Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Signal transducer and activator of transcription 1-alpha/beta/3 (Mus musculus (mouse)-Homo sapiens (Human)) | BDBM20282 (4-{[4-(hexylcarbamoyl)-2-(naphthalen-1-yl)-1,3-oxa...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.20E+4 | n/a | n/a | n/a | n/a | 7.8 | 22 |
University of Central Florida College of Medicine | Assay Description STAT proteins were expressed in Sf9 cells from a baculovirus encoding the recombinant protein. A nuclear extract of the Sf9 cells was incubated with ... | ACS Chem Biol 2: 787-98 (2007) Article DOI: 10.1021/cb7001973 BindingDB Entry DOI: 10.7270/Q29K48HT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 1-alpha/beta/3 (Mus musculus (mouse)-Homo sapiens (Human)) | BDBM20283 (2-hydroxy-4-(2-{[(4-methylbenzene)sulfonyl]oxy}ace...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.60E+5 | n/a | n/a | n/a | n/a | 7.8 | 22 |
University of Central Florida College of Medicine | Assay Description STAT proteins were expressed in Sf9 cells from a baculovirus encoding the recombinant protein. A nuclear extract of the Sf9 cells was incubated with ... | Proc Natl Acad Sci U S A 104: 7391-6 (2007) Article DOI: 10.1073/pnas.0609757104 BindingDB Entry DOI: 10.7270/Q25T3HRN | |||||||||||
More data for this Ligand-Target Pair |