Compile Data Set for Download or QSAR

Found 8 hits Enz. Inhib. hit(s) with Target = 'Neuronal acetylcholine receptor subunit beta-4' AND taxid = 10116   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor subunit beta-4 (Rattus norvegicus (Rat))	BDBM50049757 (()-2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]h...) Show SMILES Clc1ccc(cn1)C1CC2CCC1N2 |TLB:4:7:11.10:13| Show InChI InChI=1S/C11H13ClN2/c12-11-4-1-7(6-13-11)9-5-8-2-3-10(9)14-8/h1,4,6,8-10,14H,2-3,5H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	PubMed	0.0200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut f£r Pharmazeutische Chemie der Philipps-Universit£t Marburg Curated by ChEMBL					Assay Description Binding affinity to Nicotinic acetylcholine receptor alpha3-beta4 using +/-[3H]epibatidine as radioligand in pig adrenal gland				J Med Chem 45: 1064-72 (2002) BindingDB Entry DOI: 10.7270/Q2J96736
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit beta-4 (Rattus norvegicus (Rat))	BDBM50110258 ((6S)-2-(6-chloropyridin-3-yl)-9-azabicyclo[4.2.1]n...) Show SMILES Clc1ccc(cn1)C1=CCC[C@H]2CCC1N2 |t:8,THB:4:7:15:13.12| Show InChI InChI=1S/C13H15ClN2/c14-13-7-4-9(8-15-13)11-3-1-2-10-5-6-12(11)16-10/h3-4,7-8,10,12,16H,1-2,5-6H2/t10-,12?/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut f£r Pharmazeutische Chemie der Philipps-Universit£t Marburg Curated by ChEMBL					Assay Description Binding affinity to Nicotinic acetylcholine receptor alpha3-beta4 using +/-[3H]epibatidine as radioligand in pig adrenal gland				J Med Chem 45: 1064-72 (2002) BindingDB Entry DOI: 10.7270/Q2J96736
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit beta-4 (Rattus norvegicus (Rat))	BDBM50110262 (2-Pyridazin-4-yl-9-aza-bicyclo[4.2.1]non-2-ene | C...) Show SMILES C1CC2N[C@H]1CCC=C2c1ccnnc1 |c:8,THB:9:8:3:1.0| Show InChI InChI=1S/C12H15N3/c1-2-10-4-5-12(15-10)11(3-1)9-6-7-13-14-8-9/h3,6-8,10,12,15H,1-2,4-5H2/t10-,12?/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut f£r Pharmazeutische Chemie der Philipps-Universit£t Marburg Curated by ChEMBL					Assay Description Binding affinity to Nicotinic acetylcholine receptor alpha3-beta4 using +/-[3H]epibatidine as radioligand in pig adrenal gland				J Med Chem 45: 1064-72 (2002) BindingDB Entry DOI: 10.7270/Q2J96736
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit beta-4 (Rattus norvegicus (Rat))	BDBM50110260 (2-Pyridin-3-yl-9-aza-bicyclo[4.2.1]non-2-ene | 2-P...) Show SMILES C1CC2N[C@H]1CCC=C2c1cccnc1 |c:8,THB:9:8:3:1.0| Show InChI InChI=1S/C13H16N2/c1-4-11-6-7-13(15-11)12(5-1)10-3-2-8-14-9-10/h2-3,5,8-9,11,13,15H,1,4,6-7H2/t11-,13?/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut f£r Pharmazeutische Chemie der Philipps-Universit£t Marburg Curated by ChEMBL					Assay Description Binding affinity to Nicotinic acetylcholine receptor alpha3-beta4 using +/-[3H]epibatidine as radioligand in pig adrenal gland				J Med Chem 45: 1064-72 (2002) BindingDB Entry DOI: 10.7270/Q2J96736
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit beta-4 (Rattus norvegicus (Rat))	BDBM50023330 (1-(9-Aza-bicyclo[4.2.1]non-2-en-2-yl)-ethanone | 1...) Show SMILES CC(=O)C1=CCCC2CCC1N2 |t:3,THB:1:3:11:9.8| Show InChI InChI=1S/C10H15NO/c1-7(12)9-4-2-3-8-5-6-10(9)11-8/h4,8,10-11H,2-3,5-6H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut f£r Pharmazeutische Chemie der Philipps-Universit£t Marburg Curated by ChEMBL					Assay Description Binding affinity to Nicotinic acetylcholine receptor alpha3-beta4 using +/-[3H]epibatidine as radioligand in pig adrenal gland				J Med Chem 45: 1064-72 (2002) BindingDB Entry DOI: 10.7270/Q2J96736
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit beta-4 (Rattus norvegicus (Rat))	BDBM50110259 (2-Pyrimidin-5-yl-9-aza-bicyclo[4.2.1]non-2-ene | C...) Show SMILES C1CC2N[C@H]1CCC=C2c1cncnc1 |c:8,THB:9:8:3:1.0| Show InChI InChI=1S/C12H15N3/c1-2-10-4-5-12(15-10)11(3-1)9-6-13-8-14-7-9/h3,6-8,10,12,15H,1-2,4-5H2/t10-,12?/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut f£r Pharmazeutische Chemie der Philipps-Universit£t Marburg Curated by ChEMBL					Assay Description Binding affinity to Nicotinic acetylcholine receptor alpha3-beta4 using +/-[3H]epibatidine as radioligand in pig adrenal gland				J Med Chem 45: 1064-72 (2002) BindingDB Entry DOI: 10.7270/Q2J96736
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit beta-4 (Rattus norvegicus (Rat))	BDBM82070 (CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...) Show SMILES CN1CCC[C@H]1c1cccnc1 |r| Show InChI InChI=1S/C10H14N2/c1-12-7-3-5-10(12)9-4-2-6-11-8-9/h2,4,6,8,10H,3,5,7H2,1H3/t10-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase KEGG PC cid PC sid PDB UniChem Similars	PubMed	73	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut f£r Pharmazeutische Chemie der Philipps-Universit£t Marburg Curated by ChEMBL					Assay Description Binding affinity to Nicotinic acetylcholine receptor alpha3-beta4 using +/-[3H]epibatidine as radioligand in pig adrenal gland				J Med Chem 45: 1064-72 (2002) BindingDB Entry DOI: 10.7270/Q2J96736
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit beta-4 (Rattus norvegicus (Rat))	BDBM50110263 (2-Pyrazin-2-yl-9-aza-bicyclo[4.2.1]non-2-ene | CHE...) Show SMILES C1CC2N[C@H]1CCC=C2c1cnccn1 |c:8,THB:9:8:3:1.0| Show InChI InChI=1S/C12H15N3/c1-2-9-4-5-11(15-9)10(3-1)12-8-13-6-7-14-12/h3,6-9,11,15H,1-2,4-5H2/t9-,11?/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	259	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut f£r Pharmazeutische Chemie der Philipps-Universit£t Marburg Curated by ChEMBL					Assay Description Binding affinity to Nicotinic acetylcholine receptor alpha3-beta4 using +/-[3H]epibatidine as radioligand in pig adrenal gland				J Med Chem 45: 1064-72 (2002) BindingDB Entry DOI: 10.7270/Q2J96736
					More data for this Ligand-Target Pair