Compile Data Set for Download or QSAR

Found 210 hits Enz. Inhib. hit(s) with Target = 'Trace amine-associated receptor 7b' AND taxid = 10116   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Trace amine-associated receptor 7b (Rattus norvegicus (Rat))	BDBM129529 (US8802673, 171) Show SMILES Clc1cc(ccc1Nc1ncc(cn1)C1CC1)[C@H]1CNCCO1 |r| Show InChI InChI=1S/C17H19ClN4O/c18-14-7-12(16-10-19-5-6-23-16)3-4-15(14)22-17-20-8-13(9-21-17)11-1-2-11/h3-4,7-9,11,16,19H,1-2,5-6,10H2,(H,20,21,22)/t16-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.10	-53.2	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US8802673 (2014) BindingDB Entry DOI: 10.7270/Q2348J2G
					More data for this Ligand-Target Pair
Trace amine-associated receptor 7b (Rattus norvegicus (Rat))	BDBM129552 (US8802673, 194) Show SMILES Clc1cc(Nc2ncc(cn2)C2CC2)ccc1[C@@H]1CNCCO1 |r| Show InChI InChI=1S/C17H19ClN4O/c18-15-7-13(3-4-14(15)16-10-19-5-6-23-16)22-17-20-8-12(9-21-17)11-1-2-11/h3-4,7-9,11,16,19H,1-2,5-6,10H2,(H,20,21,22)/t16-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.10	-53.2	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US8802673 (2014) BindingDB Entry DOI: 10.7270/Q2348J2G
					More data for this Ligand-Target Pair
Trace amine-associated receptor 7b (Rattus norvegicus (Rat))	BDBM129569 (US8802673, 211) Show SMILES FC(F)(F)COc1ccnc(Nc2ccc(C3CNCCO3)c(Cl)c2)n1 Show InChI InChI=1S/C16H16ClF3N4O2/c17-12-7-10(1-2-11(12)13-8-21-5-6-25-13)23-15-22-4-3-14(24-15)26-9-16(18,19)20/h1-4,7,13,21H,5-6,8-9H2,(H,22,23,24)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.10	-53.2	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US8802673 (2014) BindingDB Entry DOI: 10.7270/Q2348J2G
					More data for this Ligand-Target Pair
Trace amine-associated receptor 7b (Rattus norvegicus (Rat))	BDBM129528 (US8802673, 170) Show SMILES Clc1cc(ccc1Nc1ncc(cn1)C1CC1)[C@@H]1CNCCO1 |r| Show InChI InChI=1S/C17H19ClN4O/c18-14-7-12(16-10-19-5-6-23-16)3-4-15(14)22-17-20-8-13(9-21-17)11-1-2-11/h3-4,7-9,11,16,19H,1-2,5-6,10H2,(H,20,21,22)/t16-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.20	-53.0	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US8802673 (2014) BindingDB Entry DOI: 10.7270/Q2348J2G
					More data for this Ligand-Target Pair
Trace amine-associated receptor 7b (Rattus norvegicus (Rat))	BDBM129507 (US8802673, 149) Show SMILES Clc1cc(ccc1Nc1ncc(cn1)C1CC1)C1CNCCO1 Show InChI InChI=1S/C17H19ClN4O/c18-14-7-12(16-10-19-5-6-23-16)3-4-15(14)22-17-20-8-13(9-21-17)11-1-2-11/h3-4,7-9,11,16,19H,1-2,5-6,10H2,(H,20,21,22)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.40	-52.6	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US8802673 (2014) BindingDB Entry DOI: 10.7270/Q2348J2G
					More data for this Ligand-Target Pair
Trace amine-associated receptor 7b (Rattus norvegicus (Rat))	BDBM129561 (US8802673, 203) Show SMILES FC(F)(F)COc1cnc(Nc2ccc(C3CNCCO3)c(Cl)c2)nc1 Show InChI InChI=1S/C16H16ClF3N4O2/c17-13-5-10(1-2-12(13)14-8-21-3-4-25-14)24-15-22-6-11(7-23-15)26-9-16(18,19)20/h1-2,5-7,14,21H,3-4,8-9H2,(H,22,23,24)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.70	-52.1	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US8802673 (2014) BindingDB Entry DOI: 10.7270/Q2348J2G
