Compile Data Set for Download or QSAR

Found 14 hits Enz. Inhib. hit(s) with Target = 'Protein tyrosine phosphatase type IVA 2' AND taxid = 9606   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein tyrosine phosphatase type IVA 2 (Homo sapiens (Human))	BDBM396097 (US10308663, JMS-631-053) Show SMILES N=C1c2sc(cc2C(=O)NC1=O)-c1ccccc1 Show InChI InChI=1S/C13H8N2O2S/c14-10-11-8(12(16)15-13(10)17)6-9(18-11)7-4-2-1-3-5-7/h1-6,14H,(H,15,16,17)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibition of PTP4A2 (unknown origin) expressed in Escherichia coli assessed as reduction in hydrolysis using DIFMUP as substrate incubated for 30 mi...				Bioorg Med Chem Lett 29: 2008-2015 (2019) Article DOI: 10.1016/j.bmcl.2019.06.048 BindingDB Entry DOI: 10.7270/Q2VH5SBF
					More data for this Ligand-Target Pair
Protein tyrosine phosphatase type IVA 2 (Homo sapiens (Human))	BDBM50059084 (CHEMBL3393171 | US10308663, Thienopyridone (5)) Show SMILES Nc1c[nH]c(=O)c2cc(sc12)-c1ccccc1 Show InChI InChI=1S/C13H10N2OS/c14-10-7-15-13(16)9-6-11(17-12(9)10)8-4-2-1-3-5-8/h1-7H,14H2,(H,15,16)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human His6-tagged PRL-2 expressed in Escherichia coli using TAMRA-Thr-Ala-Asp-Ile-Tyr(PO3H2)-Glu-NH2 peptide as substrate by IMAP-FP as...				Citation and Details Article DOI: 10.1016/j.bmcl.2021.127981 BindingDB Entry DOI: 10.7270/Q2NK3JSF
					More data for this Ligand-Target Pair
Protein tyrosine phosphatase type IVA 2 (Homo sapiens (Human))	BDBM50059084 (CHEMBL3393171 | US10308663, Thienopyridone (5)) Show SMILES Nc1c[nH]c(=O)c2cc(sc12)-c1ccccc1 Show InChI InChI=1S/C13H10N2OS/c14-10-7-15-13(16)9-6-11(17-12(9)10)8-4-2-1-3-5-8/h1-7H,14H2,(H,15,16)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	277	n/a	n/a	n/a	n/a	n/a	n/a
European Molecular Biology Laboratory Curated by ChEMBL					Assay Description Inhibition of human PRL2 expressed in Escherichia coli using TAMRA-Thr-Ala-Asp-Ile-Tyr(PO3H2)-Glu-NH2 substrate by immobilized metal ion affinity-bas...				Eur J Med Chem 88: 89-100 (2014) Article DOI: 10.1016/j.ejmech.2014.08.060 BindingDB Entry DOI: 10.7270/Q2FQ9Z8G
					More data for this Ligand-Target Pair
Protein tyrosine phosphatase type IVA 2 (Homo sapiens (Human))	BDBM50059084 (CHEMBL3393171 | US10308663, Thienopyridone (5)) Show SMILES Nc1c[nH]c(=O)c2cc(sc12)-c1ccccc1 Show InChI InChI=1S/C13H10N2OS/c14-10-7-15-13(16)9-6-11(17-12(9)10)8-4-2-1-3-5-8/h1-7H,14H2,(H,15,16)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibition of recombinant human His-6-tagged PTP4A2 expressed in Escherichia coli assessed as increase in polarization using TAMRAThr-Ala-Asp-Ile-Tyr...				Bioorg Med Chem Lett 29: 2008-2015 (2019) Article DOI: 10.1016/j.bmcl.2019.06.048 BindingDB Entry DOI: 10.7270/Q2VH5SBF
					More data for this Ligand-Target Pair
Protein tyrosine phosphatase type IVA 2 (Homo sapiens (Human))	BDBM45440 (4-[5-(4-amidinophenoxy)pentoxy]benzamidine;2-hydro...) Show SMILES NC(=N)c1ccc(OCCCCCOc2ccc(cc2)C(N)=N)cc1 Show InChI InChI=1S/C19H24N4O2/c20-18(21)14-4-8-16(9-5-14)24-12-2-1-3-13-25-17-10-6-15(7-11-17)19(22)23/h4-11H,1-3,12-13H2,(H3,20,21)(H3,22,23)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibition of PTP4A2 (unknown origin)				Bioorg Med Chem Lett 29: 2008-2015 (2019) Article DOI: 10.1016/j.bmcl.2019.06.048 BindingDB Entry DOI: 10.7270/Q2VH5SBF
