Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Angiopoietin-1 receptor (Homo sapiens (Human)) | BDBM50421257 (CHEMBL2087875) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc. Curated by ChEMBL | Assay Description Inhibition of TIE2 | Bioorg Med Chem Lett 22: 6212-7 (2012) Article DOI: 10.1016/j.bmcl.2012.08.020 BindingDB Entry DOI: 10.7270/Q2VH5Q4X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiopoietin-1 receptor (Homo sapiens (Human)) | BDBM50355491 (CHEMBL1835870) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kentucky Curated by ChEMBL | Assay Description Inhibition of Tie2 | J Med Chem 55: 725-34 (2012) Article DOI: 10.1021/jm201198w BindingDB Entry DOI: 10.7270/Q2GQ6Z6R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiopoietin-1 receptor (Homo sapiens (Human)) | BDBM50341519 ((S)-3-(4-(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals (Europe) Ltd. Curated by ChEMBL | Assay Description Inhibition of TIE2 | J Med Chem 54: 2341-50 (2011) Article DOI: 10.1021/jm101499u BindingDB Entry DOI: 10.7270/Q2KH0NPW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiopoietin-1 receptor (Homo sapiens (Human)) | BDBM50245852 (CHEMBL458333 | N3-(2,6-dimethylphenyl)-1-(3-methox...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc. Curated by ChEMBL | Assay Description Inhibition of Tie2 (unknown origin) | Bioorg Med Chem Lett 18: 6352-6 (2008) Article DOI: 10.1016/j.bmcl.2008.10.092 BindingDB Entry DOI: 10.7270/Q2B56JKZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiopoietin-1 receptor (Homo sapiens (Human)) | BDBM50463483 (CHEMBL4245242) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | Article PubMed | >2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc Curated by ChEMBL | Assay Description Inhibition of TIE2 (unknown origin) | Bioorg Med Chem Lett 28: 2622-2626 (2018) Article DOI: 10.1016/j.bmcl.2018.06.040 BindingDB Entry DOI: 10.7270/Q2ZC85HX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiopoietin-1 receptor (Homo sapiens (Human)) | BDBM50463484 (CHEMBL4248525) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | Article PubMed | >2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc Curated by ChEMBL | Assay Description Inhibition of TIE2 (unknown origin) | Bioorg Med Chem Lett 28: 2622-2626 (2018) Article DOI: 10.1016/j.bmcl.2018.06.040 BindingDB Entry DOI: 10.7270/Q2ZC85HX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiopoietin-1 receptor (Homo sapiens (Human)) | BDBM50463479 (CHEMBL4249925) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | Article PubMed | >2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc Curated by ChEMBL | Assay Description Inhibition of TIE2 (unknown origin) | Bioorg Med Chem Lett 28: 2622-2626 (2018) Article DOI: 10.1016/j.bmcl.2018.06.040 BindingDB Entry DOI: 10.7270/Q2ZC85HX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiopoietin-1 receptor (Homo sapiens (Human)) | BDBM50245853 (CHEMBL502156 | N3-(2,6-dimethylphenyl)-N6-(3-fluor...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc. Curated by ChEMBL | Assay Description Inhibition of Tie2 (unknown origin) | Bioorg Med Chem Lett 18: 6352-6 (2008) Article DOI: 10.1016/j.bmcl.2008.10.092 BindingDB Entry DOI: 10.7270/Q2B56JKZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiopoietin-1 receptor (Homo sapiens (Human)) | BDBM50237710 (4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifl...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 3.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Genomics Institute of the Novartis Research Foundation Curated by PDSP Ki Database | Proc Natl Acad Sci U S A 103: 3153-8 (2006) Article DOI: 10.1073/pnas.0511292103 BindingDB Entry DOI: 10.7270/Q21Z430B | ||||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Angiopoietin-1 receptor (Homo sapiens (Human)) | BDBM50245904 (CHEMBL459044 | N-(2,6-dimethylphenyl)-4-(2-ethoxyp...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | >8.