Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Ribonucleoside-diphosphate reductase large subunit/subunit M2/subunit M2 B' AND taxid = 9606   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ribonucleoside-diphosphate reductase large subunit/subunit M2/subunit M2 B (Homo sapiens (Human))	BDBM50174197 ((S)-3-(2-((3S,3aR,5S,7S,7aS)-7-((3-(9H-fluoren-9-y...) Show SMILES CC(C)CO[C@@H]1C[C@H]2[C@H](O)CN(CC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc3ccccc3)C(O)=O)[C@@H]2[C@@H](COC(=O)CCC2c3ccccc3-c3ccccc23)O1 Show InChI InChI=1S/C43H51N3O11/c1-25(2)23-56-40-19-32-35(47)21-46(22-37(48)44-33(20-38(49)50)42(52)45-34(43(53)54)18-26-10-4-3-5-11-26)41(32)36(57-40)24-55-39(51)17-16-31-29-14-8-6-12-27(29)28-13-7-9-15-30(28)31/h3-15,25,31-36,40-41,47H,16-24H2,1-2H3,(H,44,48)(H,45,52)(H,49,50)(H,53,54)/t32-,33-,34-,35+,36+,40-,41-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition of mammalian ribonucleotide reductase (mRR)				Bioorg Med Chem Lett 15: 5146-9 (2005) Article DOI: 10.1016/j.bmcl.2005.08.062 BindingDB Entry DOI: 10.7270/Q2RB745F
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