Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor/Proto-oncogene tyrosine-protein kinase receptor Ret' AND taxid = 9606   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor/Proto-oncogene tyrosine-protein kinase receptor Ret (Homo sapiens (Human))	BDBM24470 (7-methoxy-4-({6-phenyl-[1,2,4]triazolo[4,3-a]pyrid...) Show SMILES COc1ccc2c(OCc3nnc4ccc(nn34)-c3ccccc3)ccnc2c1 Show InChI InChI=1S/C22H17N5O2/c1-28-16-7-8-17-19(13-16)23-12-11-20(17)29-14-22-25-24-21-10-9-18(26-27(21)22)15-5-3-2-4-6-15/h2-13H,14H2,1H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University					Assay Description The c-Met kinase activity as tested with enzyme-linked immunosorbent assays (ELISAs) as previously reported protocol [Qiang et al., Bioorg. Med. Chem...				Bioorg Chem 70: 126-132 (2017) Article DOI: 10.1016/j.bioorg.2016.12.002 BindingDB Entry DOI: 10.7270/Q23X85HP
					More data for this Ligand-Target Pair				3D Structure (crystal)
Hepatocyte growth factor receptor/Proto-oncogene tyrosine-protein kinase receptor Ret (Homo sapiens (Human))	BDBM222078 (6-Chloro-3-((2-(2,4-dichlorophenyl)imidazo[1,2-a]p...) Show SMILES Clc1ccc(-c2cn3cccc(COc4nnc5ccc(Cl)nn45)c3n2)c(Cl)c1 Show InChI InChI=1S/C19H11Cl3N6O/c20-12-3-4-13(14(21)8-12)15-9-27-7-1-2-11(18(27)23-15)10-29-19-25-24-17-6-5-16(22)26-28(17)19/h1-9H,10H2	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.22E+4	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University					Assay Description The c-Met kinase activity as tested with enzyme-linked immunosorbent assays (ELISAs) as previously reported protocol [Qiang et al., Bioorg. Med. Chem...				Bioorg Chem 70: 126-132 (2017) Article DOI: 10.1016/j.bioorg.2016.12.002 BindingDB Entry DOI: 10.7270/Q23X85HP
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor/Proto-oncogene tyrosine-protein kinase receptor Ret (Homo sapiens (Human))	BDBM222077 (6-chloro-3-((2-(2,5-dichlorophenyl)imidazo[1,2-a]p...) Show SMILES Clc1ccc(Cl)c(c1)-c1cn2cccc(COc3nnc4ccc(Cl)nn34)c2n1 Show InChI InChI=1S/C19H11Cl3N6O/c20-12-3-4-14(21)13(8-12)15-9-27-7-1-2-11(18(27)23-15)10-29-19-25-24-17-6-5-16(22)26-28(17)19/h1-9H,10H2	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.23E+4	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University					Assay Description The c-Met kinase activity as tested with enzyme-linked immunosorbent assays (ELISAs) as previously reported protocol [Qiang et al., Bioorg. Med. Chem...				Bioorg Chem 70: 126-132 (2017) Article DOI: 10.1016/j.bioorg.2016.12.002 BindingDB Entry DOI: 10.7270/Q23X85HP
					More data for this Ligand-Target Pair