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc. Curated by ChEMBL | Assay Description Inhibition of Tie2 (unknown origin) | Bioorg Med Chem Lett 18: 6352-6 (2008) Article DOI: 10.1016/j.bmcl.2008.10.092 BindingDB Entry DOI: 10.7270/Q2B56JKZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiopoietin-1 receptor (Homo sapiens (Human)) | BDBM13530 (4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Genomics Institute of the Novartis Research Foundation Curated by PDSP Ki Database | Proc Natl Acad Sci U S A 103: 3153-8 (2006) Article DOI: 10.1073/pnas.0511292103 BindingDB Entry DOI: 10.7270/Q21Z430B | ||||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Angiopoietin-1 receptor (Homo sapiens (Human)) | BDBM50297455 (1-((6-fluoro-4H-benzo[d][1,3]dioxin-8-yl)methyl)-3...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc Curated by ChEMBL | Assay Description Inhibition of Tie2 | Bioorg Med Chem Lett 19: 2891-5 (2009) Article DOI: 10.1016/j.bmcl.2009.03.043 BindingDB Entry DOI: 10.7270/Q2F76CMZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiopoietin-1 receptor (Homo sapiens (Human)) | BDBM50395892 (CHEMBL2163772) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Martin-Luther University Halle-Wittenberg Curated by ChEMBL | Assay Description Inhibition of TIE2 | Bioorg Med Chem Lett 22: 6914-8 (2012) Article DOI: 10.1016/j.bmcl.2012.09.006 BindingDB Entry DOI: 10.7270/Q2M61MC1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiopoietin-1 receptor (Homo sapiens (Human)) | BDBM50331612 (CHEMBL1290072 | N-(4-methoxybenzyl)benzofuro[2,3-b...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Martin Luther University Halle-Wittenberg Curated by ChEMBL | Assay Description Inhibition of human TIE2 | Bioorg Med Chem Lett 20: 6915-9 (2010) Article DOI: 10.1016/j.bmcl.2010.10.004 BindingDB Entry DOI: 10.7270/Q2GF0TQS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiopoietin-1 receptor (Homo sapiens (Human)) | BDBM50230178 (CHEMBL4087541) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.130 | n/a | n/a | n/a | n/a | n/a | n/a |
Xi'an Jiaotong University Curated by ChEMBL | Assay Description Inhibition of TIE-2 (unknown origin) after 60 mins by ADP-Glo assay | Eur J Med Chem 127: 275-285 (2017) Article DOI: 10.1016/j.ejmech.2016.12.059 BindingDB Entry DOI: 10.7270/Q2XW4N27 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiopoietin-1 receptor (Homo sapiens (Human)) | BDBM50230179 (CHEMBL4103584) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.160 | n/a | n/a | n/a | n/a | n/a | n/a |
Xi'an Jiaotong University Curated by ChEMBL | Assay Description Inhibition of TIE-2 (unknown origin) after 60 mins by ADP-Glo assay | Eur J Med Chem 127: 275-285 (2017) Article DOI: 10.1016/j.ejmech.2016.12.059 BindingDB Entry DOI: 10.7270/Q2XW4N27 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiopoietin-1 receptor [776-1124] (Homo sapiens (Human)) | BDBM239621 (US9394309, 147 | US9394309, 74) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | US Patent | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Bayer Pharma Aktiengesellschaft; Bayer Intellectual Property GmbH US Patent | Assay Description For the assay, 50 nl of a 100-fold concentrated solution of the respective test substance in DMSO were pipetted into a black low-volume 384-well micr... | US Patent US9394309 (2016) BindingDB Entry DOI: 10.7270/Q2C53JRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiopoietin-1 receptor (Homo sapiens (Human)) | BDBM50507550 (CHEMBL4449700) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.260 | n/a | n/a | n/a | n/a | n/a | n/a |
Xi'an Jiaotong University Curated by ChEMBL | Assay Description Inhibition of TIE2 (unknown origin) after 4 hrs by ADP-Glo reagent based luminescent assay | Eur J Med Chem 163: 1-9 (2019) Article DOI: 10.1016/j.ejmech.2018.11.042 BindingDB Entry DOI: 10.7270/Q2XS5ZPC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiopoietin-1 receptor (Homo sapiens (Human)) | BDBM50507542 (CHEMBL4447552) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.280 | n/a | n/a | n/a | n/a | n/a | n/a |