					More data for this Ligand-Target Pair
Trace amine-associated receptor 7b (Rattus norvegicus (Rat))	BDBM129542 (US8802673, 184) Show SMILES FC(F)(F)COc1cnc(Nc2ccc(cc2Cl)C2CNCCO2)nc1 Show InChI InChI=1S/C16H16ClF3N4O2/c17-12-5-10(14-8-21-3-4-25-14)1-2-13(12)24-15-22-6-11(7-23-15)26-9-16(18,19)20/h1-2,5-7,14,21H,3-4,8-9H2,(H,22,23,24)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	2	-51.6	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US8802673 (2014) BindingDB Entry DOI: 10.7270/Q2348J2G
					More data for this Ligand-Target Pair
Trace amine-associated receptor 7b (Rattus norvegicus (Rat))	BDBM129562 (US8802673, 204) Show SMILES FC(F)(F)c1cnc(Nc2ccc([C@@H]3CNCCO3)c(Cl)c2)nc1 |r| Show InChI InChI=1S/C15H14ClF3N4O/c16-12-5-10(1-2-11(12)13-8-20-3-4-24-13)23-14-21-6-9(7-22-14)15(17,18)19/h1-2,5-7,13,20H,3-4,8H2,(H,21,22,23)/t13-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	2.10	-51.5	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US8802673 (2014) BindingDB Entry DOI: 10.7270/Q2348J2G
					More data for this Ligand-Target Pair
Trace amine-associated receptor 7b (Rattus norvegicus (Rat))	BDBM129567 (US8802673, 209) Show SMILES Fc1cnc(Nc2ccc(C3CNCCO3)c(F)c2)nc1OCC(F)(F)F Show InChI InChI=1S/C16H15F5N4O2/c17-11-5-9(1-2-10(11)13-7-22-3-4-26-13)24-15-23-6-12(18)14(25-15)27-8-16(19,20)21/h1-2,5-6,13,22H,3-4,7-8H2,(H,23,24,25)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	2.5	-51.1	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US8802673 (2014) BindingDB Entry DOI: 10.7270/Q2348J2G
					More data for this Ligand-Target Pair
Trace amine-associated receptor 7b (Rattus norvegicus (Rat))	BDBM6562 (US8802673, 137) Show SMILES FC(F)(F)COc1cnc(Nc2ccc(cc2)[C@@H]2CNCCO2)nc1 |r| Show InChI InChI=1S/C16H17F3N4O2/c17-16(18,19)10-25-13-7-21-15(22-8-13)23-12-3-1-11(2-4-12)14-9-20-5-6-24-14/h1-4,7-8,14,20H,5-6,9-10H2,(H,21,22,23)/t14-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	2.60	-51.0	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US8802673 (2014) BindingDB Entry DOI: 10.7270/Q2348J2G
					More data for this Ligand-Target Pair
Trace amine-associated receptor 7b (Rattus norvegicus (Rat))	BDBM129550 (US8802673, 192) Show SMILES Fc1cc(Nc2ncc(cn2)C2CC2)ccc1[C@@H]1CNCCO1 |r| Show InChI InChI=1S/C17H19FN4O/c18-15-7-13(3-4-14(15)16-10-19-5-6-23-16)22-17-20-8-12(9-21-17)11-1-2-11/h3-4,7-9,11,16,19H,1-2,5-6,10H2,(H,20,21,22)/t16-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	2.60	-51.0	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US8802673 (2014) BindingDB Entry DOI: 10.7270/Q2348J2G
					More data for this Ligand-Target Pair
Trace amine-associated receptor 7b (Rattus norvegicus (Rat))	BDBM129476 (US8802673, 118) Show SMILES Fc1cc(ccc1Nc1ncc(cn1)C1CC1)[C@@H]1CNCCO1 |r| Show InChI InChI=1S/C17H19FN4O/c18-14-7-12(16-10-19-5-6-23-16)3-4-15(14)22-17-20-8-13(9-21-17)11-1-2-11/h3-4,7-9,11,16,19H,1-2,5-6,10H2,(H,20,21,22)/t16-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	3	-50.6	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US8802673 (2014) BindingDB Entry DOI: 10.7270/Q2348J2G
					More data for this Ligand-Target Pair
