Compile Data Set for Download or QSAR

Found 9 hits Enz. Inhib. hit(s) with Target = 'N-methyl-D-aspartate receptor' AND taxid = 9823   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
N-methyl-D-aspartate receptor (Sus scrofa)	BDBM50089759 ((R)-1-(4-Chloro-phenyl)-2-[4-(4-fluoro-benzyl)-pip...) Show SMILES O[C@@H](CN1CCC(Cc2ccc(F)cc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C20H23ClFNO/c21-18-5-3-17(4-6-18)20(24)14-23-11-9-16(10-12-23)13-15-1-7-19(22)8-2-15/h1-8,16,20,24H,9-14H2/t20-/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Zentrum für Pharmaforschung Curated by ChEMBL					Assay Description Compound was tested for inhibition of [3H]-MK-801 binding to N-methyl-D-aspartate glutamate receptor at NR2B subunit in high affinity fraction of por...				Bioorg Med Chem Lett 10: 1377-80 (2000) BindingDB Entry DOI: 10.7270/Q2Q52NVP
					More data for this Ligand-Target Pair
N-methyl-D-aspartate receptor (Sus scrofa)	BDBM50079387 (1-(4-Chloro-phenyl)-2-[4-(4-fluoro-benzyl)-piperid...) Show SMILES OC(CN1CCC(Cc2ccc(F)cc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C20H23ClFNO/c21-18-5-3-17(4-6-18)20(24)14-23-11-9-16(10-12-23)13-15-1-7-19(22)8-2-15/h1-8,16,20,24H,9-14H2	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	83	n/a	n/a	n/a	n/a	n/a	n/a
Zentrum für Pharmaforschung Curated by ChEMBL					Assay Description Compound was tested for inhibition of [3H]-MK-801 binding to N-methyl-D-aspartate glutamate receptor at NR2B subunit in high affinity fraction of por...				Bioorg Med Chem Lett 10: 1377-80 (2000) BindingDB Entry DOI: 10.7270/Q2Q52NVP
					More data for this Ligand-Target Pair
N-methyl-D-aspartate receptor (Sus scrofa)	BDBM50089759 ((R)-1-(4-Chloro-phenyl)-2-[4-(4-fluoro-benzyl)-pip...) Show SMILES O[C@@H](CN1CCC(Cc2ccc(F)cc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C20H23ClFNO/c21-18-5-3-17(4-6-18)20(24)14-23-11-9-16(10-12-23)13-15-1-7-19(22)8-2-15/h1-8,16,20,24H,9-14H2/t20-/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	213	n/a	n/a	n/a	n/a	n/a	n/a
Zentrum für Pharmaforschung Curated by ChEMBL					Assay Description Displacement of [3H]-ifendropil from binding site of N-methyl-D-aspartate glutamate receptor was evaluated employing synaptosomal fraction of porcine...				Bioorg Med Chem Lett 10: 1377-80 (2000) BindingDB Entry DOI: 10.7270/Q2Q52NVP
					More data for this Ligand-Target Pair
N-methyl-D-aspartate receptor (Sus scrofa)	BDBM50079387 (1-(4-Chloro-phenyl)-2-[4-(4-fluoro-benzyl)-piperid...) Show SMILES OC(CN1CCC(Cc2ccc(F)cc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C20H23ClFNO/c21-18-5-3-17(4-6-18)20(24)14-23-11-9-16(10-12-23)13-15-1-7-19(22)8-2-15/h1-8,16,20,24H,9-14H2	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	277	n/a	n/a	n/a	n/a	n/a	n/a
Zentrum für Pharmaforschung Curated by ChEMBL					Assay Description Displacement of [3H]-ifendropil from binding site of N-methyl-D-aspartate glutamate receptor was evaluated employing synaptosomal fraction of porcine...				Bioorg Med Chem Lett 10: 1377-80 (2000) BindingDB Entry DOI: 10.7270/Q2Q52NVP
					More data for this Ligand-Target Pair
N-methyl-D-aspartate receptor (Sus scrofa)	BDBM50089760 ((S)-1-(4-Chloro-phenyl)-2-[4-(4-fluoro-benzyl)-pip...) Show SMILES O[C@H](CN1CCC(Cc2ccc(F)cc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C20H23ClFNO/c21-18-5-3-17(4-6-18)20(24)14-23-11-9-16(10-12-23)13-15-1-7-19(22)8-2-15/h1-8,16,20,24H,9-14H2/t20-/m1/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	545	n/a	n/a	n/a	n/a	n/a	n/a
