BindingDB PrimarySearch

Found 6 hits Enz. Inhib. hit(s) with Target = 'Potassium channel subfamily K member 2' AND taxid = 9913
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Potassium two pore domain channel subfamily K member 2 (Bos taurus)	BDBM50088383 (Amlodipine \| CHEBI:2668 \| Norvasc) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Clermont Auvergne Curated by ChEMBL					Assay Description Activation of bovine TREK1 expressed in AZT cells assessed as reduction in channel currents				J Med Chem 59: 5149-57 (2016) Article DOI: 10.1021/acs.jmedchem.5b00671 BindingDB Entry DOI: 10.7270/Q2319XSS
Universit£ Clermont Auvergne Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium two pore domain channel subfamily K member 2 (Bos taurus)	BDBM50180663 (CHEBI:7572 \| CHEMBL1275655) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL DrugBank KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	750	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Clermont Auvergne Curated by ChEMBL					Assay Description Activation of bovine TREK1 expressed in AZT cells assessed as reduction in channel currents				J Med Chem 59: 5149-57 (2016) Article DOI: 10.1021/acs.jmedchem.5b00671 BindingDB Entry DOI: 10.7270/Q2319XSS
Universit£ Clermont Auvergne Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium two pore domain channel subfamily K member 2 (Bos taurus)	BDBM50067040 (((E,E)-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-hept...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	930	n/a	n/a	n/a	n/a	n/a	n/a
The Ohio State University College of Medicine and Public Health Curated by ChEMBL					Assay Description Inhibition of TREK-1 K(+) channel in bovine AZF cells				J Nat Prod 72: 1533-7 (2009) Article DOI: 10.1021/np900227x BindingDB Entry DOI: 10.7270/Q2F18ZTC
					More data for this Ligand-Target Pair
Potassium two pore domain channel subfamily K member 2 (Bos taurus)	BDBM22988 ((5Z,8Z,11Z,14Z)-N-(2-hydroxyethyl)icosa-5,8,11,14-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Clermont Auvergne Curated by ChEMBL					Assay Description Activation of bovine TREK1 expressed in AZT cells assessed as reduction in channel currents				J Med Chem 59: 5149-57 (2016) Article DOI: 10.1021/acs.jmedchem.5b00671 BindingDB Entry DOI: 10.7270/Q2319XSS
Universit£ Clermont Auvergne Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium two pore domain channel subfamily K member 2 (Bos taurus)	BDBM50017702 (1-(bis(4-fluorophenyl)methyl)-4-cinnamylpiperazine...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Clermont Auvergne Curated by ChEMBL					Assay Description Activation of bovine TREK1 expressed in AZT cells assessed as reduction in channel currents				J Med Chem 59: 5149-57 (2016) Article DOI: 10.1021/acs.jmedchem.5b00671 BindingDB Entry DOI: 10.7270/Q2319XSS
Universit£ Clermont Auvergne Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium two pore domain channel subfamily K member 2 (Bos taurus)	BDBM50101817 (Adalat \| Adalat Cc \| Afeditab Cr \| BAY-A-1040 \| CH...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Clermont Auvergne Curated by ChEMBL					Assay Description Activation of bovine TREK1 expressed in AZT cells assessed as reduction in channel currents				J Med Chem 59: 5149-57 (2016) Article DOI: 10.1021/acs.jmedchem.5b00671 BindingDB Entry DOI: 10.7270/Q2319XSS
Universit£ Clermont Auvergne Curated by ChEMBL					More data for this Ligand-Target Pair