BindingDB PrimarySearch

Found 24 hits Enz. Inhib. hit(s) with Target = 'Ubiquitin carboxyl-terminal hydrolase isozyme L3' AND taxid = 10090
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Mus musculus (Mouse))	BDBM53421 (4-Cyclohexyl-2-phenyl-quinazoline \| 4-cyclohexyl-2...) Show SMILES C1CCC(CC1)c1nc(nc2ccccc12)-c1ccccc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	7.6	25
Brigham and Women's Hospital					Assay Description Inhibition activity and selectivity for UCH-L1 and UCH-L3.				Chem Biol 10: 837-46 (2003) Article DOI: 10.1016/j.chembiol.2003.08.010 BindingDB Entry DOI: 10.7270/Q20Z71P9
Brigham and Women's Hospital					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Mus musculus (Mouse))	BDBM53469 (MLS001209351 \| N-[1-(4-Bromo-phenyl)-ethylidene]-N...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	7.6	25
Brigham and Women's Hospital					Assay Description Inhibition activity and selectivity for UCH-L1 and UCH-L3.				Chem Biol 10: 837-46 (2003) Article DOI: 10.1016/j.chembiol.2003.08.010 BindingDB Entry DOI: 10.7270/Q20Z71P9
Brigham and Women's Hospital					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Mus musculus (Mouse))	BDBM53467 (1,3-Dimethyl-5-nitro-6-[2-(4-propoxy-phenyl)-vinyl...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	7.6	25
Brigham and Women's Hospital					Assay Description Inhibition activity and selectivity for UCH-L1 and UCH-L3.				Chem Biol 10: 837-46 (2003) Article DOI: 10.1016/j.chembiol.2003.08.010 BindingDB Entry DOI: 10.7270/Q20Z71P9
Brigham and Women's Hospital					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Mus musculus (Mouse))	BDBM53470 (2-N,2-N,4-N,4-N-tetraethyl-6-N-(4-nitrophenyl)-1,3...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	7.6	25
Brigham and Women's Hospital					Assay Description Inhibition activity and selectivity for UCH-L1 and UCH-L3.				Chem Biol 10: 837-46 (2003) Article DOI: 10.1016/j.chembiol.2003.08.010 BindingDB Entry DOI: 10.7270/Q20Z71P9
Brigham and Women's Hospital					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Mus musculus (Mouse))	BDBM53443 (2-(3-chloro-4-methoxy-N-methylsulfonylanilino)-N-[...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	7.6	25
Brigham and Women's Hospital					Assay Description Inhibition activity and selectivity for UCH-L1 and UCH-L3.				Chem Biol 10: 837-46 (2003) Article DOI: 10.1016/j.chembiol.2003.08.010 BindingDB Entry DOI: 10.7270/Q20Z71P9
Brigham and Women's Hospital					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Mus musculus (Mouse))	BDBM53468 (2-[3-cyano-4-(2-methoxyphenyl)-6-phenyl-pyridin-2-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	7.6	25
Brigham and Women's Hospital					Assay Description Inhibition activity and selectivity for UCH-L1 and UCH-L3.				Chem Biol 10: 837-46 (2003) Article DOI: 10.1016/j.chembiol.2003.08.010 BindingDB Entry DOI: 10.7270/Q20Z71P9
Brigham and Women's Hospital					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Mus musculus (Mouse))	BDBM53416 ((2S)-2-[[4-[(4-chlorophenyl)carbamoyl]-1H-imidazol...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a	7.6	25
Brigham and Women's Hospital					Assay Description Inhibition activity and selectivity for UCH-L1 and UCH-L3.				Chem Biol 10: 837-46 (2003) Article DOI: 10.1016/j.chembiol.2003.08.010 BindingDB Entry DOI: 10.7270/Q20Z71P9
Brigham and Women's Hospital					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Mus musculus (Mouse))	BDBM53441 (MLS001000876 \| N-(1H-benzimidazol-2-yl)-3-chlorany...) Show SMILES Clc1cccc(c1)C(=O)Nc1nc2ccccc2[nH]1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	7.6	25
Brigham and Women's Hospital					Assay Description Inhibition activity and selectivity for UCH-L1 and UCH-L3.				Chem Biol 10: 837-46 (2003) Article DOI: 10.1016/j.chembiol.2003.08.010 BindingDB Entry DOI: 10.7270/Q20Z71P9