					More data for this Ligand-Target Pair
Protein tyrosine phosphatase type IVA 2 (Homo sapiens (Human))	BDBM50312665 (CHEMBL1088572 | Sodium 2-(2-Fluorophenyl)-6,7-meth...) Show SMILES OP([O-])(=O)OC1CC(=Nc2cc3OCOc3cc12)c1ccccc1F |c:7| Show InChI InChI=1S/C16H13FNO6P/c17-11-4-2-1-3-9(11)12-6-14(24-25(19,20)21)10-5-15-16(23-8-22-15)7-13(10)18-12/h1-5,7,14H,6,8H2,(H2,19,20,21)/p-1	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	314	n/a	n/a	n/a	n/a	n/a	n/a
China Medical University Curated by ChEMBL					Assay Description Inhibition of human PTP4A2 by enzyme assay				J Med Chem 53: 1616-26 (2010) Article DOI: 10.1021/jm901292j BindingDB Entry DOI: 10.7270/Q2XG9R8X
					More data for this Ligand-Target Pair
Protein tyrosine phosphatase type IVA 2 (Homo sapiens (Human))	BDBM50059140 (CHEMBL3393148) Show SMILES COc1cc(\C=C(/C#N)C(=O)OCC=C)cc(Br)c1O Show InChI InChI=1S/C14H12BrNO4/c1-3-4-20-14(18)10(8-16)5-9-6-11(15)13(17)12(7-9)19-2/h3,5-7,17H,1,4H2,2H3/b10-5+	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.14E+4	n/a	n/a	n/a	n/a	n/a	n/a
European Molecular Biology Laboratory Curated by ChEMBL					Assay Description Inhibition of PRL2 (unknown origin) using DiFMUP as fluorogenic phosphate substrate assessed as DiFMUP dephosphorylation				Eur J Med Chem 88: 89-100 (2014) Article DOI: 10.1016/j.ejmech.2014.08.060 BindingDB Entry DOI: 10.7270/Q2FQ9Z8G
					More data for this Ligand-Target Pair
Protein tyrosine phosphatase type IVA 2 (Homo sapiens (Human))	BDBM50059141 (CHEMBL3393149) Show SMILES COc1cc(\C=C(/C#N)C(=O)OC(C)C)cc(Br)c1O Show InChI InChI=1S/C14H14BrNO4/c1-8(2)20-14(18)10(7-16)4-9-5-11(15)13(17)12(6-9)19-3/h4-6,8,17H,1-3H3/b10-4+	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.94E+4	n/a	n/a	n/a	n/a	n/a	n/a
European Molecular Biology Laboratory Curated by ChEMBL					Assay Description Inhibition of PRL2 (unknown origin) using DiFMUP as fluorogenic phosphate substrate assessed as DiFMUP dephosphorylation				Eur J Med Chem 88: 89-100 (2014) Article DOI: 10.1016/j.ejmech.2014.08.060 BindingDB Entry DOI: 10.7270/Q2FQ9Z8G
					More data for this Ligand-Target Pair
Protein tyrosine phosphatase type IVA 2 (Homo sapiens (Human))	BDBM50059086 (CHEMBL3393146) Show SMILES Oc1ccc(\C=C(/C#N)C(=O)OCC=C)cc1Br Show InChI InChI=1S/C13H10BrNO3/c1-2-5-18-13(17)10(8-15)6-9-3-4-12(16)11(14)7-9/h2-4,6-7,16H,1,5H2/b10-6+	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.04E+5	n/a	n/a	n/a	n/a	n/a	n/a
European Molecular Biology Laboratory Curated by ChEMBL					Assay Description Inhibition of PRL2 (unknown origin) using DiFMUP as fluorogenic phosphate substrate assessed as DiFMUP dephosphorylation				Eur J Med Chem 88: 89-100 (2014) Article DOI: 10.1016/j.ejmech.2014.08.060 BindingDB Entry DOI: 10.7270/Q2FQ9Z8G
					More data for this Ligand-Target Pair
Protein tyrosine phosphatase type IVA 2 (Homo sapiens (Human))	BDBM50059084 (CHEMBL3393171 | US10308663, Thienopyridone (5)) Show SMILES Nc1c[nH]c(=O)c2cc(sc12)-c1ccccc1 Show InChI InChI=1S/C13H10N2OS/c14-10-7-15-13(16)9-6-11(17-12(9)10)8-4-2-1-3-5-8/h1-7H,14H2,(H,15,16)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.04E+5	n/a	n/a	n/a	n/a	n/a	n/a
