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Compile Data Set for Download or QSAR

Found 341 hits Enz. Inhib. hit(s) with Target = 'Presequence protease, mitochondrial' AND taxid = 9606   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Presequence protease, mitochondrial


(Homo sapiens (Human))
BDBM622271
PNG
((R)-N-(2-(4-cyanothiazolidin-3-yl)-2-oxoethyl)-7-m...)
Show SMILES Cc1ccc2c(ccnc2c1)C(=O)NCC(=O)N1CSC[C@H]1C#N |r|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 5.20n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Presequence protease, mitochondrial


(Homo sapiens (Human))
BDBM622271
PNG
((R)-N-(2-(4-cyanothiazolidin-3-yl)-2-oxoethyl)-7-m...)
Show SMILES Cc1ccc2c(ccnc2c1)C(=O)NCC(=O)N1CSC[C@H]1C#N |r|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 5.20n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Presequence protease, mitochondrial


(Homo sapiens (Human))
BDBM622272
PNG
((R)-N-(2-(4-cyanothiazolidin-3-yl)-2-oxoethyl)-qui...)
Show SMILES O=C(CNC(=O)c1ccnc2ccccc12)N1CSC[C@H]1C#N |r|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 7.10n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Presequence protease, mitochondrial


(Homo sapiens (Human))
BDBM622272
PNG
((R)-N-(2-(4-cyanothiazolidin-3-yl)-2-oxoethyl)-qui...)
Show SMILES O=C(CNC(=O)c1ccnc2ccccc12)N1CSC[C@H]1C#N |r|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 7.10n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Presequence protease, mitochondrial (PREP)


(Homo sapiens (Human))
BDBM514515
PNG
(US11096924, DASH-inhibitors 3102 C | US11583516, C...)
Show SMILES N[C@H](C(=O)N1CCC[C@H]1B(O)O)C12CC3CC(CC(Cl)(C3)C1)C2 |r,TLB:1:12:20:16.15.17,22:12:20:16.15.17,15:16:21:20.14.13,THB:22:16:20:21.12.13,15:14:21:16.22.17|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 15n/an/an/an/an/an/a


TBA

Assay Description
Materials: Enzymes Recombinant human DPPIV (R&D Systems, Cat. No. 1180-SE). Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527). Recombin...


Citation and Details

BindingDB Entry DOI: 10.7270/Q27P93BT
More data for this
Ligand-Target Pair
Presequence protease, mitochondrial (PREP)


(Homo sapiens (Human))
BDBM514521
PNG
(US11096924, DASH-inhibitors 4268 | US11583516, Cmp...)
Show SMILES CC(C)(F)[C@H](N)C(=O)N1CCC[C@H]1B(O)O |r|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 23n/an/an/an/an/an/a


TBA

Assay Description
Materials: Enzymes Recombinant human DPPIV (R&D Systems, Cat. No. 1180-SE). Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527). Recombin...


Citation and Details

BindingDB Entry DOI: 10.7270/Q27P93BT
More data for this
Ligand-Target Pair
Presequence protease, mitochondrial


(Homo sapiens (Human))
BDBM622160
PNG
(US20230312550, Example 120)
Show SMILES Fc1ccc2n(ccc2c1)-c1ccc2nccc(C(=O)NCC(=O)N3CSC[C@H]3C#N)c2c1 |r|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 25n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Presequence protease, mitochondrial


(Homo sapiens (Human))
BDBM622099
PNG
(US20230312550, Example 59)
Show SMILES F[C@@H]1CCCCN(C1)c1ccc2nccc(C(=O)NCC(=O)N3CSC[C@H]3C#N)c2c1 |r|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 30n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Presequence protease, mitochondrial (PREP)


(Homo sapiens (Human))
BDBM514516
PNG
(US11096924, DASH-inhibitors 4175 CH | US11583516, ...)
Show SMILES CC1(CCCCC1)[C@H](N)C(=O)N1CCC[C@H]1B(O)O |r|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 34n/an/an/an/an/an/a


TBA

Assay Description
Materials: Enzymes Recombinant human DPPIV (R&D Systems, Cat. No. 1180-SE). Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527). Recombin...