Trace amine-associated receptor 7b (Rattus norvegicus (Rat))	BDBM129549 (US8802673, 191) Show SMILES FS(F)(F)(F)(F)c1ccc(Nc2ccc(cc2)[C@@H]2CNCCO2)cc1 |r| Show InChI InChI=1S/C16H17F5N2OS/c17-25(18,19,20,21)15-7-5-14(6-8-15)23-13-3-1-12(2-4-13)16-11-22-9-10-24-16/h1-8,16,22-23H,9-11H2/t16-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.20	-50.4	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US8802673 (2014) BindingDB Entry DOI: 10.7270/Q2348J2G
					More data for this Ligand-Target Pair
Trace amine-associated receptor 7b (Rattus norvegicus (Rat))	BDBM129456 (US8802673, 98) Show SMILES Fc1cc(ccc1Nc1ncc(cn1)C1CC1)C1CNCCO1 Show InChI InChI=1S/C17H19FN4O/c18-14-7-12(16-10-19-5-6-23-16)3-4-15(14)22-17-20-8-13(9-21-17)11-1-2-11/h3-4,7-9,11,16,19H,1-2,5-6,10H2,(H,20,21,22)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	3.30	-50.4	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US8802673 (2014) BindingDB Entry DOI: 10.7270/Q2348J2G
					More data for this Ligand-Target Pair
Trace amine-associated receptor 7b (Rattus norvegicus (Rat))	BDBM129546 (US8802673, 188) Show SMILES Fc1cnc(Nc2ccc(cc2)C2CNCCO2)nc1OCC(F)(F)F Show InChI InChI=1S/C16H16F4N4O2/c17-12-7-22-15(24-14(12)26-9-16(18,19)20)23-11-3-1-10(2-4-11)13-8-21-5-6-25-13/h1-4,7,13,21H,5-6,8-9H2,(H,22,23,24)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	3.30	-50.4	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US8802673 (2014) BindingDB Entry DOI: 10.7270/Q2348J2G
					More data for this Ligand-Target Pair
Trace amine-associated receptor 7b (Rattus norvegicus (Rat))	BDBM129566 (US8802673, 208) Show SMILES Fc1cc(Nc2nccc(OCC(F)(F)F)n2)ccc1C1CNCCO1 Show InChI InChI=1S/C16H16F4N4O2/c17-12-7-10(1-2-11(12)13-8-21-5-6-25-13)23-15-22-4-3-14(24-15)26-9-16(18,19)20/h1-4,7,13,21H,5-6,8-9H2,(H,22,23,24)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	3.5	-50.2	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US8802673 (2014) BindingDB Entry DOI: 10.7270/Q2348J2G
					More data for this Ligand-Target Pair
Trace amine-associated receptor 7b (Rattus norvegicus (Rat))	BDBM129486 (US8802673, 128) Show SMILES CCCc1cnc(Nc2ccc(cc2F)[C@@H]2CNCCO2)nc1 |r| Show InChI InChI=1S/C17H21FN4O/c1-2-3-12-9-20-17(21-10-12)22-15-5-4-13(8-14(15)18)16-11-19-6-7-23-16/h4-5,8-10,16,19H,2-3,6-7,11H2,1H3,(H,20,21,22)/t16-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	3.90	-49.9	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US8802673 (2014) BindingDB Entry DOI: 10.7270/Q2348J2G
					More data for this Ligand-Target Pair
Trace amine-associated receptor 7b (Rattus norvegicus (Rat))	BDBM129554 (US8802673, 196) Show SMILES Fc1cc(Nc2ncc(cn2)C(F)(F)F)ccc1[C@@H]1CNCCO1 |r| Show InChI InChI=1S/C15H14F4N4O/c16-12-5-10(1-2-11(12)13-8-20-3-4-24-13)23-14-21-6-9(7-22-14)15(17,18)19/h1-2,5-7,13,20H,3-4,8H2,(H,21,22,23)/t13-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4	-49.9	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US8802673 (2014) BindingDB Entry DOI: 10.7270/Q2348J2G
					More data for this Ligand-Target Pair
Trace amine-associated receptor 7b (Rattus norvegicus (Rat))	BDBM129459 (US8802673, 101) Show SMILES CCCc1cnc(Nc2ccc(cc2F)C2CNCCO2)nc1 Show InChI InChI=1S/C17H21FN4O/c1-2-3-12-9-20-17(21-10-12)22-15-5-4-13(8-14(15)18)16-11-19-6-7-23-16/h4-5,8-10,16,19H,2-3,6-7,11H2,1H3,(H,20,21,22)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4.10	-49.8	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US8802673 (2014) BindingDB Entry DOI: 10.7270/Q2348J2G