Zentrum für Pharmaforschung Curated by ChEMBL					Assay Description Displacement of [3H]-ifendropil from binding site of N-methyl-D-aspartate glutamate receptor was evaluated employing synaptosomal fraction of porcine...				Bioorg Med Chem Lett 10: 1377-80 (2000) BindingDB Entry DOI: 10.7270/Q2Q52NVP
					More data for this Ligand-Target Pair
N-methyl-D-aspartate receptor (Sus scrofa)	BDBM50089760 ((S)-1-(4-Chloro-phenyl)-2-[4-(4-fluoro-benzyl)-pip...) Show SMILES O[C@H](CN1CCC(Cc2ccc(F)cc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C20H23ClFNO/c21-18-5-3-17(4-6-18)20(24)14-23-11-9-16(10-12-23)13-15-1-7-19(22)8-2-15/h1-8,16,20,24H,9-14H2/t20-/m1/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Zentrum für Pharmaforschung Curated by ChEMBL					Assay Description Compound was tested for inhibition of [3H]-MK-801 binding to N-methyl-D-aspartate glutamate receptor at NR2B subunit in high affinity fraction of por...				Bioorg Med Chem Lett 10: 1377-80 (2000) BindingDB Entry DOI: 10.7270/Q2Q52NVP
					More data for this Ligand-Target Pair
N-methyl-D-aspartate receptor (Sus scrofa)	BDBM50089760 ((S)-1-(4-Chloro-phenyl)-2-[4-(4-fluoro-benzyl)-pip...) Show SMILES O[C@H](CN1CCC(Cc2ccc(F)cc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C20H23ClFNO/c21-18-5-3-17(4-6-18)20(24)14-23-11-9-16(10-12-23)13-15-1-7-19(22)8-2-15/h1-8,16,20,24H,9-14H2/t20-/m1/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Zentrum für Pharmaforschung Curated by ChEMBL					Assay Description Compound was tested for inhibition of [3H]-MK-801 binding to N-methyl-D-aspartate glutamate receptor lacking NR2B subunit in low affinity fraction of...				Bioorg Med Chem Lett 10: 1377-80 (2000) BindingDB Entry DOI: 10.7270/Q2Q52NVP
					More data for this Ligand-Target Pair
N-methyl-D-aspartate receptor (Sus scrofa)	BDBM50079387 (1-(4-Chloro-phenyl)-2-[4-(4-fluoro-benzyl)-piperid...) Show SMILES OC(CN1CCC(Cc2ccc(F)cc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C20H23ClFNO/c21-18-5-3-17(4-6-18)20(24)14-23-11-9-16(10-12-23)13-15-1-7-19(22)8-2-15/h1-8,16,20,24H,9-14H2	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.13E+4	n/a	n/a	n/a	n/a	n/a	n/a
Zentrum für Pharmaforschung Curated by ChEMBL					Assay Description Compound was tested for inhibition of [3H]-MK-801 binding to N-methyl-D-aspartate glutamate receptor lacking NR2B subunit in low affinity fraction of...				Bioorg Med Chem Lett 10: 1377-80 (2000) BindingDB Entry DOI: 10.7270/Q2Q52NVP
					More data for this Ligand-Target Pair
N-methyl-D-aspartate receptor (Sus scrofa)	BDBM50089759 ((R)-1-(4-Chloro-phenyl)-2-[4-(4-fluoro-benzyl)-pip...) Show SMILES O[C@@H](CN1CCC(Cc2ccc(F)cc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C20H23ClFNO/c21-18-5-3-17(4-6-18)20(24)14-23-11-9-16(10-12-23)13-15-1-7-19(22)8-2-15/h1-8,16,20,24H,9-14H2/t20-/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.37E+4	n/a	n/a	n/a	n/a	n/a	n/a
Zentrum für Pharmaforschung Curated by ChEMBL					Assay Description Compound was tested for inhibition of [3H]-MK-801 binding to N-methyl-D-aspartate glutamate receptor lacking NR2B subunit in low affinity fraction of...				Bioorg Med Chem Lett 10: 1377-80 (2000) BindingDB Entry DOI: 10.7270/Q2Q52NVP
					More data for this Ligand-Target Pair