,9-/m1/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	PubMed	n/a	n/a	6.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universit£t Berlin Curated by ChEMBL					Assay Description Inhibitory activity against fucosyltransferase (FucT V) in the presence of fucosyl acceptor N-acetyllactosamine				Bioorg Med Chem Lett 11: 1809-11 (2001) BindingDB Entry DOI: 10.7270/Q2FF3SWF
					More data for this Ligand-Target Pair
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT5 (Homo sapiens (Human))	BDBM50101904 (CHEMBL52741 | GDP-Azasugar analogue) Show SMILES C[C@@H]1[NH2+][C@H](COP([O-])(=O)OP([O-])(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2cnc3c2nc([NH3+])[nH]c3=O)[C@@H](O)[C@@H]1O Show InChI InChI=1S/C16H26N6O13P2/c1-5-9(23)10(24)6(19-5)2-32-36(28,29)35-37(30,31)33-3-7-11(25)12(26)15(34-7)22-4-18-8-13(22)20-16(17)21-14(8)27/h4-7,9-12,15,19,23-26H,2-3H2,1H3,(H,28,29)(H,30,31)(H3,17,20,21,27)/t5-,6+,7+,9+,10+,11+,12+,15+/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universit£t Berlin Curated by ChEMBL					Assay Description Inhibitory activity against fucosyltransferase (FucT V) in the presence of 10 mM fucosyl acceptor N-acetyllactosamine				Bioorg Med Chem Lett 11: 1809-11 (2001) BindingDB Entry DOI: 10.7270/Q2FF3SWF
					More data for this Ligand-Target Pair
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT5 (Homo sapiens (Human))	BDBM50101907 (({[(2R,3S,4R,5R)-5-(2-azaniumyl-6-hydroxy-9H-purin...) Show SMILES CP([O-])(=O)OP([O-])(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c1nc([NH3+])[nH]c2=O Show InChI InChI=1S/C11H17N5O10P2/c1-27(20,21)26-28(22,23)24-2-4-6(17)7(18)10(25-4)16-3-13-5-8(16)14-11(12)15-9(5)19/h3-4,6-7,10,17-18H,2H2,1H3,(H,20,21)(H,22,23)(H3,12,14,15,19)/p-1/t4-,6-,7-,10-/m1/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universit£t Berlin Curated by ChEMBL					Assay Description Inhibitory activity against fucosyltransferase (FucT V) in the presence of fucosyl acceptor N-acetyllactosamine				Bioorg Med Chem Lett 11: 1809-11 (2001) BindingDB Entry DOI: 10.7270/Q2FF3SWF
					More data for this Ligand-Target Pair
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT5 (Homo sapiens (Human))	BDBM50101906 (CHEMBL53188 | GDP-Azasugar analogue) Show SMILES [NH3+]CCOP([O-])(=O)OP([O-])(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c1nc([NH3+])[nH]c2=O Show InChI InChI=1S/C12H20N6O11P2/c13-1-2-26-30(22,23)29-31(24,25)27-3-5-7(19)8(20)11(28-5)18-4-15-6-9(18)16-12(14)17-10(6)21/h4-5,7-8,11,19-20H,1-3,13H2,(H,22,23)(H,24,25)(H3,14,16,17,21)/t5-,7-,8-,11-/m1/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universit£t Berlin Curated by ChEMBL					Assay Description Inhibitory activity against fucosyltransferase (FucT V) in the presence of fucosyl acceptor N-acetyllactosamine				Bioorg Med Chem Lett 11: 1809-11 (2001) BindingDB Entry DOI: 10.7270/Q2FF3SWF
					More data for this Ligand-Target Pair