Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Nitroreductase NfsA (Escherichia coli O157:H7) | BDBM50057441 (2-[Bis-(2-iodo-ethyl)-amino]-3,5-dinitro-benzamide...) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Cancer Research Curated by ChEMBL | Assay Description Cytotoxicity in T79-A3 (NR-positive) cell lines | J Med Chem 40: 1270-5 (1997) Article DOI: 10.1021/jm960794l BindingDB Entry DOI: 10.7270/Q26Q1WCS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nitroreductase NfsA (Escherichia coli O157:H7) | BDBM50057437 (2-[Bis-(2-bromo-ethyl)-amino]-3,5-dinitro-benzamid...) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Cancer Research Curated by ChEMBL | Assay Description Cytotoxicity in T79-A3 (NR-positive) cell lines | J Med Chem 40: 1270-5 (1997) Article DOI: 10.1021/jm960794l BindingDB Entry DOI: 10.7270/Q26Q1WCS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nitroreductase NfsA (Escherichia coli O157:H7) | BDBM50039130 (5-(bis(2-iodoethyl)amino)-2,4-dinitrobenzamide | 5...) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 230 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Cancer Research Curated by ChEMBL | Assay Description Cytotoxicity in T79-A3 (NR-positive) cell lines | J Med Chem 40: 1270-5 (1997) Article DOI: 10.1021/jm960794l BindingDB Entry DOI: 10.7270/Q26Q1WCS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nitroreductase NfsA (Escherichia coli O157:H7) | BDBM50039133 (5-(bis(2-bromoethyl)amino)-2,4-dinitrobenzamide | ...) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Cancer Research Curated by ChEMBL | Assay Description Cytotoxicity in T79-A3 (NR-positive) cell lines | J Med Chem 40: 1270-5 (1997) Article DOI: 10.1021/jm960794l BindingDB Entry DOI: 10.7270/Q26Q1WCS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nitroreductase NfsA (Escherichia coli O157:H7) | BDBM50004681 (5-aziridin-1-yl-2,4-dinitro-benzamide | 5-aziridin...) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 890 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Cancer Research Curated by ChEMBL | Assay Description Cytotoxicity in T79-A3 (NR-positive) cell lines | J Med Chem 40: 1270-5 (1997) Article DOI: 10.1021/jm960794l BindingDB Entry DOI: 10.7270/Q26Q1WCS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nitroreductase NfsA (Escherichia coli O157:H7) | BDBM50057444 (5-(bis(2-iodoethyl)amino)-N-(2,3-dihydroxypropyl)-...) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Cancer Research Curated by ChEMBL | Assay Description Cytotoxicity in T79-A3 (NR-positive) cell lines | J Med Chem 40: 1270-5 (1997) Article DOI: 10.1021/jm960794l BindingDB Entry DOI: 10.7270/Q26Q1WCS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nitroreductase NfsA (Escherichia coli O157:H7) | BDBM50057438 (5-[(2-Chloro-ethyl)-(2-methanesulfonyl-ethyl)-amin...) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Cancer Research Curated by ChEMBL | Assay Description Cytotoxicity in T79-A3 (NR-positive) cell lines | J Med Chem 40: 1270-5 (1997) Article DOI: 10.1021/jm960794l BindingDB Entry DOI: 10.7270/Q26Q1WCS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nitroreductase NfsA (Escherichia coli O157:H7) | BDBM50057440 (2-[Bis-(2-iodo-ethyl)-amino]-N-(2,3-dihydroxy-prop...) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Cancer Research Curated by ChEMBL | Assay Description Cytotoxicity in T79-A3 (NR-positive) cell lines | J Med Chem 40: 1270-5 (1997) Article DOI: 10.1021/jm960794l BindingDB Entry DOI: 10.7270/Q26Q1WCS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nitroreductase NfsA (Escherichia coli O157:H7) | BDBM50051698 (2-[Bis-(2-chloro-ethyl)-amino]-3,5-dinitro-benzami...) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 7.