Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Insulin receptor substrate 1 (RAT) | BDBM86694 (N'-(3-Chloro-4-morpholinophenyl)-N-hydroxyform...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Patents | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co., Ltd Curated by PDSP Ki Database | J Pharmacol Exp Ther 314: 77-85 (2005) Article DOI: 10.1124/jpet.105.083964 BindingDB Entry DOI: 10.7270/Q2MW2FQQ | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin receptor (Rattus norvegicus (rat)) | BDBM482158 (BDBM50242742 | TAE684) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Genomics Institute of the Novartis Research Foundation Curated by ChEMBL | Assay Description Inhibition of InsR phosphorylation in rat H4-2E cells | Proc Natl Acad Sci U S A 104: 270-5 (2007) Article DOI: 10.1073/pnas.0609412103 BindingDB Entry DOI: 10.7270/Q2BP02K2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin receptor (Rattus norvegicus (rat)) | BDBM2683 (2-[1-(3-dimethylaminopropyl)-indol-3-yl]-3-(indol-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | 7.4 | 23 |
Laboratoires Glaxo | Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] lab... | J Biol Chem 266: 15771-81 (1991) BindingDB Entry DOI: 10.7270/Q2FF3QJ4 | |||||||||||
More data for this Ligand-Target Pair |