Brigham and Women's Hospital					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Mus musculus (Mouse))	BDBM53442 ((7-chloranyl-3,5-dimethyl-1-benzofuran-2-yl)-(4-ox...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	7.6	25
Brigham and Women's Hospital					Assay Description Inhibition activity and selectivity for UCH-L1 and UCH-L3.				Chem Biol 10: 837-46 (2003) Article DOI: 10.1016/j.chembiol.2003.08.010 BindingDB Entry DOI: 10.7270/Q20Z71P9
Brigham and Women's Hospital					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Mus musculus (Mouse))	BDBM53449 (4-(4-bromophenyl)-2-(o-toluoylamino)-3-thenoic aci...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20E+4	n/a	n/a	n/a	n/a	7.6	25
Brigham and Women's Hospital					Assay Description Inhibition activity and selectivity for UCH-L1 and UCH-L3.				Chem Biol 10: 837-46 (2003) Article DOI: 10.1016/j.chembiol.2003.08.010 BindingDB Entry DOI: 10.7270/Q20Z71P9
Brigham and Women's Hospital					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Mus musculus (Mouse))	BDBM53413 ((2S)-2-[[[4-[(4-methylanilino)-oxomethyl]-1H-imida...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20E+4	n/a	n/a	n/a	n/a	7.6	25
Brigham and Women's Hospital					Assay Description Inhibition activity and selectivity for UCH-L1 and UCH-L3.				Chem Biol 10: 837-46 (2003) Article DOI: 10.1016/j.chembiol.2003.08.010 BindingDB Entry DOI: 10.7270/Q20Z71P9
Brigham and Women's Hospital					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Mus musculus (Mouse))	BDBM53414 ((2S)-4-methyl-2-[[4-(m-tolylcarbamoyl)-1H-imidazol...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30E+4	n/a	n/a	n/a	n/a	7.6	25
Brigham and Women's Hospital					Assay Description Inhibition activity and selectivity for UCH-L1 and UCH-L3.				Chem Biol 10: 837-46 (2003) Article DOI: 10.1016/j.chembiol.2003.08.010 BindingDB Entry DOI: 10.7270/Q20Z71P9
Brigham and Women's Hospital					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Mus musculus (Mouse))	BDBM53445 (2-(4-hydroxy-3-nitro-benzylidene)-3-keto-5-(2-meth...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	7.6	25
Brigham and Women's Hospital					Assay Description Inhibition activity and selectivity for UCH-L1 and UCH-L3.				Chem Biol 10: 837-46 (2003) Article DOI: 10.1016/j.chembiol.2003.08.010 BindingDB Entry DOI: 10.7270/Q20Z71P9
Brigham and Women's Hospital					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Mus musculus (Mouse))	BDBM53482 (1-Butyl-4-hydroxy-2-oxo-1,2-dihydro-quinoline-3-ca...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.10E+4	n/a	n/a	n/a	n/a	7.6	25
Brigham and Women's Hospital					Assay Description Inhibition activity and selectivity for UCH-L1 and UCH-L3.				Chem Biol 10: 837-46 (2003) Article DOI: 10.1016/j.chembiol.2003.08.010 BindingDB Entry DOI: 10.7270/Q20Z71P9
Brigham and Women's Hospital					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Mus musculus (Mouse))	BDBM53447 (4,4'-[1,4-phenylenebis(oxy)]diphenol \| 4-[4-(4...) Show SMILES Oc1ccc(Oc2ccc(Oc3ccc(O)cc3)cc2)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.70E+4	n/a	n/a	n/a	n/a	7.6	25
Brigham and Women's Hospital					Assay Description Inhibition activity and selectivity for UCH-L1 and UCH-L3.				Chem Biol 10: 837-46 (2003) Article DOI: 10.1016/j.chembiol.2003.08.010 BindingDB Entry DOI: 10.7270/Q20Z71P9
Brigham and Women's Hospital					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Mus musculus (Mouse))	BDBM53422 (2,4-Dicyclohexyl-6-methoxy-quinazoline \| 2,4-dicyc...) Show SMILES COc1ccc2nc(nc(C3CCCCC3)c2c1)C1CCCCC1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.70E+4	n/a	n/a	n/a	n/a	7.6	25
Brigham and Women's Hospital					Assay Description Inhibition activity and selectivity for UCH-L1 and UCH-L3.				Chem Biol 10: 837-46 (2003) Article DOI: 10.1016/j.chembiol.2003.08.010 BindingDB Entry DOI: 10.7270/Q20Z71P9