Xi'an Jiaotong University Curated by ChEMBL | Assay Description Inhibition of TIE2 (unknown origin) after 4 hrs by ADP-Glo reagent based luminescent assay | Eur J Med Chem 163: 1-9 (2019) Article DOI: 10.1016/j.ejmech.2018.11.042 BindingDB Entry DOI: 10.7270/Q2XS5ZPC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiopoietin-1 receptor [776-1124] (Homo sapiens (Human)) | BDBM239564 (US9394309, 17) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Bayer Pharma Aktiengesellschaft; Bayer Intellectual Property GmbH US Patent | Assay Description For the assay, 50 nl of a 100-fold concentrated solution of the respective test substance in DMSO were pipetted into a black low-volume 384-well micr... | US Patent US9394309 (2016) BindingDB Entry DOI: 10.7270/Q2C53JRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiopoietin-1 receptor [776-1124] (Homo sapiens (Human)) | BDBM239570 (US9394309, 23) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Bayer Pharma Aktiengesellschaft; Bayer Intellectual Property GmbH US Patent | Assay Description For the assay, 50 nl of a 100-fold concentrated solution of the respective test substance in DMSO were pipetted into a black low-volume 384-well micr... | US Patent US9394309 (2016) BindingDB Entry DOI: 10.7270/Q2C53JRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiopoietin-1 receptor (Homo sapiens (Human)) | BDBM50507536 (CHEMBL4528844) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a |
Xi'an Jiaotong University Curated by ChEMBL | Assay Description Inhibition of TIE2 (unknown origin) after 4 hrs by ADP-Glo reagent based luminescent assay | Eur J Med Chem 163: 1-9 (2019) Article DOI: 10.1016/j.ejmech.2018.11.042 BindingDB Entry DOI: 10.7270/Q2XS5ZPC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiopoietin-1 receptor [776-1124] (Homo sapiens (Human)) | BDBM239708 (US9394309, 166) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Bayer Pharma Aktiengesellschaft; Bayer Intellectual Property GmbH US Patent | Assay Description For the assay, 50 nl of a 100-fold concentrated solution of the respective test substance in DMSO were pipetted into a black low-volume 384-well micr... | US Patent US9394309 (2016) BindingDB Entry DOI: 10.7270/Q2C53JRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiopoietin-1 receptor [776-1124] (Homo sapiens (Human)) | BDBM239712 (US9394309, 171) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Bayer Pharma Aktiengesellschaft; Bayer Intellectual Property GmbH US Patent | Assay Description For the assay, 50 nl of a 100-fold concentrated solution of the respective test substance in DMSO were pipetted into a black low-volume 384-well micr... | US Patent US9394309 (2016) BindingDB Entry DOI: 10.7270/Q2C53JRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiopoietin-1 receptor [776-1124] (Homo sapiens (Human)) | BDBM239658 (US9394309, 114) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Bayer Pharma Aktiengesellschaft; Bayer Intellectual Property GmbH US Patent | Assay Description For the assay, 50 nl of a 100-fold concentrated solution of the respective test substance in DMSO were pipetted into a black low-volume 384-well micr... | US Patent US9394309 (2016) BindingDB Entry DOI: 10.7270/Q2C53JRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiopoietin-1 receptor [776-1124] (Homo sapiens (Human)) | BDBM239696 (US9394309, 153) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Bayer Pharma Aktiengesellschaft; Bayer Intellectual Property GmbH US Patent | Assay Description For the assay, 50 nl of a 100-fold concentrated solution of the respective test substance in DMSO were pipetted into a black low-volume 384-well micr... | US Patent US9394309 (2016) BindingDB Entry DOI: 10.7270/Q2C53JRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiopoietin-1 receptor [776-1124] (Homo sapiens (Human)) | BDBM239583 (US9394309, 36) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Bayer Pharma