BindingDB PrimarySearch

Found 13 hits Enz. Inhib. hit(s) with Target = 'Lactoperoxidase' AND taxid = 9606
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Lactoperoxidase (Homo sapiens (Human))	BDBM50507390 (CHEMBL4482878 \| US10981879, Example 3) Show SMILES Nc1cc(SCc2ccccc2F)c2nn[nH]c2n1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human LPO assessed as reduction in H2O2 catalyzed 3,5-iodo tyrosine formation from 3-iodotyrosine and potassium iodide preincubated for...				ACS Med Chem Lett 9: 1175-1180 (2018) Article DOI: 10.1021/acsmedchemlett.8b00308 BindingDB Entry DOI: 10.7270/Q2W0997Z
					More data for this Ligand-Target Pair
Lactoperoxidase (Homo sapiens (Human))	BDBM50275890 (CHEMBL457523 \| ethyl 2,3-dihydro-3-methyl-2-seleno...) Show SMILES CCOC(=O)n1ccn(C)[c]1=[Se] Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.01E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Science Curated by ChEMBL					Assay Description Inhibition of lactoperoxidase (unknown origin)-catalyzed iodination of L-tyrosine assessed as 3,5-diiodo-L-tyrosine formation by HPLC				J Med Chem 51: 7313-7 (2009) Article DOI: 10.1021/jm800894m BindingDB Entry DOI: 10.7270/Q2Z31ZGK
Institute of Science Curated by ChEMBL					More data for this Ligand-Target Pair
Lactoperoxidase (Homo sapiens (Human))	BDBM50275889 (CHEMBL508102 \| carbimazole) Show SMILES CCOC(=O)n1ccn(C)c1=S Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.04E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Science Curated by ChEMBL					Assay Description Inhibition of lactoperoxidase (unknown origin)-catalyzed iodination of L-tyrosine assessed as 3,5-diiodo-L-tyrosine formation by HPLC				J Med Chem 51: 7313-7 (2009) Article DOI: 10.1021/jm800894m BindingDB Entry DOI: 10.7270/Q2Z31ZGK
Institute of Science Curated by ChEMBL					More data for this Ligand-Target Pair
Lactoperoxidase (Homo sapiens (Human))	BDBM50275891 (CHEMBL444464 \| methyl 3-methyl-2-thioxo-2,3-dihydr...) Show SMILES COC(=O)n1ccn(C)c1=S Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.07E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Science Curated by ChEMBL					Assay Description Inhibition of lactoperoxidase (unknown origin)-catalyzed iodination of L-tyrosine assessed as 3,5-diiodo-L-tyrosine formation by HPLC				J Med Chem 51: 7313-7 (2009) Article DOI: 10.1021/jm800894m BindingDB Entry DOI: 10.7270/Q2Z31ZGK
Institute of Science Curated by ChEMBL					More data for this Ligand-Target Pair
Lactoperoxidase (Homo sapiens (Human))	BDBM50241361 (CHEMBL1515 \| METHIMAZOLE \| US9138393, Methimazole ...) Show SMILES Cn1cc[nH]c1=S Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	1.18E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Science Curated by ChEMBL					Assay Description Inhibition of lactoperoxidase (unknown origin)-catalyzed iodination of L-tyrosine assessed as 3,5-diiodo-L-tyrosine formation by HPLC				J Med Chem 51: 7313-7 (2009) Article DOI: 10.1021/jm800894m BindingDB Entry DOI: 10.7270/Q2Z31ZGK
Institute of Science Curated by ChEMBL					More data for this Ligand-Target Pair
Lactoperoxidase (Homo sapiens (Human))	BDBM50275895 (CHEMBL469530 \| methyl 3-ethyl-2-thioxo-2,3-dihydro...) Show SMILES CCn1ccn(C(=O)OC)c1=S Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.96E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Science Curated by ChEMBL					Assay Description Inhibition of lactoperoxidase (unknown origin)-catalyzed iodination of L-tyrosine assessed as 3,5-diiodo-L-tyrosine formation by HPLC				J Med Chem 51: 7313-7 (2009) Article DOI: 10.1021/jm800894m BindingDB Entry DOI: 10.7270/Q2Z31ZGK
Institute of Science Curated by ChEMBL					More data for this Ligand-Target Pair