					More data for this Ligand-Target Pair
Trace amine-associated receptor 7b (Rattus norvegicus (Rat))	BDBM129411 (US8802673, 53) Show SMILES Brc1cccc2nc(Nc3ccc(cc3)[C@H]3CNCCO3)ccc12 |r| Show InChI InChI=1S/C19H18BrN3O/c20-16-2-1-3-17-15(16)8-9-19(23-17)22-14-6-4-13(5-7-14)18-12-21-10-11-24-18/h1-9,18,21H,10-12H2,(H,22,23)/t18-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4.5	-49.6	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US8802673 (2014) BindingDB Entry DOI: 10.7270/Q2348J2G
					More data for this Ligand-Target Pair
Trace amine-associated receptor 7b (Rattus norvegicus (Rat))	BDBM129502 (US8802673, 144 | US8802673, 145) Show SMILES Fc1cc(ccc1Nc1ncc(OCC(F)(F)F)cn1)[C@@H]1CNCCO1 |r| Show InChI InChI=1S/C16H16F4N4O2/c17-12-5-10(14-8-21-3-4-25-14)1-2-13(12)24-15-22-6-11(7-23-15)26-9-16(18,19)20/h1-2,5-7,14,21H,3-4,8-9H2,(H,22,23,24)/t14-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4.90	-49.3	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US8802673 (2014) BindingDB Entry DOI: 10.7270/Q2348J2G
					More data for this Ligand-Target Pair
Trace amine-associated receptor 7b (Rattus norvegicus (Rat))	BDBM129477 (US8802673, 119) Show SMILES Fc1cc(ccc1Nc1ncc(cn1)C1CC1)[C@H]1CNCCO1 |r| Show InChI InChI=1S/C17H19FN4O/c18-14-7-12(16-10-19-5-6-23-16)3-4-15(14)22-17-20-8-13(9-21-17)11-1-2-11/h3-4,7-9,11,16,19H,1-2,5-6,10H2,(H,20,21,22)/t16-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	5.10	-49.2	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US8802673 (2014) BindingDB Entry DOI: 10.7270/Q2348J2G
					More data for this Ligand-Target Pair
Trace amine-associated receptor 7b (Rattus norvegicus (Rat))	BDBM129455 (US8802673, 97) Show SMILES CCc1cnc(Nc2ccc(cc2F)C2CNCCO2)nc1 Show InChI InChI=1S/C16H19FN4O/c1-2-11-8-19-16(20-9-11)21-14-4-3-12(7-13(14)17)15-10-18-5-6-22-15/h3-4,7-9,15,18H,2,5-6,10H2,1H3,(H,19,20,21)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	5.60	-49.0	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US8802673 (2014) BindingDB Entry DOI: 10.7270/Q2348J2G
					More data for this Ligand-Target Pair
Trace amine-associated receptor 7b (Rattus norvegicus (Rat))	BDBM129526 (US8802673, 168 | US8802673, 169) Show SMILES FC(F)(F)c1cnc(Nc2ccc(cc2Cl)C2CNCCO2)nc1 Show InChI InChI=1S/C15H14ClF3N4O/c16-11-5-9(13-8-20-3-4-24-13)1-2-12(11)23-14-21-6-10(7-22-14)15(17,18)19/h1-2,5-7,13,20H,3-4,8H2,(H,21,22,23)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	6.5	-48.6	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US8802673 (2014) BindingDB Entry DOI: 10.7270/Q2348J2G
					More data for this Ligand-Target Pair
Trace amine-associated receptor 7b (Rattus norvegicus (Rat))	BDBM129560 (US8802673, 202) Show SMILES Clc1cnc(Nc2ccc([C@@H]3CNCCO3)c(Cl)c2)nc1 |r| Show InChI InChI=1S/C14H14Cl2N4O/c15-9-6-18-14(19-7-9)20-10-1-2-11(12(16)5-10)13-8-17-3-4-21-13/h1-2,5-7,13,17H,3-4,8H2,(H,18,19,20)/t13-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	6.5	-48.6	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US8802673 (2014) BindingDB Entry DOI: 10.7270/Q2348J2G
