Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Kynureninase (Rattus norvegicus) | BDBM50109155 (2-Amino-4-hydroxy-4-(3-hydroxy-phenyl)-butyric aci...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | PubMed | 130 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of St Andrews Curated by ChEMBL | Assay Description Tested for binding affinity of the compound against kynureninase enzyme from rat | Bioorg Med Chem Lett 12: 361-3 (2002) BindingDB Entry DOI: 10.7270/Q2P26XFS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kynureninase (Rattus norvegicus) | BDBM50069730 (2-Amino-3-(2-amino-benzenesulfonyl)-propionic acid...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 1.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Glaxo Wellcome Research and Development Curated by ChEMBL | Assay Description Compound was tested for the binding affinity against kynureninase in rat liver | Bioorg Med Chem Lett 8: 133-8 (1999) BindingDB Entry DOI: 10.7270/Q2639NXW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kynureninase (Rattus norvegicus) | BDBM50069732 (2-Amino-3-(2-amino-5-methyl-benzenesulfonyl)-propi...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Glaxo Wellcome Research and Development Curated by ChEMBL | Assay Description Compound was tested for the inhibition of mammalian kynureninase in rat liver | Bioorg Med Chem Lett 8: 133-8 (1999) BindingDB Entry DOI: 10.7270/Q2639NXW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kynureninase (Rattus norvegicus) | BDBM50069731 (2-Amino-3-(2-amino-3-fluoro-benzenesulfonyl)-propi...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Glaxo Wellcome Research and Development Curated by ChEMBL | Assay Description Compound was tested for the inhibition of mammalian kynureninase in rat liver | Bioorg Med Chem Lett 8: 133-8 (1999) BindingDB Entry DOI: 10.7270/Q2639NXW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kynureninase (Rattus norvegicus) | BDBM50069729 (2-Amino-3-(2-amino-3-methoxy-benzenesulfonyl)-prop...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 2.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Glaxo Wellcome Research and Development Curated by ChEMBL | Assay Description Compound was tested for the inhibition of mammalian kynureninase in rat liver | Bioorg Med Chem Lett 8: 133-8 (1999) BindingDB Entry DOI: 10.7270/Q2639NXW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kynureninase (Rattus norvegicus) | BDBM50069730 (2-Amino-3-(2-amino-benzenesulfonyl)-propionic acid...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 3.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Glaxo Wellcome Research and Development Curated by ChEMBL | Assay Description Compound was tested for the inhibition of mammalian kynureninase in rat liver | Bioorg Med Chem Lett 8: 133-8 (1999) BindingDB Entry DOI: 10.7270/Q2639NXW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kynureninase (Rattus norvegicus) | BDBM50083950 ((S)-(+)-2-Amino-4-(3-nitro-phenyl)-4-oxo-butyric a...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 6.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Tested for inhibitory activity against kynureninase from rat liver | Bioorg Med Chem Lett 5: 1451-1454 (1995) Article DOI: 10.1016/0960-894X(95)00255-R BindingDB Entry DOI: 10.7270/Q2PR7VZZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kynureninase (Rattus norvegicus) | BDBM50040567 (CHEMBL158499 | ortho-nitrobenzoyl)alanine) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia Curated by ChEMBL | Assay Description Ability to inhibit kynureninase was determined in a competitive inhibition assay. | J Med Chem 37: 647-55 (1994) BindingDB Entry DOI: 10.7270/Q2VD703H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kynureninase (Rattus norvegicus) | BDBM50061907 ((+/-)-2-Amino-4-(3-nitro-phenyl)-4-oxo-butyric aci...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia Curated by ChEMBL | Assay Description Ability to inhibit kynureninase was determined in a competitive inhibition assay. | J Med Chem 37: 647-55 (1994) BindingDB Entry DOI: 10.7270/Q2VD703H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kynureninase (Rattus norvegicus) | BDBM50284766 ((R)-2-Amino-4-(3-nitro-phenyl)-4-oxo-butyric acid ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Tested for inhibitory activity against kynureninase from rat liver | Bioorg Med Chem Lett 5: 1451-1454 (1995) Article DOI: 10.1016/0960-894X(95)00255-R BindingDB Entry DOI: 10.7270/Q2PR7VZZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kynureninase (Rattus norvegicus) | BDBM50040570 (CHEMBL160527 | NICOTINOYLALANINENAL | nicotinoylal...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 8.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia Curated by ChEMBL | Assay Description Ability to inhibit kynureninase was determined in a competitive inhibition assay. | J Med Chem 37: 647-55 (1994) BindingDB Entry DOI: 10.7270/Q2VD703H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kynureninase (Rattus norvegicus) | BDBM50040568 (CHEMBL157866 | para-nitrobenzoyl)alanine) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 9.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia Curated by ChEMBL | Assay Description Ability to inhibit kynureninase was determined in a competitive inhibition assay. | J Med Chem 37: 647-55 (1994) BindingDB Entry DOI: 10.7270/Q2VD703H | |||||||||||
More data for this Ligand-Target Pair |