Aktiengesellschaft; Bayer Intellectual Property GmbH US Patent | Assay Description For the assay, 50 nl of a 100-fold concentrated solution of the respective test substance in DMSO were pipetted into a black low-volume 384-well micr... | US Patent US9394309 (2016) BindingDB Entry DOI: 10.7270/Q2C53JRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiopoietin-1 receptor [776-1124] (Homo sapiens (Human)) | BDBM239594 (US9394309, 47) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Bayer Pharma Aktiengesellschaft; Bayer Intellectual Property GmbH US Patent | Assay Description For the assay, 50 nl of a 100-fold concentrated solution of the respective test substance in DMSO were pipetted into a black low-volume 384-well micr... | US Patent US9394309 (2016) BindingDB Entry DOI: 10.7270/Q2C53JRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiopoietin-1 receptor [776-1124] (Homo sapiens (Human)) | BDBM239595 (US9394309, 48) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Bayer Pharma Aktiengesellschaft; Bayer Intellectual Property GmbH US Patent | Assay Description For the assay, 50 nl of a 100-fold concentrated solution of the respective test substance in DMSO were pipetted into a black low-volume 384-well micr... | US Patent US9394309 (2016) BindingDB Entry DOI: 10.7270/Q2C53JRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiopoietin-1 receptor [776-1124] (Homo sapiens (Human)) | BDBM239596 (US9394309, 49) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Bayer Pharma Aktiengesellschaft; Bayer Intellectual Property GmbH US Patent | Assay Description For the assay, 50 nl of a 100-fold concentrated solution of the respective test substance in DMSO were pipetted into a black low-volume 384-well micr... | US Patent US9394309 (2016) BindingDB Entry DOI: 10.7270/Q2C53JRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiopoietin-1 receptor [776-1124] (Homo sapiens (Human)) | BDBM239620 (US9394309, 73) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Bayer Pharma Aktiengesellschaft; Bayer Intellectual Property GmbH US Patent | Assay Description For the assay, 50 nl of a 100-fold concentrated solution of the respective test substance in DMSO were pipetted into a black low-volume 384-well micr... | US Patent US9394309 (2016) BindingDB Entry DOI: 10.7270/Q2C53JRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiopoietin-1 receptor [776-1124] (Homo sapiens (Human)) | BDBM239548 (US9394309, 1) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Bayer Pharma Aktiengesellschaft; Bayer Intellectual Property GmbH US Patent | Assay Description For the assay, 50 nl of a 100-fold concentrated solution of the respective test substance in DMSO were pipetted into a black low-volume 384-well micr... | US Patent US9394309 (2016) BindingDB Entry DOI: 10.7270/Q2C53JRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiopoietin-1 receptor [776-1124] (Homo sapiens (Human)) | BDBM239557 (US9394309, 10) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Bayer Pharma Aktiengesellschaft; Bayer Intellectual Property GmbH US Patent | Assay Description For the assay, 50 nl of a 100-fold concentrated solution of the respective test substance in DMSO were pipetted into a black low-volume 384-well micr... | US Patent US9394309 (2016) BindingDB Entry DOI: 10.7270/Q2C53JRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiopoietin-1 receptor [776-1124] (Homo sapiens (Human)) | BDBM239558 (US9394309, 11) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Bayer Pharma Aktiengesellschaft; Bayer Intellectual Property GmbH US Patent | Assay Description For the assay, 50 nl of a 100-fold concentrated solution of the respective test substance in DMSO were pipetted into a black low-volume 384-well micr... | US Patent US9394309 (2016) BindingDB Entry DOI: 10.7270/Q2C53JRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiopoietin-1 receptor (Homo sapiens (Human)) | BDBM50507538 (CHEMBL4452256) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.360 | n/a | n/a | n/a | n/a | n/a | n/a |
