Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Ryanodine receptor 1' AND taxid = 10090   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ryanodine receptor 1 (Mus musculus)	BDBM50222771 (3-bromo-N-(4-chloro-2-methyl-6-(methylcarbamoyl)ph...) Show SMILES CNC(=O)c1cc(Cl)cc(C)c1NC(=O)c1cc(Br)nn1-c1ncccc1Cl Show InChI InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a
DuPont Crop Protection Curated by ChEMBL					Assay Description Activation of ryanodine receptor 1 in mouse C2C12 cells assessed as induction of calcium mobilization				Bioorg Med Chem 17: 4127-33 (2009) Article DOI: 10.1016/j.bmc.2009.01.018 BindingDB Entry DOI: 10.7270/Q2BG2P11
					More data for this Ligand-Target Pair				3D Structure (crystal)