Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'POU domain, class 3, transcription factor 3' AND taxid = 9606   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
POU domain, class 3, transcription factor 3 (Homo sapiens (Human))	BDBM50149547 (4-[(4-Hydroxy-phenylcarbamoyl)-methoxy]-naphthalen...) Show SMILES Oc1ccc(NC(=O)COc2ccc(C(=O)Nc3cccc(F)c3)c3ccccc23)cc1 Show InChI InChI=1S/C25H19FN2O4/c26-16-4-3-5-18(14-16)28-25(31)22-12-13-23(21-7-2-1-6-20(21)22)32-15-24(30)27-17-8-10-19(29)11-9-17/h1-14,29H,15H2,(H,27,30)(H,28,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.24E+5	n/a	n/a	n/a	n/a	n/a	n/a
The State University of New York Curated by ChEMBL					Assay Description Antagonistic activity against BRN1/DNA interaction by electrophoretic mobility shift assay				Bioorg Med Chem Lett 14: 3875-9 (2004) Article DOI: 10.1016/j.bmcl.2004.05.068 BindingDB Entry DOI: 10.7270/Q2ZS2VZW
					More data for this Ligand-Target Pair
POU domain, class 3, transcription factor 3 (Homo sapiens (Human))	BDBM50149549 (4-[(3-Hydroxy-phenylcarbamoyl)-methoxy]-naphthalen...) Show SMILES Oc1cccc(NC(=O)COc2ccc(C(=O)Nc3cccc(F)c3)c3ccccc23)c1 Show InChI InChI=1S/C25H19FN2O4/c26-16-5-3-6-17(13-16)28-25(31)22-11-12-23(21-10-2-1-9-20(21)22)32-15-24(30)27-18-7-4-8-19(29)14-18/h1-14,29H,15H2,(H,27,30)(H,28,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.42E+5	n/a	n/a	n/a	n/a	n/a	n/a
The State University of New York Curated by ChEMBL					Assay Description Antagonistic activity against BRN1/DNA interaction by electrophoretic mobility shift assay				Bioorg Med Chem Lett 14: 3875-9 (2004) Article DOI: 10.1016/j.bmcl.2004.05.068 BindingDB Entry DOI: 10.7270/Q2ZS2VZW
					More data for this Ligand-Target Pair
POU domain, class 3, transcription factor 3 (Homo sapiens (Human))	BDBM50149565 (4-[(2,2,2-Trifluoro-ethylcarbamoyl)-methoxy]-napht...) Show SMILES Fc1cccc(NC(=O)c2ccc(OCC(=O)NCC(F)(F)F)c3ccccc23)c1 Show InChI InChI=1S/C21H16F4N2O3/c22-13-4-3-5-14(10-13)27-20(29)17-8-9-18(16-7-2-1-6-15(16)17)30-11-19(28)26-12-21(23,24)25/h1-10H,11-12H2,(H,26,28)(H,27,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.62E+5	n/a	n/a	n/a	n/a	n/a	n/a
The State University of New York Curated by ChEMBL					Assay Description Antagonistic activity against BRN1/DNA interaction by electrophoretic mobility shift assay				Bioorg Med Chem Lett 14: 3875-9 (2004) Article DOI: 10.1016/j.bmcl.2004.05.068 BindingDB Entry DOI: 10.7270/Q2ZS2VZW
					More data for this Ligand-Target Pair
POU domain, class 3, transcription factor 3 (Homo sapiens (Human))	BDBM50149552 (4-Cyclopropylcarbamoylmethoxy-naphthalene-1-carbox...) Show SMILES Fc1cccc(NC(=O)c2ccc(OCC(=O)NC3CC3)c3ccccc23)c1 Show InChI InChI=1S/C22H19FN2O3/c23-14-4-3-5-16(12-14)25-22(27)19-10-11-20(18-7-2-1-6-17(18)19)28-13-21(26)24-15-8-9-15/h1-7,10-12,15H,8-9,13H2,(H,24,26)(H,25,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.10E+5	n/a	n/a	n/a	n/a	n/a	n/a
The State University of New York Curated by ChEMBL					Assay Description Antagonistic activity against BRN1/DNA interaction by electrophoretic mobility shift assay				Bioorg Med Chem Lett 14: 3875-9 (2004) Article DOI: 10.1016/j.bmcl.2004.05.068 BindingDB Entry DOI: 10.7270/Q2ZS2VZW
					More data for this Ligand-Target Pair