Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
AP-2 complex subunit sigma (RAT) | BDBM21398 (4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 24.2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Washington University School of Medicine Curated by ChEMBL | Assay Description Displacement of [3H]-DTG from rat sigma2 receptor by liquid scintillation counting | J Med Chem 54: 1555-64 (2011) Article DOI: 10.1021/jm101323b BindingDB Entry DOI: 10.7270/Q2WD40W0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
AP-2 complex subunit sigma (RAT) | BDBM50339687 (4-(Dimethylamino)-N-(4-(4-(2-(2-fluoroethoxy)pheny...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 650 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Washington University School of Medicine Curated by ChEMBL | Assay Description Displacement of [3H]-DTG from rat sigma2 receptor by liquid scintillation counting | J Med Chem 54: 1555-64 (2011) Article DOI: 10.1021/jm101323b BindingDB Entry DOI: 10.7270/Q2WD40W0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
AP-2 complex subunit sigma (RAT) | BDBM50339689 (4-(2-Fluoroethoxy)-N-(4-(4-(2-methoxyphenyl)-piper...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 660 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Washington University School of Medicine Curated by ChEMBL | Assay Description Displacement of [3H]-DTG from rat sigma2 receptor by liquid scintillation counting | J Med Chem 54: 1555-64 (2011) Article DOI: 10.1021/jm101323b BindingDB Entry DOI: 10.7270/Q2WD40W0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
AP-2 complex subunit sigma (RAT) | BDBM50339686 (4-(2-Fluoroethoxy)-N-(4-(4-(2-(2-fluoroethoxy)phen...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 794 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Washington University School of Medicine Curated by ChEMBL | Assay Description Displacement of [3H]-DTG from rat sigma2 receptor by liquid scintillation counting | J Med Chem 54: 1555-64 (2011) Article DOI: 10.1021/jm101323b BindingDB Entry DOI: 10.7270/Q2WD40W0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
AP-2 complex subunit sigma (RAT) | BDBM50339688 (4-(2-(2-(2-Fluoroethoxy)ethoxy)ethoxy)-N-(4-(4-(2-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.12E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Washington University School of Medicine Curated by ChEMBL | Assay Description Displacement of [3H]-DTG from rat sigma2 receptor by liquid scintillation counting | J Med Chem 54: 1555-64 (2011) Article DOI: 10.1021/jm101323b BindingDB Entry DOI: 10.7270/Q2WD40W0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
AP-2 complex subunit sigma (RAT) | BDBM50339683 (4-(Thiophen-3-yl)-N-(4-(4-(2-(2-fluoroethoxy)pheny...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.32E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Washington University School of Medicine Curated by ChEMBL | Assay Description Displacement of [3H]-DTG from rat sigma2 receptor by liquid scintillation counting | J Med Chem 54: 1555-64 (2011) Article DOI: 10.1021/jm101323b BindingDB Entry DOI: 10.7270/Q2WD40W0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
AP-2 complex subunit sigma (RAT) | BDBM50339691 (4-(dimethylamino)-N-(4-(4-(2-methoxyphenyl)piperaz...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.57E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Washington University School of Medicine Curated by ChEMBL | Assay Description Displacement of [3H]-DTG from rat sigma2 receptor by liquid scintillation counting | J Med Chem 54: 1555-64 (2011) Article DOI: 10.1021/jm101323b BindingDB Entry DOI: 10.7270/Q2WD40W0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
AP-2 complex subunit sigma (RAT) | BDBM50339684 (4-(2-Fluoroethyl)-N-(4-(4-(2-(2-Fluoroethoxy)pheny...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.02E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Washington University School of Medicine Curated by ChEMBL | Assay Description Displacement of [3H]-DTG from rat sigma2 receptor by liquid scintillation counting | J Med Chem 54: 1555-64 (2011) Article DOI: 10.1021/jm101323b BindingDB Entry DOI: 10.7270/Q2WD40W0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
AP-2 complex subunit sigma (RAT) | BDBM50339690 (4-(2-fluoroethyl)-N-(4-(4-(2-methoxyphenyl)piperaz...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.21E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Washington University School of Medicine Curated by ChEMBL | Assay Description Displacement of [3H]-DTG from rat sigma2 receptor by liquid scintillation counting | J Med Chem 54: 1555-64 (2011) Article DOI: 10.1021/jm101323b BindingDB Entry DOI: 10.7270/Q2WD40W0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
AP-2 complex subunit sigma (RAT) | BDBM50339685 (4-(Thiophen-3-yl)-N-(4-(4-(2-(2-fluoroethoxy)pheny...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.96E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Washington University School of Medicine Curated by ChEMBL | Assay Description Displacement of [3H]-DTG from rat sigma2 receptor by liquid scintillation counting | J Med Chem 54: 1555-64 (2011) Article DOI: 10.1021/jm101323b BindingDB Entry DOI: 10.7270/Q2WD40W0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
AP-2 complex subunit sigma (RAT) | BDBM26739 (3-(3-carbamoylphenyl)phenyl N-cyclohexylcarbamate ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
McGill University Curated by PDSP Ki Database | Proc Natl Acad Sci U S A 102: 18620-5 (2005) Article DOI: 10.1073/pnas.0509591102 BindingDB Entry DOI: 10.7270/Q2F47MQJ | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
AP-2 complex subunit sigma (RAT) | BDBM81790 (Amisulpride | CAS_71675-85-9 | NSC_2159 | US101672...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase DrugBank MCE PC cid PC sid UniChem Patents Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Case Western Reserve University Curated by PDSP Ki Database | Psychopharmacology (Berl) 205: 119-28 (2009) Article DOI: 10.1007/s00213-009-1521-8 BindingDB Entry DOI: 10.7270/Q2TB15G7 | ||||||||||||
More data for this Ligand-Target Pair |