					More data for this Ligand-Target Pair
Trace amine-associated receptor 7b (Rattus norvegicus (Rat))	BDBM129533 (US8802673, 175) Show SMILES FC(F)Oc1cnc(Oc2cnc(Nc3ccc(cc3Cl)[C@@H]3CNCCO3)nc2)nc1 |r| Show InChI InChI=1S/C19H17ClF2N6O3/c20-14-5-11(16-10-23-3-4-29-16)1-2-15(14)28-18-24-6-13(7-25-18)31-19-26-8-12(9-27-19)30-17(21)22/h1-2,5-9,16-17,23H,3-4,10H2,(H,24,25,28)/t16-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	6.60	-48.6	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US8802673 (2014) BindingDB Entry DOI: 10.7270/Q2348J2G
					More data for this Ligand-Target Pair
Trace amine-associated receptor 7b (Rattus norvegicus (Rat))	BDBM129405 (US8802673, 47) Show SMILES Clc1ccc2nc(Nc3ccc(cc3)[C@H]3CNCCO3)ccc2c1 |r| Show InChI InChI=1S/C19H18ClN3O/c20-15-4-7-17-14(11-15)3-8-19(23-17)22-16-5-1-13(2-6-16)18-12-21-9-10-24-18/h1-8,11,18,21H,9-10,12H2,(H,22,23)/t18-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	6.70	-48.5	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US8802673 (2014) BindingDB Entry DOI: 10.7270/Q2348J2G
					More data for this Ligand-Target Pair
Trace amine-associated receptor 7b (Rattus norvegicus (Rat))	BDBM6564 (US8802673, 145) Show SMILES Fc1cc(ccc1Nc1ncc(OCC(F)(F)F)cn1)[C@H]1CNCCO1 |r| Show InChI InChI=1S/C16H16F4N4O2/c17-12-5-10(14-8-21-3-4-25-14)1-2-13(12)24-15-22-6-11(7-23-15)26-9-16(18,19)20/h1-2,5-7,14,21H,3-4,8-9H2,(H,22,23,24)/t14-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	6.70	-48.5	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US8802673 (2014) BindingDB Entry DOI: 10.7270/Q2348J2G
					More data for this Ligand-Target Pair
Trace amine-associated receptor 7b (Rattus norvegicus (Rat))	BDBM129487 (US8802673, 129) Show SMILES CCCc1cnc(Nc2ccc(cc2F)[C@H]2CNCCO2)nc1 |r| Show InChI InChI=1S/C17H21FN4O/c1-2-3-12-9-20-17(21-10-12)22-15-5-4-13(8-14(15)18)16-11-19-6-7-23-16/h4-5,8-10,16,19H,2-3,6-7,11H2,1H3,(H,20,21,22)/t16-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	6.80	-48.5	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US8802673 (2014) BindingDB Entry DOI: 10.7270/Q2348J2G
					More data for this Ligand-Target Pair
Trace amine-associated receptor 7b (Rattus norvegicus (Rat))	BDBM129474 (US8802673, 116) Show SMILES CCc1cnc(Nc2ccc(cc2F)[C@@H]2CNCCO2)nc1 |r| Show InChI InChI=1S/C16H19FN4O/c1-2-11-8-19-16(20-9-11)21-14-4-3-12(7-13(14)17)15-10-18-5-6-22-15/h3-4,7-9,15,18H,2,5-6,10H2,1H3,(H,19,20,21)/t15-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	7	-48.4	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US8802673 (2014) BindingDB Entry DOI: 10.7270/Q2348J2G
					More data for this Ligand-Target Pair
Trace amine-associated receptor 7b (Rattus norvegicus (Rat))	BDBM6566 (US8802673, 134) Show SMILES Fc1cc(ccc1Nc1ncc(cn1)C(F)(F)F)[C@@H]1CNCCO1 |r| Show InChI InChI=1S/C15H14F4N4O/c16-11-5-9(13-8-20-3-4-24-13)1-2-12(11)23-14-21-6-10(7-22-14)15(17,18)19/h1-2,5-7,13,20H,3-4,8H2,(H,21,22,23)/t13-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	7.90	-48.1	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US8802673 (2014) BindingDB Entry DOI: 10.7270/Q2348J2G
					More data for this Ligand-Target Pair