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Cancer Research Curated by ChEMBL | Assay Description Cytotoxicity in T79-A3 (NR-positive) cell lines | J Med Chem 40: 1270-5 (1997) Article DOI: 10.1021/jm960794l BindingDB Entry DOI: 10.7270/Q26Q1WCS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nitroreductase NfsA (Escherichia coli O157:H7) | BDBM50057443 (5-[Bis-(2-methanesulfonyl-ethyl)-amino]-2,4-dinitr...) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Cancer Research Curated by ChEMBL | Assay Description Cytotoxicity in T79-A3 (NR-positive) cell lines | J Med Chem 40: 1270-5 (1997) Article DOI: 10.1021/jm960794l BindingDB Entry DOI: 10.7270/Q26Q1WCS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nitroreductase NfsA (Escherichia coli O157:H7) | BDBM50051697 (2-[Bis-(2-chloro-ethyl)-amino]-N-(2,3-dihydroxy-pr...) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Cancer Research Curated by ChEMBL | Assay Description Cytotoxicity in T79-A3 (NR-positive) cell lines | J Med Chem 40: 1270-5 (1997) Article DOI: 10.1021/jm960794l BindingDB Entry DOI: 10.7270/Q26Q1WCS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nitroreductase NfsA (Escherichia coli O157:H7) | BDBM50004694 (5-(bis(2-chloroethyl)amino)-2,4-dinitrobenzamide |...) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Cancer Research Curated by ChEMBL | Assay Description Cytotoxicity in T79-A3 (NR-positive) cell lines | J Med Chem 40: 1270-5 (1997) Article DOI: 10.1021/jm960794l BindingDB Entry DOI: 10.7270/Q26Q1WCS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nitroreductase NfsA (Escherichia coli O157:H7) | BDBM50057442 (5-(bis(2-chloroethyl)amino)-4-(methylsulfonyl)-2-n...) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Cancer Research Curated by ChEMBL | Assay Description Cytotoxicity in T79-A3 (NR-positive) cell lines | J Med Chem 40: 1270-5 (1997) Article DOI: 10.1021/jm960794l BindingDB Entry DOI: 10.7270/Q26Q1WCS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nitroreductase NfsA (Escherichia coli O157:H7) | BDBM50039125 (5-(bis(2-chloroethyl)amino)-N-(2,3-dihydroxypropyl...) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 8.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Cancer Research Curated by ChEMBL | Assay Description Cytotoxicity in T79-A3 (NR-positive) cell lines | J Med Chem 40: 1270-5 (1997) Article DOI: 10.1021/jm960794l BindingDB Entry DOI: 10.7270/Q26Q1WCS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nitroreductase NfsA (Escherichia coli O157:H7) | BDBM50057439 (Bis-(2-chloro-ethyl)-(5-nitro-thiazol-2-yl)-amine ...) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.07E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Cancer Research Curated by ChEMBL | Assay Description Cytotoxicity in T79-A3 (NR-positive) cell lines | J Med Chem 40: 1270-5 (1997) Article DOI: 10.1021/jm960794l BindingDB Entry DOI: 10.7270/Q26Q1WCS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nitroreductase NfsA (Escherichia coli O157:H7) | BDBM50051701 (3-[Bis-(2-chloro-ethyl)-amino]-N-(2-dimethylamino-...) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 8.95E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Cancer Research Curated by ChEMBL | Assay Description Cytotoxicity in T79-A3 (NR-positive) cell lines | J Med Chem 40: 1270-5 (1997) Article DOI: 10.1021/jm960794l BindingDB Entry DOI: 10.7270/Q26Q1WCS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nitroreductase NfsA (Escherichia coli O157:H7) | BDBM50051707 (3-[Bis-(2-chloro-ethyl)-amino]-2,6-dinitro-benzami...) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Cancer Research Curated by ChEMBL | Assay Description Cytotoxicity in T79-A3 (NR-positive) cell lines | J Med Chem 40: 1270-5 (1997) Article DOI: 10.1021/jm960794l BindingDB Entry DOI: 10.7270/Q26Q1WCS | |||||||||||
More data for this Ligand-Target Pair |