Citation and Details

BindingDB Entry DOI: 10.7270/Q27P93BT
More data for this
Ligand-Target Pair
Presequence protease, mitochondrial


(Homo sapiens (Human))
BDBM622227
PNG
(US20230312550, Example 187)
Show SMILES Clc1ccc(CC2CN(C2)c2ccc3nccc(C(=O)NCC(=O)N4CSC[C@H]4C#N)c3c2)cc1 |r|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 38n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Presequence protease, mitochondrial (PREP)


(Homo sapiens (Human))
BDBM514514
PNG
(US11096924, DASH-inhibitors (formerly 3102 A 2C) |...)
Show SMILES N[C@H](C(=O)N1CCC[C@H]1B(O)O)C12CC3CC(CC(C3)C1)C2 |r,TLB:19:18:21:15.14.13,19:14:21:18.20.17,THB:1:12:15:18.19.17,20:18:15:21.12.13,20:12:15:18.19.17|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 42n/an/an/an/an/an/a


TBA

Assay Description
Materials: Enzymes Recombinant human DPPIV (R&D Systems, Cat. No. 1180-SE). Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527). Recombin...


Citation and Details

BindingDB Entry DOI: 10.7270/Q27P93BT
More data for this
Ligand-Target Pair
Presequence protease, mitochondrial (PREP)


(Homo sapiens (Human))
BDBM514532
PNG
(US11096924, DASH-inhibitors 3102 A | US11583516, C...)
Show SMILES N[C@H](C(=O)N1CCC[C@H]1B(O)O)C12CC3CC(CC(O)(C3)C1)C2 |r,TLB:1:12:20:16.15.17,22:12:20:16.15.17,15:16:21:20.14.13,THB:22:16:20:21.12.13,15:14:21:16.22.17|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 49n/an/an/an/an/an/a


TBA

Assay Description
Materials: Enzymes Recombinant human DPPIV (R&D Systems, Cat. No. 1180-SE). Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527). Recombin...


Citation and Details

BindingDB Entry DOI: 10.7270/Q27P93BT
More data for this
Ligand-Target Pair
Presequence protease, mitochondrial (PREP)


(Homo sapiens (Human))
BDBM514530
PNG
(US11096924, DASH-inhibitors 4949 | US11583516, Cmp...)
Show SMILES N[C@H](C(=O)N1CCC[C@H]1B(O)O)C1(CC1)C(F)(F)F |r|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 58n/an/an/an/an/an/a


TBA

Assay Description
Materials: Enzymes Recombinant human DPPIV (R&D Systems, Cat. No. 1180-SE). Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527). Recombin...


Citation and Details

BindingDB Entry DOI: 10.7270/Q27P93BT
More data for this
Ligand-Target Pair
Presequence protease, mitochondrial (PREP)


(Homo sapiens (Human))
BDBM514520
PNG
(US11096924, DASH-inhibitors 4175 CP | US11583516, ...)
Show SMILES CC1(CCCC1)[C@H](N)C(=O)N1CCC[C@H]1B(O)O |r|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 68n/an/an/an/an/an/a


TBA

Assay Description
Materials: Enzymes Recombinant human DPPIV (R&D Systems, Cat. No. 1180-SE). Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527). Recombin...


Citation and Details

BindingDB Entry DOI: 10.7270/Q27P93BT
More data for this
Ligand-Target Pair
Presequence protease, mitochondrial


(Homo sapiens (Human))
BDBM622159
PNG
(US20230312550, Example 119)
Show SMILES Fc1cc(F)c2ccn(-c3ccc4nccc(C(=O)NCC(=O)N5CSC[C@H]5C#N)c4c3)c2c1 |r|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 76n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Presequence protease, mitochondrial


(Homo sapiens (Human))
BDBM622236
PNG
(US20230312550, Example 196)
Show SMILES O=C(CNC(=O)c1ccnc2ccc(cc12)-c1ccn[nH]1)N1CSC[C@H]1C#N |r|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 84n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Presequence protease, mitochondrial


(Homo sapiens (Human))
BDBM622100
PNG
(US20230312550, Example 60)
Show SMILES F[C@H]1CCCCN(C1)c1ccc2nccc(C(=O)NCC(=O)N3CSC[C@H]3C#N)c2c1 |r|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 86n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Presequence protease, mitochondrial


(Homo sapiens (Human))
BDBM622263
PNG
(US20230312550, Example 223)
Show SMILES FC1(CCN(CC1)c1ccc2nccc(C(=O)NCC(=O)N3CSC[C@H]3C#N)c2c1)c1ccccc1 |r|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 86n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Presequence protease, mitochondrial


(Homo sapiens (Human))
BDBM622214
PNG
(US20230312550, Example 174)
Show SMILES Cn1nccc1-c1ccc2nccc(C(=O)NCC(=O)N3CSC[C@H]3C#N)c2c1 |r|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 87n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Presequence protease, mitochondrial


(Homo sapiens (Human))
BDBM622161
PNG
(US20230312550, Example 121)
Show SMILES Cc1ccn(c1)-c1ccc2nccc(C(=O)NCC(=O)N3CSC[C@H]3C#N)c2c1 |r|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 88n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Presequence protease, mitochondrial