Trace amine-associated receptor 7b (Rattus norvegicus (Rat))	BDBM129506 (US8802673, 148) Show SMILES C1CO[C@@H](CN1)c1ccc(Nc2ncc(cn2)-c2ccco2)cc1 |r| Show InChI InChI=1S/C18H18N4O2/c1-2-16(23-8-1)14-10-20-18(21-11-14)22-15-5-3-13(4-6-15)17-12-19-7-9-24-17/h1-6,8,10-11,17,19H,7,9,12H2,(H,20,21,22)/t17-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	8.30	-48.0	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US8802673 (2014) BindingDB Entry DOI: 10.7270/Q2348J2G
					More data for this Ligand-Target Pair
Trace amine-associated receptor 7b (Rattus norvegicus (Rat))	BDBM129384 (US8802673, 26) Show SMILES Clc1ccc2nc(Nc3ccc(cc3)[C@H]3CNCCO3)sc2c1 |r| Show InChI InChI=1S/C17H16ClN3OS/c18-12-3-6-14-16(9-12)23-17(21-14)20-13-4-1-11(2-5-13)15-10-19-7-8-22-15/h1-6,9,15,19H,7-8,10H2,(H,20,21)/t15-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	8.30	-48.0	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US8802673 (2014) BindingDB Entry DOI: 10.7270/Q2348J2G
					More data for this Ligand-Target Pair
Trace amine-associated receptor 7b (Rattus norvegicus (Rat))	BDBM129410 (US8802673, 52) Show SMILES Clc1cccc2ccc(Nc3ccc(cc3)[C@H]3CNCCO3)nc12 |r| Show InChI InChI=1S/C19H18ClN3O/c20-16-3-1-2-14-6-9-18(23-19(14)16)22-15-7-4-13(5-8-15)17-12-21-10-11-24-17/h1-9,17,21H,10-12H2,(H,22,23)/t17-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	8.40	-47.9	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US8802673 (2014) BindingDB Entry DOI: 10.7270/Q2348J2G
					More data for this Ligand-Target Pair
Trace amine-associated receptor 7b (Rattus norvegicus (Rat))	BDBM129444 (US8802673, 86) Show SMILES C1CC1c1cnc(Nc2ccc(cc2)[C@@H]2CNCCO2)nc1 |r| Show InChI InChI=1S/C17H20N4O/c1-2-12(1)14-9-19-17(20-10-14)21-15-5-3-13(4-6-15)16-11-18-7-8-22-16/h3-6,9-10,12,16,18H,1-2,7-8,11H2,(H,19,20,21)/t16-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	9	-47.8	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US8802673 (2014) BindingDB Entry DOI: 10.7270/Q2348J2G
					More data for this Ligand-Target Pair
Trace amine-associated receptor 7b (Rattus norvegicus (Rat))	BDBM129420 (US8802673, 62) Show SMILES Cc1cc(Nc2ccc(cc2)[C@H]2CNCCO2)ncc1Br |r| Show InChI InChI=1S/C16H18BrN3O/c1-11-8-16(19-9-14(11)17)20-13-4-2-12(3-5-13)15-10-18-6-7-21-15/h2-5,8-9,15,18H,6-7,10H2,1H3,(H,19,20)/t15-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	9.40	-47.7	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US8802673 (2014) BindingDB Entry DOI: 10.7270/Q2348J2G
					More data for this Ligand-Target Pair
Trace amine-associated receptor 7b (Rattus norvegicus (Rat))	BDBM129484 (US8802673, 126) Show SMILES Fc1cc(ccc1Nc1ncc(Br)cn1)[C@@H]1CNCCO1 |r| Show InChI InChI=1S/C14H14BrFN4O/c15-10-6-18-14(19-7-10)20-12-2-1-9(5-11(12)16)13-8-17-3-4-21-13/h1-2,5-7,13,17H,3-4,8H2,(H,18,19,20)/t13-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	9.60	-47.6	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US8802673 (2014) BindingDB Entry DOI: 10.7270/Q2348J2G
					More data for this Ligand-Target Pair
Trace amine-associated receptor 7b (Rattus norvegicus (Rat))	BDBM129479 (US8802673, 121 | US8802673, 134 | US8802673, 135) Show SMILES Fc1cc(ccc1Nc1ncc(cn1)C(F)(F)F)C1CNCCO1 Show InChI InChI=1S/C15H14F4N4O/c16-11-5-9(13-8-20-3-4-24-13)1-2-12(11)23-14-21-6-10(7-22-14)15(17,18)19/h1-2,5-7,13,20H,3-4,8H2,(H,21,22,23)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	9.60	-47.6	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US8802673 (2014) BindingDB Entry DOI: 10.7270/Q2348J2G