Lactoperoxidase (Homo sapiens (Human))	BDBM50275892 (CHEMBL507966 \| methyl 3-methyl-2-selenoxo-2,3-dihy...) Show SMILES COC(=O)n1ccn(C)[c]1=[Se] Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.97E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Science Curated by ChEMBL					Assay Description Inhibition of lactoperoxidase (unknown origin)-catalyzed iodination of L-tyrosine assessed as 3,5-diiodo-L-tyrosine formation by HPLC				J Med Chem 51: 7313-7 (2009) Article DOI: 10.1021/jm800894m BindingDB Entry DOI: 10.7270/Q2Z31ZGK
Institute of Science Curated by ChEMBL					More data for this Ligand-Target Pair
Lactoperoxidase (Homo sapiens (Human))	BDBM50275893 (CHEMBL469529 \| ethyl 3-ethyl-2-thioxo-2,3-dihydro-...) Show SMILES CCOC(=O)n1ccn(CC)c1=S Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.05E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Science Curated by ChEMBL					Assay Description Inhibition of lactoperoxidase (unknown origin)-catalyzed iodination of L-tyrosine assessed as 3,5-diiodo-L-tyrosine formation by HPLC				J Med Chem 51: 7313-7 (2009) Article DOI: 10.1021/jm800894m BindingDB Entry DOI: 10.7270/Q2Z31ZGK
Institute of Science Curated by ChEMBL					More data for this Ligand-Target Pair
Lactoperoxidase (Homo sapiens (Human))	BDBM50275894 (CHEMBL446332 \| ethyl 3-ethyl-2-selenoxo-2,3-dihydr...) Show SMILES CCOC(=O)n1ccn(CC)[c]1=[Se] Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.13E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Science Curated by ChEMBL					Assay Description Inhibition of lactoperoxidase (unknown origin)-catalyzed iodination of L-tyrosine assessed as 3,5-diiodo-L-tyrosine formation by HPLC				J Med Chem 51: 7313-7 (2009) Article DOI: 10.1021/jm800894m BindingDB Entry DOI: 10.7270/Q2Z31ZGK
Institute of Science Curated by ChEMBL					More data for this Ligand-Target Pair
Lactoperoxidase (Homo sapiens (Human))	BDBM50275944 (CHEMBL459114 \| methyl 3-ethyl-2-selenoxo-2,3-dihyd...) Show SMILES CCn1ccn(C(=O)OC)[c]1=[Se] Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.53E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Science Curated by ChEMBL					Assay Description Inhibition of lactoperoxidase (unknown origin)-catalyzed iodination of L-tyrosine assessed as 3,5-diiodo-L-tyrosine formation by HPLC				J Med Chem 51: 7313-7 (2009) Article DOI: 10.1021/jm800894m BindingDB Entry DOI: 10.7270/Q2Z31ZGK
Institute of Science Curated by ChEMBL					More data for this Ligand-Target Pair
Lactoperoxidase (Homo sapiens (Human))	BDBM50554035 (CHEMBL4790231) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	>6.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of LPO (unknown origin)				Citation and Details Article DOI: 10.1016/j.bmc.2020.115723 BindingDB Entry DOI: 10.7270/Q21Z4829
TBA					More data for this Ligand-Target Pair
Lactoperoxidase (Homo sapiens (Human))	BDBM50554034 (CHEMBL4747269) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	>6.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of LPO (unknown origin)				Citation and Details Article DOI: 10.1016/j.bmc.2020.115723 BindingDB Entry DOI: 10.7270/Q21Z4829
TBA					More data for this Ligand-Target Pair
Lactoperoxidase (Homo sapiens (Human))	BDBM50106515 (7-Benzyloxy-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-y...) Show SMILES Nc1nc(OCc2ccccc2)c2[nH]nnc2n1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human LPO assessed as reduction in H2O2 catalyzed 3,5-iodo tyrosine formation from 3-iodotyrosine and potassium iodide preincubated for...				ACS Med Chem Lett 9: 1175-1180 (2018) Article DOI: 10.1021/acsmedchemlett.8b00308 BindingDB Entry DOI: 10.7270/Q2W0997Z
					More data for this Ligand-Target Pair