Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase Sgk1' AND taxid = 10090   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Sgk1 (Mus musculus (Mouse))	BDBM213821 (US9296775, 1) Show SMILES CC(C)c1[nH]nc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c1Cc1ccc(\C=C\CCN2CCCC3(CCNCC3)C2)cc1C |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	7.5	37
ELI LILLY AND COMPANY US Patent					Assay Description The SGLT activity is measured as sodium-dependent 14C-AMG uptake in the above cell lines described as follows. One hundred uL of culture medium conta...				US Patent US9296775 (2016) BindingDB Entry DOI: 10.7270/Q2CZ3609
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Sgk1 (Mus musculus (Mouse))	BDBM268921 (US9718825, Example 346) Show SMILES CC(C)N1CCC(CC1)Oc1nc(nc2[nH]nc(C)c12)-c1ccc(NS(=O)(=O)c2cc(Cl)ccc2F)cc1 Show InChI InChI=1S/C26H28ClFN6O3S/c1-15(2)34-12-10-20(11-13-34)37-26-23-16(3)31-32-25(23)29-24(30-26)17-4-7-19(8-5-17)33-38(35,36)22-14-18(27)6-9-21(22)28/h4-9,14-15,20,33H,10-13H2,1-3H3,(H,29,30,31,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	171	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of mouse SGK1 in presence 500 uM presence of ATP				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01601 BindingDB Entry DOI: 10.7270/Q2P55SCW
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Sgk1 (Mus musculus (Mouse))	BDBM50043019 (CHEMBL3355029) Show SMILES O[C@H]1CC[C@@H](CC1)Oc1nc(nc2[nH]ncc12)-c1ccc(NS(=O)(=O)c2cc(Cl)ccc2F)cc1 |r,wU:4.7,wD:1.0,(43,-11.27,;41.45,-11.27,;40.68,-9.93,;39.13,-9.93,;38.37,-11.26,;39.14,-12.6,;40.68,-12.61,;36.83,-11.26,;36.06,-12.6,;34.52,-12.6,;33.75,-13.93,;34.52,-15.27,;36.05,-15.27,;37.07,-16.42,;38.48,-15.8,;38.34,-14.27,;36.83,-13.94,;32.21,-13.93,;31.43,-15.26,;29.89,-15.26,;29.13,-13.92,;27.59,-13.91,;26.81,-15.24,;28.15,-16.01,;26.81,-16.78,;25.27,-15.25,;24.5,-13.91,;22.96,-13.92,;22.18,-12.58,;22.2,-15.25,;22.96,-16.57,;24.5,-16.58,;25.27,-17.91,;29.9,-12.59,;31.44,-12.59,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	253	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of mouse SGK1 in presence 500 uM presence of ATP				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01601 BindingDB Entry DOI: 10.7270/Q2P55SCW
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Sgk1 (Mus musculus (Mouse))	BDBM269003 (N-[4-(3-Amino-1H-pyrazolo[3,4-d]pyrimidin-6-yl)-ph...) Show SMILES Nc1n[nH]c2nc(ncc12)-c1ccc(NS(=O)(=O)c2cc(Cl)ccc2C#N)cc1 Show InChI InChI=1S/C18H12ClN7O2S/c19-12-4-1-11(8-20)15(7-12)29(27,28)26-13-5-2-10(3-6-13)17-22-9-14-16(21)24-25-18(14)23-17/h1-7,9,26H,(H3,21,22,23,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	294	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of mouse SGK1 in presence 500 uM presence of ATP				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01601 BindingDB Entry DOI: 10.7270/Q2P55SCW
					More data for this Ligand-Target Pair