Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Sphingosine-1-phosphate lyase 1' AND taxid = 10090   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sphingosine-1-phosphate lyase 1 (Mus musculus)	BDBM50268100 (CHEMBL491458 | N-(4-(1H-imidazol-1-yl)benzyl)-4-am...) Show SMILES Nc1nc(nc2n(CC3CCCO3)cc(C(=O)NCc3ccc(cc3)-n3ccnc3)c(=O)c12)N1CCCCC1 Show InChI InChI=1S/C28H32N8O3/c29-25-23-24(37)22(27(38)31-15-19-6-8-20(9-7-19)35-13-10-30-18-35)17-36(16-21-5-4-14-39-21)26(23)33-28(32-25)34-11-2-1-3-12-34/h6-10,13,17-18,21H,1-5,11-12,14-16H2,(H,31,38)(H2,29,32,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibition of sphingosine-1-phosphate lyase in mouse spleen by scintillation counting				J Med Chem 52: 3941-53 (2009) Article DOI: 10.1021/jm900278w BindingDB Entry DOI: 10.7270/Q2QZ29WX
					More data for this Ligand-Target Pair
Sphingosine-1-phosphate lyase 1 (Mus musculus)	BDBM50158336 (2-(4-octylphenethyl)-2-aminopropane-1,3-diol | 2-A...) Show SMILES CCCCCCCCc1ccc(CCC(N)(CO)CO)cc1 Show InChI InChI=1S/C19H33NO2/c1-2-3-4-5-6-7-8-17-9-11-18(12-10-17)13-14-19(20,15-21)16-22/h9-12,21-22H,2-8,13-16,20H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.24E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of mouse liver microsomal S1PL using S1P as substrate incubated for 20 mins by ESI-LC/MS analysis				Citation and Details Article DOI: 10.1016/j.ejmech.2016.08.008 BindingDB Entry DOI: 10.7270/Q29W0K5N
					More data for this Ligand-Target Pair