Xi'an Jiaotong University Curated by ChEMBL | Assay Description Inhibition of TIE2 (unknown origin) after 4 hrs by ADP-Glo reagent based luminescent assay | Eur J Med Chem 163: 1-9 (2019) Article DOI: 10.1016/j.ejmech.2018.11.042 BindingDB Entry DOI: 10.7270/Q2XS5ZPC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiopoietin-1 receptor (Homo sapiens (Human)) | BDBM16673 (4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 0.390 | n/a | n/a | n/a | n/a | n/a | n/a |
The First Affiliated Hospital of Xi'an Jiaotong University Curated by ChEMBL | Assay Description Inhibition of Tie-2 (unknown origin) after 1 hrs by ADP-Glo luminescence assay | Eur J Med Chem 164: 440-447 (2019) Article DOI: 10.1016/j.ejmech.2018.12.067 BindingDB Entry DOI: 10.7270/Q2B27ZRH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiopoietin-1 receptor (Homo sapiens (Human)) | BDBM16673 (4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 0.390 | n/a | n/a | n/a | n/a | n/a | n/a |
Xi'an Jiaotong University Curated by ChEMBL | Assay Description Inhibition of TIE2 (unknown origin) after 4 hrs by ADP-Glo reagent based luminescent assay | Eur J Med Chem 163: 1-9 (2019) Article DOI: 10.1016/j.ejmech.2018.11.042 BindingDB Entry DOI: 10.7270/Q2XS5ZPC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiopoietin-1 receptor [776-1124] (Homo sapiens (Human)) | BDBM239697 (US9394309, 154) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Bayer Pharma Aktiengesellschaft; Bayer Intellectual Property GmbH US Patent | Assay Description For the assay, 50 nl of a 100-fold concentrated solution of the respective test substance in DMSO were pipetted into a black low-volume 384-well micr... | US Patent US9394309 (2016) BindingDB Entry DOI: 10.7270/Q2C53JRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiopoietin-1 receptor [776-1124] (Homo sapiens (Human)) | BDBM239579 (US9394309, 32) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Bayer Pharma Aktiengesellschaft; Bayer Intellectual Property GmbH US Patent | Assay Description For the assay, 50 nl of a 100-fold concentrated solution of the respective test substance in DMSO were pipetted into a black low-volume 384-well micr... | US Patent US9394309 (2016) BindingDB Entry DOI: 10.7270/Q2C53JRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiopoietin-1 receptor [776-1124] (Homo sapiens (Human)) | BDBM239584 (US9394309, 37) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Bayer Pharma Aktiengesellschaft; Bayer Intellectual Property GmbH US Patent | Assay Description For the assay, 50 nl of a 100-fold concentrated solution of the respective test substance in DMSO were pipetted into a black low-volume 384-well micr... | US Patent US9394309 (2016) BindingDB Entry DOI: 10.7270/Q2C53JRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiopoietin-1 receptor [776-1124] (Homo sapiens (Human)) | BDBM239695 (US9394309, 152) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Bayer Pharma Aktiengesellschaft; Bayer Intellectual Property GmbH US Patent | Assay Description For the assay, 50 nl of a 100-fold concentrated solution of the respective test substance in DMSO were pipetted into a black low-volume 384-well micr... | US Patent US9394309 (2016) BindingDB Entry DOI: 10.7270/Q2C53JRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiopoietin-1 receptor [776-1124] (Homo sapiens (Human)) | BDBM239691 (US9394309, 148) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Bayer Pharma Aktiengesellschaft; Bayer Intellectual Property GmbH US Patent | Assay Description For the assay, 50 nl of a 100-fold concentrated solution of the respective test substance in DMSO were pipetted into a black low-volume 384-well micr... | US Patent US9394309 (2016) BindingDB Entry DOI: 10.7270/Q2C53JRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiopoietin-1 receptor [776-1124] (Homo sapiens (Human)) | BDBM239561 (US9394309, 14) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Bayer Pharma