Brigham and Women's Hospital					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Mus musculus (Mouse))	BDBM53419 ((2S)-2-[[4-[(4-methoxyphenyl)carbamoyl]-1H-imidazo...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.80E+4	n/a	n/a	n/a	n/a	7.6	25
Brigham and Women's Hospital					Assay Description Inhibition activity and selectivity for UCH-L1 and UCH-L3.				Chem Biol 10: 837-46 (2003) Article DOI: 10.1016/j.chembiol.2003.08.010 BindingDB Entry DOI: 10.7270/Q20Z71P9
Brigham and Women's Hospital					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Mus musculus (Mouse))	BDBM53454 ((2E)-2-[(2Z)-2-(3-methoxy-4-oxidanylidene-cyclohex...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.20E+4	n/a	n/a	n/a	n/a	7.6	25
Brigham and Women's Hospital					Assay Description Inhibition activity and selectivity for UCH-L1 and UCH-L3.				Chem Biol 10: 837-46 (2003) Article DOI: 10.1016/j.chembiol.2003.08.010 BindingDB Entry DOI: 10.7270/Q20Z71P9
Brigham and Women's Hospital					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Mus musculus (Mouse))	BDBM53415 ((2S)-2-[[4-(m-tolylcarbamoyl)-1H-imidazole-5-carbo...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.20E+4	n/a	n/a	n/a	n/a	7.6	25
Brigham and Women's Hospital					Assay Description Inhibition activity and selectivity for UCH-L1 and UCH-L3.				Chem Biol 10: 837-46 (2003) Article DOI: 10.1016/j.chembiol.2003.08.010 BindingDB Entry DOI: 10.7270/Q20Z71P9
Brigham and Women's Hospital					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Mus musculus (Mouse))	BDBM53418 ((2S)-2-[[[4-[(4-chloroanilino)-oxomethyl]-1H-imida...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.80E+4	n/a	n/a	n/a	n/a	7.6	25
Brigham and Women's Hospital					Assay Description Inhibition activity and selectivity for UCH-L1 and UCH-L3.				Chem Biol 10: 837-46 (2003) Article DOI: 10.1016/j.chembiol.2003.08.010 BindingDB Entry DOI: 10.7270/Q20Z71P9
Brigham and Women's Hospital					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Mus musculus (Mouse))	BDBM24778 (2-methyl-1,4-dihydronaphthalene-1,4-dione \| 2-meth...) Show SMILES CC1=CC(=O)c2ccccc2C1=O \|t:1\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	7.10E+4	n/a	n/a	n/a	n/a	7.6	25
Brigham and Women's Hospital					Assay Description Inhibition activity and selectivity for UCH-L1 and UCH-L3.				Chem Biol 10: 837-46 (2003) Article DOI: 10.1016/j.chembiol.2003.08.010 BindingDB Entry DOI: 10.7270/Q20Z71P9
Brigham and Women's Hospital					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Mus musculus (Mouse))	BDBM53471 ((3-Ethyl-5-hydroxy-5-phenyl-4,5-dihydro-pyrazol-1-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.20E+4	n/a	n/a	n/a	n/a	7.6	25
Brigham and Women's Hospital					Assay Description Inhibition activity and selectivity for UCH-L1 and UCH-L3.				Chem Biol 10: 837-46 (2003) Article DOI: 10.1016/j.chembiol.2003.08.010 BindingDB Entry DOI: 10.7270/Q20Z71P9
Brigham and Women's Hospital					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Mus musculus (Mouse))	BDBM53448 (1-methyl-1-[4-(4-methylphenyl)-6-phenyl-2-pyrimidi...) Show SMILES CN(N)c1nc(cc(n1)-c1ccc(C)cc1)-c1ccccc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.13E+5	n/a	n/a	n/a	n/a	7.6	25
Brigham and Women's Hospital					Assay Description Inhibition activity and selectivity for UCH-L1 and UCH-L3.				Chem Biol 10: 837-46 (2003) Article DOI: 10.1016/j.chembiol.2003.08.010 BindingDB Entry DOI: 10.7270/Q20Z71P9
Brigham and Women's Hospital					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Mus musculus (Mouse))	BDBM53420 ((4S,5S,6R)-1-benzyl-2-keto-6-methyl-4-phenethyl-he...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.16E+5	n/a	n/a	n/a	n/a	7.6	25
Brigham and Women's Hospital					Assay Description Inhibition activity and selectivity for UCH-L1 and UCH-L3.				Chem Biol 10: 837-46 (2003) Article DOI: 10.1016/j.chembiol.2003.08.010 BindingDB Entry DOI: 10.7270/Q20Z71P9
Brigham and Women's Hospital					More data for this Ligand-Target Pair