European Molecular Biology Laboratory Curated by ChEMBL					Assay Description Inhibition of PRL2 (unknown origin) using DiFMUP as fluorogenic phosphate substrate assessed as DiFMUP dephosphorylation				Eur J Med Chem 88: 89-100 (2014) Article DOI: 10.1016/j.ejmech.2014.08.060 BindingDB Entry DOI: 10.7270/Q2FQ9Z8G
					More data for this Ligand-Target Pair
Protein tyrosine phosphatase type IVA 2 (Homo sapiens (Human))	BDBM50059142 (CHEMBL3393150) Show SMILES CCOC(=O)C(=C\c1cc(Br)c(O)c(Br)c1)\C#N Show InChI InChI=1S/C12H9Br2NO3/c1-2-18-12(17)8(6-15)3-7-4-9(13)11(16)10(14)5-7/h3-5,16H,2H2,1H3/b8-3+	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.09E+5	n/a	n/a	n/a	n/a	n/a	n/a
European Molecular Biology Laboratory Curated by ChEMBL					Assay Description Inhibition of PRL2 (unknown origin) using DiFMUP as fluorogenic phosphate substrate assessed as DiFMUP dephosphorylation				Eur J Med Chem 88: 89-100 (2014) Article DOI: 10.1016/j.ejmech.2014.08.060 BindingDB Entry DOI: 10.7270/Q2FQ9Z8G
					More data for this Ligand-Target Pair
Protein tyrosine phosphatase type IVA 2 (Homo sapiens (Human))	BDBM50059143 (CHEMBL3393151) Show SMILES CC(C)OC(=O)C(=C/c1ccc(O)c(Br)c1)\C#N Show InChI InChI=1S/C13H12BrNO3/c1-8(2)18-13(17)10(7-15)5-9-3-4-12(16)11(14)6-9/h3-6,8,16H,1-2H3/b10-5-	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
European Molecular Biology Laboratory Curated by ChEMBL					Assay Description Inhibition of PRL2 (unknown origin) using DiFMUP as fluorogenic phosphate substrate assessed as DiFMUP dephosphorylation				Eur J Med Chem 88: 89-100 (2014) Article DOI: 10.1016/j.ejmech.2014.08.060 BindingDB Entry DOI: 10.7270/Q2FQ9Z8G
					More data for this Ligand-Target Pair
Protein tyrosine phosphatase type IVA 2 (Homo sapiens (Human))	BDBM50059139 (CHEMBL3393147) Show SMILES OC(=O)c1ccc[n+]2c([O-])c(sc12)-c1ccccc1 Show InChI InChI=1S/C14H9NO3S/c16-12-11(9-5-2-1-3-6-9)19-13-10(14(17)18)7-4-8-15(12)13/h1-8H,(H-,16,17,18)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.88E+5	n/a	n/a	n/a	n/a	n/a	n/a
European Molecular Biology Laboratory Curated by ChEMBL					Assay Description Inhibition of PRL2 (unknown origin) using DiFMUP as fluorogenic phosphate substrate assessed as DiFMUP dephosphorylation				Eur J Med Chem 88: 89-100 (2014) Article DOI: 10.1016/j.ejmech.2014.08.060 BindingDB Entry DOI: 10.7270/Q2FQ9Z8G
					More data for this Ligand-Target Pair
Protein tyrosine phosphatase type IVA 2 (Homo sapiens (Human))	BDBM50059085 (CHEBI:8830 | Rhodanine) Show SMILES O=C1CSC(=S)N1 Show InChI InChI=1S/C3H3NOS2/c5-2-1-7-3(6)4-2/h1H2,(H,4,5,6)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	1.88E+5	n/a	n/a	n/a	n/a	n/a	n/a
European Molecular Biology Laboratory Curated by ChEMBL					Assay Description Inhibition of PRL2 (unknown origin) using DiFMUP as fluorogenic phosphate substrate assessed as DiFMUP dephosphorylation				Eur J Med Chem 88: 89-100 (2014) Article DOI: 10.1016/j.ejmech.2014.08.060 BindingDB Entry DOI: 10.7270/Q2FQ9Z8G
					More data for this Ligand-Target Pair