Aktiengesellschaft; Bayer Intellectual Property GmbH US Patent | Assay Description For the assay, 50 nl of a 100-fold concentrated solution of the respective test substance in DMSO were pipetted into a black low-volume 384-well micr... | US Patent US9394309 (2016) BindingDB Entry DOI: 10.7270/Q2C53JRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiopoietin-1 receptor [776-1124] (Homo sapiens (Human)) | BDBM239706 (US9394309, 164) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Bayer Pharma Aktiengesellschaft; Bayer Intellectual Property GmbH US Patent | Assay Description For the assay, 50 nl of a 100-fold concentrated solution of the respective test substance in DMSO were pipetted into a black low-volume 384-well micr... | US Patent US9394309 (2016) BindingDB Entry DOI: 10.7270/Q2C53JRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiopoietin-1 receptor [776-1124] (Homo sapiens (Human)) | BDBM239661 (US9394309, 118) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Bayer Pharma Aktiengesellschaft; Bayer Intellectual Property GmbH US Patent | Assay Description For the assay, 50 nl of a 100-fold concentrated solution of the respective test substance in DMSO were pipetted into a black low-volume 384-well micr... | US Patent US9394309 (2016) BindingDB Entry DOI: 10.7270/Q2C53JRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiopoietin-1 receptor (Homo sapiens (Human)) | BDBM50507535 (CHEMBL4570075) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.450 | n/a | n/a | n/a | n/a | n/a | n/a |
Xi'an Jiaotong University Curated by ChEMBL | Assay Description Inhibition of TIE2 (unknown origin) after 4 hrs by ADP-Glo reagent based luminescent assay | Eur J Med Chem 163: 1-9 (2019) Article DOI: 10.1016/j.ejmech.2018.11.042 BindingDB Entry DOI: 10.7270/Q2XS5ZPC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiopoietin-1 receptor [776-1124] (Homo sapiens (Human)) | BDBM239683 (US9394309, 140) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Bayer Pharma Aktiengesellschaft; Bayer Intellectual Property GmbH US Patent | Assay Description For the assay, 50 nl of a 100-fold concentrated solution of the respective test substance in DMSO were pipetted into a black low-volume 384-well micr... | US Patent US9394309 (2016) BindingDB Entry DOI: 10.7270/Q2C53JRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiopoietin-1 receptor [776-1124] (Homo sapiens (Human)) | BDBM239622 (US9394309, 75) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Bayer Pharma Aktiengesellschaft; Bayer Intellectual Property GmbH US Patent | Assay Description For the assay, 50 nl of a 100-fold concentrated solution of the respective test substance in DMSO were pipetted into a black low-volume 384-well micr... | US Patent US9394309 (2016) BindingDB Entry DOI: 10.7270/Q2C53JRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiopoietin-1 receptor [776-1124] (Homo sapiens (Human)) | BDBM239700 (US9394309, 157) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Bayer Pharma Aktiengesellschaft; Bayer Intellectual Property GmbH US Patent | Assay Description For the assay, 50 nl of a 100-fold concentrated solution of the respective test substance in DMSO were pipetted into a black low-volume 384-well micr... | US Patent US9394309 (2016) BindingDB Entry DOI: 10.7270/Q2C53JRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiopoietin-1 receptor [776-1124] (Homo sapiens (Human)) | BDBM239621 (US9394309, 147 | US9394309, 74) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | US Patent | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Bayer Pharma Aktiengesellschaft; Bayer Intellectual Property GmbH US Patent | Assay Description For the assay, 50 nl of a 100-fold concentrated solution of the respective test substance in DMSO were pipetted into a black low-volume 384-well micr... | US Patent US9394309 (2016) BindingDB Entry DOI: 10.7270/Q2C53JRC | |||||||||||
More data for this Ligand-Target Pair |
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