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| Cell (A) | Syringe (B) | Cell Links | Syringe Links | Cell + Syr Links | ΔG° kJ/mole | -TΔS° kJ/mole | ΔH° kJ/mole | log K | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|
| HIV-1 Protease (Human immunodeficiency virus type 1) | BDBM520 (1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[...) | GoogleScholar PDB | MMDB PC cid PC sid PDB | -60.2 | -44.8 | -15.5 | 10.5 | 5 | 25 | |
The Johns Hopkins University | Biochemistry 42: 631-8 (2003) | |||||||||
| HIV-1 Protease B Subtype (Human immunodeficiency virus type 1) | BDBM520 (1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[...) | GoogleScholar PDB | MMDB PC cid PC sid PDB | -60.2 | -44.8 | -15.5 | 10.5 | 5 | 25 | |
The Johns Hopkins University | Biochemistry 41: 8613-9 (2002) | |||||||||
| HIV-1 Protease (Human immunodeficiency virus type 1) | BDBM520 (1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[...) | GoogleScholar PDB | MMDB PC cid PC sid PDB | -57.3 | -39.3 | -18.0 | 10 | 5 | 25 | |
The Johns Hopkins University | Biochemistry 42: 13659-66 (2003) | |||||||||
| BDBM520 (1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[...) | HIV-1 Protease (Human immunodeficiency virus type 1) | MMDB PC cid PC sid PDB | GoogleScholar PDB | -56.4 | -46.8 | -9.61 | n/a | 5 | 25 | |
The Johns Hopkins University | Biochemistry 39: 11876-83 (2000) | |||||||||
| HIV-1 Protease C Subtype (Human immunodeficiency virus type 1) | BDBM520 (1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[...) | GoogleScholar PDB | MMDB PC cid PC sid PDB | -56.0 | -43.1 | -13.0 | 9.80 | 5 | 25 | |
The Johns Hopkins University | Biochemistry 41: 8613-9 (2002) | |||||||||
| HIV-1 Protease A Subtype (Human immunodeficiency virus type 1) | BDBM520 (1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[...) | GoogleScholar PDB | MMDB PC cid PC sid PDB | -55.2 | -43.1 | -12.1 | 9.65 | 5 | 25 | |
The Johns Hopkins University | Biochemistry 41: 8613-9 (2002) | |||||||||
| HIV-1 Protease Mutant (L10I/L90M) (Human immunodeficiency virus type 1) | BDBM520 (1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[...) | GoogleScholar PDB | MMDB PC cid PC sid PDB | -53.9 | -42.2 | -11.7 | 9.43 | 5 | 25 | |
The Johns Hopkins University | Biochemistry 42: 13659-66 (2003) | |||||||||
| HIV-1 Protease Mutant (M46I/I54V) (Human immunodeficiency virus type 1) | BDBM520 (1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[...) | GoogleScholar PDB | MMDB PC cid PC sid PDB | -53.5 | -57.3 | 3.76 | 9.36 | 5 | 25 | |
The Johns Hopkins University | Biochemistry 42: 13659-66 (2003) | |||||||||
| HIV-1 Protease Mutant, A-1 (Human immunodeficiency virus type 1) | BDBM520 (1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[...) | GoogleScholar PDB | MMDB PC cid PC sid PDB | -50.2 | -50.3 | 0.0836 | 8.80 | 5 | 25 | |
The Johns Hopkins University | Biochemistry 42: 631-8 (2003) | |||||||||
| HIV-1 Protease Mutant (V82A/I84V) (Human immunodeficiency virus type 1) | BDBM520 (1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[...) | GoogleScholar PDB | MMDB PC cid PC sid PDB | -49.7 | -34.7 | -15.0 | 8.70 | 5 | 25 | |
The Johns Hopkins University | Biochemistry 42: 13659-66 (2003) | |||||||||
| HIV-1 Protease B Subtype Mutant (V82F/I84V) (Human immunodeficiency virus type 1) | BDBM520 (1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[...) | GoogleScholar PDB | MMDB PC cid PC sid PDB | -45.6 | -42.6 | -2.93 | 7.95 | 5 | 25 | |
The Johns Hopkins University | Biochemistry 41: 8613-9 (2002) | |||||||||
| HIV-1 Protease Mutant, MDR-QM (Human immunodeficiency virus type 1) | BDBM520 (1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[...) | GoogleScholar PDB | MMDB PC cid PC sid PDB | -44.7 | -58.6 | 13.8 | 7.87 | 5 | 25 | |
The Johns Hopkins University | Biochemistry 42: 13659-66 (2003) | |||||||||
| BDBM520 (1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[...) | HIV-1 Protease Mutant (V82F/I84V) (Human immunodeficiency virus type 1) | MMDB PC cid PC sid PDB | GoogleScholar PDB | -41.8 | -43.9 | 2.09 | n/a | 5 | 25 | |
The Johns Hopkins University | Biochemistry 39: 11876-83 (2000) | |||||||||
| HIV-1 Protease C Subtype Mutant (V82F/I84V) (Human immunodeficiency virus type 1) | BDBM520 (1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[...) | GoogleScholar PDB | MMDB PC cid PC sid PDB | -41.0 | -36.4 | -4.60 | 7.21 | 5 | 25 | |
The Johns Hopkins University | Biochemistry 41: 8613-9 (2002) | |||||||||
| HIV-1 Protease A Subtype Mutant (V82F/I84V) (Human immunodeficiency virus type 1) | BDBM520 (1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[...) | GoogleScholar PDB | MMDB PC cid PC sid PDB | -40.5 | -35.5 | -5.02 | 7.08 | 5 | 25 | |
The Johns Hopkins University | Biochemistry 41: 8613-9 (2002) | |||||||||
| HIV-1 Protease Mutant, MDR-HM (Human immunodeficiency virus type 1) | BDBM520 (1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[...) | GoogleScholar PDB | MMDB PC cid PC sid PDB | -38.9 | -51.0 | 12.1 | 6.83 | 5 | 25 | |
The Johns Hopkins University | Biochemistry 42: 13659-66 (2003) | |||||||||
| HIV-1 Protease Mutant, NAM-10 (Human immunodeficiency virus type 1) | BDBM520 (1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[...) | GoogleScholar | MMDB PC cid PC sid PDB | -36.8 | -27.2 | -9.61 | 6.43 | 5 | 25 | |
The Johns Hopkins University | Biochemistry 42: 631-8 (2003) | |||||||||
| HIV-1 Protease Mutant, ANAM-11 (Human immunodeficiency virus type 1) | BDBM520 (1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[...) | GoogleScholar | MMDB PC cid PC sid PDB | -32.2 | -5.84 | -26.3 | 5.64 | 5 | 25 | |
The Johns Hopkins University | Biochemistry 42: 631-8 (2003) | |||||||||
