Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sphingosine 1-phosphate receptor 1 (Canis lupus familiaris) | BDBM50041691 (CHEMBL3358920 | US11149292, Compound (R)-2-(7-(4-c...) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.340 | n/a | n/a | n/a | n/a |
Arena Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Agonist activity at dog S1P1 receptor assessed as cAMP accumulation by HTRF assay | ACS Med Chem Lett 5: 1313-7 (2014) Article DOI: 10.1021/ml500389m BindingDB Entry DOI: 10.7270/Q29W0H4C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine 1-phosphate receptor 1 (Canis lupus familiaris) | BDBM50063864 (CHEMBL3403619 | US10676467, Compound TZ 50 13) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.0400 | n/a | n/a | n/a | n/a |
Arena Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Agonist activity at dog S1P1 receptor assessed as change in cAMP level by homogeneous time resolved fluorescence cyclase assay | Bioorg Med Chem Lett 25: 659-63 (2015) Article DOI: 10.1016/j.bmcl.2014.11.089 BindingDB Entry DOI: 10.7270/Q25T3N5P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine 1-phosphate receptor 1 (Canis lupus familiaris) | BDBM50041983 (CHEMBL3359523) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.0490 | n/a | n/a | n/a | n/a |
Arena Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Agonist activity at dog S1P1 receptor assessed as cAMP accumulation by HTRF assay | ACS Med Chem Lett 5: 1334-9 (2014) Article DOI: 10.1021/ml500422m BindingDB Entry DOI: 10.7270/Q2XK8H6S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine 1-phosphate receptor 1 (Canis lupus familiaris) | BDBM50041982 (CHEMBL3359522) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.0490 | n/a | n/a | n/a | n/a |
Arena Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Agonist activity at dog S1P1 receptor assessed as cAMP accumulation by HTRF assay | ACS Med Chem Lett 5: 1334-9 (2014) Article DOI: 10.1021/ml500422m BindingDB Entry DOI: 10.7270/Q2XK8H6S | |||||||||||
More data for this Ligand-Target Pair |