(Homo sapiens (Human))
BDBM622061
PNG
(US20230312550, Example 21)
Show SMILES FC1CN(C1)c1ccc2nccc(C(=O)NCC(=O)N3CSC[C@H]3C#N)c2c1 |r|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 93n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Presequence protease, mitochondrial


(Homo sapiens (Human))
BDBM622105
PNG
(US20230312550, Example 65)
Show SMILES C[C@H]1CCCN1c1ccc2nccc(C(=O)NCC(=O)N3CSC[C@H]3C#N)c2c1 |r|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 100n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Presequence protease, mitochondrial


(Homo sapiens (Human))
BDBM622086
PNG
(US20230312550, Example 46)
Show SMILES O=C(CNC(=O)c1ccnc2ccc(cc12)N1CCCC2(CC2)C1)N1CSC[C@H]1C#N |r|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 110n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Presequence protease, mitochondrial


(Homo sapiens (Human))
BDBM622168
PNG
(US20230312550, Example 128)
Show SMILES Cc1ncccc1-c1ccc2nccc(C(=O)NCC(=O)N3CSC[C@H]3C#N)c2c1 |r|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 110n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Presequence protease, mitochondrial


(Homo sapiens (Human))
BDBM622251
PNG
(US20230312550, Example 211)
Show SMILES C[C@@H]1CCCN1c1ccc2nccc(C(=O)NCC(=O)N3CSC[C@H]3C#N)c2c1 |r|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 110n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Presequence protease, mitochondrial


(Homo sapiens (Human))
BDBM622218
PNG
(US20230312550, Example 178)
Show SMILES COc1ccc(cn1)-c1ccc2nccc(C(=O)NCC(=O)N3CSC[C@H]3C#N)c2c1 |r|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 120n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Presequence protease, mitochondrial


(Homo sapiens (Human))
BDBM622165
PNG
(US20230312550, Example 125)
Show SMILES Fc1ccc(nc1)-c1ccc2nccc(C(=O)NCC(=O)N3CSC[C@H]3C#N)c2c1 |r|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 120n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Presequence protease, mitochondrial


(Homo sapiens (Human))
BDBM622155
PNG
(US20230312550, Example 115)
Show SMILES O=C(CNC(=O)c1ccnc2ccc(cc12)-n1cc2CCCCc2n1)N1CSC[C@H]1C#N |r|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 130n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Presequence protease, mitochondrial


(Homo sapiens (Human))
BDBM622167
PNG
(US20230312550, Example 127)
Show SMILES O=C(CNC(=O)c1ccnc2ccc(cc12)-c1cncnc1)N1CSC[C@H]1C#N |r|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 130n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Presequence protease, mitochondrial


(Homo sapiens (Human))
BDBM622240
PNG
(US20230312550, Example 200)
Show SMILES O=C(CNC(=O)c1ccnc2ccc(cc12)N1CCC[C@H]1C1CC1)N1CSC[C@H]1C#N |r|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 130n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Presequence protease, mitochondrial


(Homo sapiens (Human))
BDBM622225
PNG
(US20230312550, Example 185)
Show SMILES Fc1ccc(cc1)C1CN(C1)c1ccc2nccc(C(=O)NCC(=O)N3CSC[C@H]3C#N)c2c1 |r|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 130n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Presequence protease, mitochondrial


(Homo sapiens (Human))
BDBM622091
PNG
(US20230312550, Example 51)
Show SMILES F[C@H]1CCN(C1)c1ccc2nccc(C(=O)NCC(=O)N3CSC[C@H]3C#N)c2c1 |r|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 130n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Presequence protease, mitochondrial


(Homo sapiens (Human))
BDBM622051
PNG
(US20230312550, Example 11)
Show SMILES O=C(CNC(=O)c1ccnc2ccc(cc12)N1CCCC1=O)N1CSC[C@H]1C#N |r|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 140n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Presequence protease, mitochondrial


(Homo sapiens (Human))
BDBM622223
PNG
(US20230312550, Example 183)
Show SMILES Cc1ccc(cc1)C1CN(C1)c1ccc2nccc(C(=O)NCC(=O)N3CSC[C@H]3C#N)c2c1 |r|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 140n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Presequence protease, mitochondrial


(Homo sapiens (Human))
BDBM622226
PNG
(US20230312550, Example 186)
Show SMILES Cc1cccc(c1)C1CN(C1)c1ccc2nccc(C(=O)NCC(=O)N3CSC[C@H]3C#N)c2c1 |r|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 150n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Presequence protease, mitochondrial


(Homo sapiens (Human))
BDBM622057
PNG
(US20230312550, Example 17)
Show SMILES O=C(CNC(=O)c1ccnc2ccc(cc12)N1CC2(CCC2)C1)N1CSC[C@H]1C#N |r|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 160n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Presequence protease, mitochondrial


