BindingDB PrimarySearch

Found 12 hits Enz. Inhib. hit(s) with Target = 'Phosphatidylserine lipase ABHD16A' AND taxid = 9606
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Phosphatidylserine lipase ABHD16A (Homo sapiens (Human))	BDBM24567 ((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of recombinant BAT5 transfected in HEK293T cells by SDS-PAGE using rhodamine-tagged FP probe				Bioorg Med Chem Lett 18: 5838-41 (2008) Article DOI: 10.1016/j.bmcl.2008.06.091 BindingDB Entry DOI: 10.7270/Q2XK8GGZ
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylserine lipase ABHD16A (Homo sapiens (Human))	BDBM50507489 (CHEMBL4564841) Show SMILES COc1nn(-c2ccc(F)cc2)c(=O)o1 Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
University of Helsinki Curated by ChEMBL					Assay Description Inhibition of ABHD16A (unknown origin)				ACS Med Chem Lett 9: 1269-1273 (2018) Article DOI: 10.1021/acsmedchemlett.8b00442 BindingDB Entry DOI: 10.7270/Q2KH0RM7
University of Helsinki Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylserine lipase ABHD16A (Homo sapiens (Human))	BDBM50336546 (CHEMBL1673415 \| Palmostatin B) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	57	n/a	n/a	n/a	n/a	n/a	n/a
University of Helsinki Curated by ChEMBL					Assay Description Reversible inhibition of human ABHD16A expressed in HEK293 cells preincubated for 30 mins followed by 40 fold compound dilution and subsequent 1-LG s...				ACS Med Chem Lett 9: 1269-1273 (2018) Article DOI: 10.1021/acsmedchemlett.8b00442 BindingDB Entry DOI: 10.7270/Q2KH0RM7
University of Helsinki Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylserine lipase ABHD16A (Homo sapiens (Human))	BDBM195603 (KC01) Show SMILES CCCCCCCCCCCCCC1OC(=O)\C1=C/CCCCC(N)=O Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
University of Helsinki Curated by ChEMBL					Assay Description Inhibition of ABHD16A (unknown origin)				ACS Med Chem Lett 9: 1269-1273 (2018) Article DOI: 10.1021/acsmedchemlett.8b00442 BindingDB Entry DOI: 10.7270/Q2KH0RM7
University of Helsinki Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylserine lipase ABHD16A (Homo sapiens (Human))	BDBM50336546 (CHEMBL1673415 \| Palmostatin B) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	99	n/a	n/a	n/a	n/a	n/a	n/a
University of Helsinki Curated by ChEMBL					Assay Description Inhibition of human ABHD16A expressed in HEK293 cells preincubated for 30 mins followed by 1-LG substrate addition and measured after 90 to 120 mins ...				ACS Med Chem Lett 9: 1269-1273 (2018) Article DOI: 10.1021/acsmedchemlett.8b00442 BindingDB Entry DOI: 10.7270/Q2KH0RM7
University of Helsinki Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylserine lipase ABHD16A (Homo sapiens (Human))	BDBM50336546 (CHEMBL1673415 \| Palmostatin B) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
University of Helsinki Curated by ChEMBL					Assay Description Inhibition of ABHD16A (unknown origin)				ACS Med Chem Lett 9: 1269-1273 (2018) Article DOI: 10.1021/acsmedchemlett.8b00442 BindingDB Entry DOI: 10.7270/Q2KH0RM7
University of Helsinki Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylserine lipase ABHD16A (Homo sapiens (Human))	BDBM24567 ((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
University of Helsinki Curated by ChEMBL					Assay Description Inhibition of ABHD16A (unknown origin)				ACS Med Chem Lett 9: 1269-1273 (2018) Article DOI: 10.1021/acsmedchemlett.8b00442 BindingDB Entry DOI: 10.7270/Q2KH0RM7
University of Helsinki Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylserine lipase ABHD16A (Homo sapiens (Human))	BDBM50507488 (CHEMBL4585683) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Helsinki Curated by ChEMBL					Assay Description Inhibition of human ABHD16A expressed in HEK293 cells preincubated for 30 mins followed by 1-LG substrate addition and measured after 90 to 120 mins ...				ACS Med Chem Lett 9: 1269-1273 (2018) Article DOI: 10.1021/acsmedchemlett.8b00442 BindingDB Entry DOI: 10.7270/Q2KH0RM7
University of Helsinki Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylserine lipase ABHD16A (Homo sapiens (Human))	BDBM50507487 (CHEMBL4591378) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Helsinki Curated by ChEMBL					Assay Description Inhibition of human ABHD16A expressed in HEK293 cells preincubated for 30 mins followed by 1-LG substrate addition and measured after 90 to 120 mins ...				ACS Med Chem Lett 9: 1269-1273 (2018) Article DOI: 10.1021/acsmedchemlett.8b00442 BindingDB Entry DOI: 10.7270/Q2KH0RM7
University of Helsinki Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylserine lipase ABHD16A (Homo sapiens (Human))	BDBM50240877 (CHEMBL158897 \| Quinolyl derivatives \| cyclohexanon...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of recombinant BAT5 transfected in HEK293T cells by SDS-PAGE using rhodamine-tagged FP probe				Bioorg Med Chem Lett 18: 5838-41 (2008) Article DOI: 10.1016/j.bmcl.2008.06.091 BindingDB Entry DOI: 10.7270/Q2XK8GGZ
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylserine lipase ABHD16A (Homo sapiens (Human))	BDBM50507487 (CHEMBL4591378) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.16E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Helsinki Curated by ChEMBL					Assay Description Reversible inhibition of human ABHD16A expressed in HEK293 cells preincubated for 30 mins followed by 40 fold compound dilution and subsequent 1-LG s...				ACS Med Chem Lett 9: 1269-1273 (2018) Article DOI: 10.1021/acsmedchemlett.8b00442 BindingDB Entry DOI: 10.7270/Q2KH0RM7
University of Helsinki Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylserine lipase ABHD16A (Homo sapiens (Human))	BDBM50507488 (CHEMBL4585683) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.11E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Helsinki Curated by ChEMBL					Assay Description Reversible inhibition of human ABHD16A expressed in HEK293 cells preincubated for 30 mins followed by 40 fold compound dilution and subsequent 1-LG s...				ACS Med Chem Lett 9: 1269-1273 (2018) Article DOI: 10.1021/acsmedchemlett.8b00442 BindingDB Entry DOI: 10.7270/Q2KH0RM7
University of Helsinki Curated by ChEMBL					More data for this Ligand-Target Pair