					More data for this Ligand-Target Pair
Trace amine-associated receptor 7b (Rattus norvegicus (Rat))	BDBM129545 (US8802673, 187) Show SMILES FC(F)(F)COc1ccnc(Nc2ccc(cc2)C2CNCCO2)n1 Show InChI InChI=1S/C16H17F3N4O2/c17-16(18,19)10-25-14-5-6-21-15(23-14)22-12-3-1-11(2-4-12)13-9-20-7-8-24-13/h1-6,13,20H,7-10H2,(H,21,22,23)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	10	-47.5	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US8802673 (2014) BindingDB Entry DOI: 10.7270/Q2348J2G
					More data for this Ligand-Target Pair
Trace amine-associated receptor 7b (Rattus norvegicus (Rat))	BDBM129440 (US8802673, 82) Show SMILES FC(F)(F)c1cc(Nc2ccc(cc2)[C@H]2CNCCO2)ncc1Cl |r| Show InChI InChI=1S/C16H15ClF3N3O/c17-13-8-22-15(7-12(13)16(18,19)20)23-11-3-1-10(2-4-11)14-9-21-5-6-24-14/h1-4,7-8,14,21H,5-6,9H2,(H,22,23)/t14-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	10.1	-47.5	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US8802673 (2014) BindingDB Entry DOI: 10.7270/Q2348J2G
					More data for this Ligand-Target Pair
Trace amine-associated receptor 7b (Rattus norvegicus (Rat))	BDBM129565 (US8802673, 207) Show SMILES Fc1cc(Nc2ncc(OCC(F)(F)F)cn2)ccc1C1CNCCO1 Show InChI InChI=1S/C16H16F4N4O2/c17-13-5-10(1-2-12(13)14-8-21-3-4-25-14)24-15-22-6-11(7-23-15)26-9-16(18,19)20/h1-2,5-7,14,21H,3-4,8-9H2,(H,22,23,24)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	10.2	-47.4	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US8802673 (2014) BindingDB Entry DOI: 10.7270/Q2348J2G
					More data for this Ligand-Target Pair
Trace amine-associated receptor 7b (Rattus norvegicus (Rat))	BDBM129475 (US8802673, 117) Show SMILES CCc1cnc(Nc2ccc(cc2F)[C@H]2CNCCO2)nc1 |r| Show InChI InChI=1S/C16H19FN4O/c1-2-11-8-19-16(20-9-11)21-14-4-3-12(7-13(14)17)15-10-18-5-6-22-15/h3-4,7-9,15,18H,2,5-6,10H2,1H3,(H,19,20,21)/t15-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	10.4	-47.4	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US8802673 (2014) BindingDB Entry DOI: 10.7270/Q2348J2G
					More data for this Ligand-Target Pair
Trace amine-associated receptor 7b (Rattus norvegicus (Rat))	BDBM129402 (US8802673, 44) Show SMILES C1CO[C@H](CN1)c1ccc(Nc2ccc3ccccc3c2)cc1 |r| Show InChI InChI=1S/C20H20N2O/c1-2-4-17-13-19(10-5-15(17)3-1)22-18-8-6-16(7-9-18)20-14-21-11-12-23-20/h1-10,13,20-22H,11-12,14H2/t20-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	11.8	-47.1	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US8802673 (2014) BindingDB Entry DOI: 10.7270/Q2348J2G
					More data for this Ligand-Target Pair
Trace amine-associated receptor 7b (Rattus norvegicus (Rat))	BDBM129460 (US8802673, 102) Show SMILES Fc1cc(ccc1Nc1ncc(Br)cn1)C1CNCCO1 Show InChI InChI=1S/C14H14BrFN4O/c15-10-6-18-14(19-7-10)20-12-2-1-9(5-11(12)16)13-8-17-3-4-21-13/h1-2,5-7,13,17H,3-4,8H2,(H,18,19,20)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	12.6	-46.9	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US8802673 (2014) BindingDB Entry DOI: 10.7270/Q2348J2G