(Homo sapiens (Human))
BDBM622059
PNG
(US20230312550, Example 19)
Show SMILES O=C(CNC(=O)c1ccnc2ccc(cc12)N1CCC11CCC1)N1CSC[C@H]1C#N |r|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 160n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Presequence protease, mitochondrial


(Homo sapiens (Human))
BDBM622063
PNG
(US20230312550, Example 23)
Show SMILES FC1(F)CN(C1)c1ccc2nccc(C(=O)NCC(=O)N3CSC[C@H]3C#N)c2c1 |r|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 160n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Presequence protease, mitochondrial


(Homo sapiens (Human))
BDBM622097
PNG
(US20230312550, Example 57)
Show SMILES CC1(C)CCCN1c1ccc2nccc(C(=O)NCC(=O)N3CSC[C@H]3C#N)c2c1 |r|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 160n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Presequence protease, mitochondrial


(Homo sapiens (Human))
BDBM622140
PNG
(US20230312550, Example 100)
Show SMILES C[C@H]1COC[C@@H](C)N1c1cc2c(ccnc2cc1Br)C(=O)NCC(=O)N1CSC[C@H]1C#N |r|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 170n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Presequence protease, mitochondrial


(Homo sapiens (Human))
BDBM622239
PNG
(US20230312550, Example 199)
Show SMILES O=C(CNC(=O)c1ccnc2ccc(cc12)N1CCC[C@@H]1C1CC1)N1CSC[C@H]1C#N |r|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 170n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Presequence protease, mitochondrial


(Homo sapiens (Human))
BDBM622088
PNG
(US20230312550, Example 48)
Show SMILES CC1(C)CCN(C1)c1ccc2nccc(C(=O)NCC(=O)N3CSC[C@H]3C#N)c2c1 |r|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 170n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Presequence protease, mitochondrial


(Homo sapiens (Human))
BDBM622093
PNG
(US20230312550, Example 53)
Show SMILES O=C(CNC(=O)c1ccnc2ccc(cc12)N1CC2CCCC2C1)N1CSC[C@H]1C#N |r|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 170n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Presequence protease, mitochondrial


(Homo sapiens (Human))
BDBM622157
PNG
(US20230312550, Example 117)
Show SMILES CC1(C)CCc2cn(nc12)-c1ccc2nccc(C(=O)NCC(=O)N3CSC[C@H]3C#N)c2c1 |r|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 170n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Presequence protease, mitochondrial


(Homo sapiens (Human))
BDBM622098
PNG
(US20230312550, Example 58)
Show SMILES FC[C@H]1CC2(CC2)CN1c1ccc2nccc(C(=O)NCC(=O)N3CSC[C@H]3C#N)c2c1 |r|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 180n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Presequence protease, mitochondrial


(Homo sapiens (Human))
BDBM622085
PNG
(US20230312550, Example 45)
Show SMILES FC[C@@H]1CCCCN1c1ccc2nccc(C(=O)NCC(=O)N3CSC[C@H]3C#N)c2c1 |r|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 190n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Presequence protease, mitochondrial


(Homo sapiens (Human))
BDBM622256
PNG
(US20230312550, Example 216)
Show SMILES Cc1noc(C)c1-c1ccc2nccc(C(=O)NCC(=O)N3CSC[C@H]3C#N)c2c1 |r|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 190n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Presequence protease, mitochondrial (PREP)


(Homo sapiens (Human))
BDBM514555
PNG
(US11096924, DASH-inhibitors 4367 | US11583516, Cmp...)
Show SMILES CC1(CC1)[C@H](N)C(=O)N1CCC[C@H]1B(O)O |r|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 200n/an/an/an/an/an/a


TBA

Assay Description
Materials: Enzymes Recombinant human DPPIV (R&D Systems, Cat. No. 1180-SE). Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527). Recombin...


Citation and Details

BindingDB Entry DOI: 10.7270/Q27P93BT
More data for this
Ligand-Target Pair
Presequence protease, mitochondrial


(Homo sapiens (Human))
BDBM622046
PNG
(US20230312550, Example 6)
Show SMILES O=C(CNC(=O)c1ccnc2ccc(cc12)N1CCOc2ccccc12)N1CSC[C@H]1C#N |r|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 200n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Presequence protease, mitochondrial


(Homo sapiens (Human))
BDBM622232
PNG
(US20230312550, Example 192)
Show SMILES CC(C)C1(O)CCN(CC1)c1ccc2nccc(C(=O)NCC(=O)N3CSC[C@H]3C#N)c2c1 |r|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 200n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
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