					More data for this Ligand-Target Pair
Trace amine-associated receptor 7b (Rattus norvegicus (Rat))	BDBM129499 (US8802673, 141) Show SMILES COc1ccc(cc1OC)-c1cnc(Nc2ccc(cc2)[C@H]2CNCCO2)nc1 |r| Show InChI InChI=1S/C22H24N4O3/c1-27-19-8-5-16(11-20(19)28-2)17-12-24-22(25-13-17)26-18-6-3-15(4-7-18)21-14-23-9-10-29-21/h3-8,11-13,21,23H,9-10,14H2,1-2H3,(H,24,25,26)/t21-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	12.9	-46.8	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US8802673 (2014) BindingDB Entry DOI: 10.7270/Q2348J2G
					More data for this Ligand-Target Pair
Trace amine-associated receptor 7b (Rattus norvegicus (Rat))	BDBM129375 (US8802673, 17) Show SMILES C1CC1c1cnc(Nc2ccc(cc2)[C@H]2CNCCO2)nc1 |r| Show InChI InChI=1S/C17H20N4O/c1-2-12(1)14-9-19-17(20-10-14)21-15-5-3-13(4-6-15)16-11-18-7-8-22-16/h3-6,9-10,12,16,18H,1-2,7-8,11H2,(H,19,20,21)/t16-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	13.1	-46.8	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US8802673 (2014) BindingDB Entry DOI: 10.7270/Q2348J2G
					More data for this Ligand-Target Pair
Trace amine-associated receptor 7b (Rattus norvegicus (Rat))	BDBM129412 (US8802673, 54) Show SMILES Clc1cc(Nc2ccc(cc2)[C@H]2CNCCO2)nc2ccccc12 |r| Show InChI InChI=1S/C19H18ClN3O/c20-16-11-19(23-17-4-2-1-3-15(16)17)22-14-7-5-13(6-8-14)18-12-21-9-10-24-18/h1-8,11,18,21H,9-10,12H2,(H,22,23)/t18-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	13.8	-46.7	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US8802673 (2014) BindingDB Entry DOI: 10.7270/Q2348J2G
					More data for this Ligand-Target Pair
Trace amine-associated receptor 7b (Rattus norvegicus (Rat))	BDBM129500 (US8802673, 142) Show SMILES COc1ccc(cc1OC)-c1cnc(Nc2ccc(cc2)[C@@H]2CNCCO2)nc1 |r| Show InChI InChI=1S/C22H24N4O3/c1-27-19-8-5-16(11-20(19)28-2)17-12-24-22(25-13-17)26-18-6-3-15(4-7-18)21-14-23-9-10-29-21/h3-8,11-13,21,23H,9-10,14H2,1-2H3,(H,24,25,26)/t21-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	14.6	-46.5	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US8802673 (2014) BindingDB Entry DOI: 10.7270/Q2348J2G
					More data for this Ligand-Target Pair
Trace amine-associated receptor 7b (Rattus norvegicus (Rat))	BDBM129530 (US8802673, 172) Show SMILES FC(F)(F)COc1ccnc(Nc2ccc(cc2)[C@@H]2CNCCO2)n1 |r| Show InChI InChI=1S/C16H17F3N4O2/c17-16(18,19)10-25-14-5-6-21-15(23-14)22-12-3-1-11(2-4-12)13-9-20-7-8-24-13/h1-6,13,20H,7-10H2,(H,21,22,23)/t13-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	16.2	-46.3	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US8802673 (2014) BindingDB Entry DOI: 10.7270/Q2348J2G
					More data for this Ligand-Target Pair
Trace amine-associated receptor 7b (Rattus norvegicus (Rat))	BDBM129458 (US8802673, 100) Show SMILES CCOc1cnc(Nc2ccc(cc2F)C2CNCCO2)nc1 Show InChI InChI=1S/C16H19FN4O2/c1-2-22-12-8-19-16(20-9-12)21-14-4-3-11(7-13(14)17)15-10-18-5-6-23-15/h3-4,7-9,15,18H,2,5-6,10H2,1H3,(H,19,20,21)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	16.4	-46.2	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US8802673 (2014) BindingDB Entry DOI: 10.7270/Q2348J2G
					More data for this Ligand-Target Pair

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