Cell (A) | Syringe (B) | Cell Links | Syringe Links | Cell + Syr Links | ΔG° kJ/mole | -TΔS° kJ/mole | ΔH° kJ/mole | log K | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|
HIV-1 Protease (Human immunodeficiency virus type 1) | BDBM520 (1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[...) | GoogleScholar PDB | MMDB PC cid PC sid PDB | -60.2 | -44.8 | -15.5 | 10.5 | 5 | 25 | |
The Johns Hopkins University | Biochemistry 42: 631-8 (2003) | |||||||||
HIV-1 Protease (Human immunodeficiency virus type 1) | BDBM518 ((3S,4aS,8aS)-N-tert-butyl-2-[(2R,3R)-2-hydroxy-3-[...) | GoogleScholar PDB | MMDB PC cid PC sid PDB | -54.8 | -65.7 | 10.9 | 9.59 | 5 | 25 | |
The Johns Hopkins University | Biochemistry 42: 631-8 (2003) | |||||||||
HIV-1 Protease (Human immunodeficiency virus type 1) | BDBM519 ((2S)-N-[(2S,3R)-4-[(3S,4aS,8aS)-3-(tert-butylcarba...) | GoogleScholar PDB | MMDB PC cid PC sid PDB | -53.5 | -61.5 | 7.94 | 9.40 | 5 | 25 | |
The Johns Hopkins University | Biochemistry 42: 631-8 (2003) | |||||||||
HIV-1 Protease (Human immunodeficiency virus type 1) | BDBM517 ((2S)-1-[(2S,4R)-4-benzyl-2-hydroxy-4-{[(1S,2R)-2-h...) | GoogleScholar PDB | MMDB PC cid PC sid PDB | -53.1 | -61.9 | 8.78 | 9.32 | 5 | 25 | |
The Johns Hopkins University | Biochemistry 42: 631-8 (2003) | |||||||||
HIV-1 Protease Mutant, A-1 (Human immunodeficiency virus type 1) | BDBM518 ((3S,4aS,8aS)-N-tert-butyl-2-[(2R,3R)-2-hydroxy-3-[...) | GoogleScholar PDB | MMDB PC cid PC sid PDB | -51.4 | -71.5 | 20.1 | 9.05 | 5 | 25 | |
The Johns Hopkins University | Biochemistry 42: 631-8 (2003) | |||||||||
HIV-1 Protease Mutant, A-1 (Human immunodeficiency virus type 1) | BDBM520 (1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[...) | GoogleScholar PDB | MMDB PC cid PC sid PDB | -50.2 | -50.3 | 0.0836 | 8.80 | 5 | 25 | |
The Johns Hopkins University | Biochemistry 42: 631-8 (2003) | |||||||||
HIV-1 Protease Mutant, A-1 (Human immunodeficiency virus type 1) | BDBM519 ((2S)-N-[(2S,3R)-4-[(3S,4aS,8aS)-3-(tert-butylcarba...) | GoogleScholar PDB | MMDB PC cid PC sid PDB | -50.2 | -75.3 | 25.1 | 8.80 | 5 | 25 | |
The Johns Hopkins University | Biochemistry 42: 631-8 (2003) | |||||||||
HIV-1 Protease Mutant, A-1 (Human immunodeficiency virus type 1) | BDBM517 ((2S)-1-[(2S,4R)-4-benzyl-2-hydroxy-4-{[(1S,2R)-2-h...) | GoogleScholar PDB | MMDB PC cid PC sid PDB | -49.7 | -64.8 | 15.0 | 8.75 | 5 | 25 | |
The Johns Hopkins University | Biochemistry 42: 631-8 (2003) | |||||||||
HIV-1 Protease Mutant, NAM-10 (Human immunodeficiency virus type 1) | BDBM520 (1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[...) | GoogleScholar | MMDB PC cid PC sid PDB | -36.8 | -27.2 | -9.61 | 6.43 | 5 | 25 | |
The Johns Hopkins University | Biochemistry 42: 631-8 (2003) | |||||||||
HIV-1 Protease Mutant, NAM-10 (Human immunodeficiency virus type 1) | BDBM519 ((2S)-N-[(2S,3R)-4-[(3S,4aS,8aS)-3-(tert-butylcarba...) | GoogleScholar | MMDB PC cid PC sid PDB | -36.4 | -63.1 | 26.8 | 6.38 | 5 | 25 | |
The Johns Hopkins University | Biochemistry 42: 631-8 (2003) | |||||||||
HIV-1 Protease Mutant, NAM-10 (Human immunodeficiency virus type 1) | BDBM518 ((3S,4aS,8aS)-N-tert-butyl-2-[(2R,3R)-2-hydroxy-3-[...) | GoogleScholar | MMDB PC cid PC sid PDB | -35.9 | -59.4 | 23.4 | 6.28 | 5 | 25 | |
The Johns Hopkins University | Biochemistry 42: 631-8 (2003) | |||||||||
HIV-1 Protease Mutant, NAM-10 (Human immunodeficiency virus type 1) | BDBM517 ((2S)-1-[(2S,4R)-4-benzyl-2-hydroxy-4-{[(1S,2R)-2-h...) | GoogleScholar | MMDB PC cid PC sid PDB | -35.7 | -61.5 | 25.7 | 6.27 | 5 | 25 | |
The Johns Hopkins University | Biochemistry 42: 631-8 (2003) | |||||||||
HIV-1 Protease Mutant, ANAM-11 (Human immunodeficiency virus type 1) | BDBM518 ((3S,4aS,8aS)-N-tert-butyl-2-[(2R,3R)-2-hydroxy-3-[...) | GoogleScholar | MMDB PC cid PC sid PDB | -34.7 | -50.6 | 15.9 | 6.07 | 5 | 25 | |
The Johns Hopkins University | Biochemistry 42: 631-8 (2003) | |||||||||
HIV-1 Protease Mutant, ANAM-11 (Human immunodeficiency virus type 1) | BDBM517 ((2S)-1-[(2S,4R)-4-benzyl-2-hydroxy-4-{[(1S,2R)-2-h...) | GoogleScholar | MMDB PC cid PC sid PDB | -32.6 | -56.1 | 23.4 | 5.72 | 5 | 25 | |
The Johns Hopkins University | Biochemistry 42: 631-8 (2003) | |||||||||
HIV-1 Protease Mutant, ANAM-11 (Human immunodeficiency virus type 1) | BDBM520 (1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[...) | GoogleScholar | MMDB PC cid PC sid PDB | -32.2 | -5.84 | -26.3 | 5.64 | 5 | 25 | |
The Johns Hopkins University | Biochemistry 42: 631-8 (2003) | |||||||||
HIV-1 Protease Mutant, ANAM-11 (Human immunodeficiency virus type 1) | BDBM519 ((2S)-N-[(2S,3R)-4-[(3S,4aS,8aS)-3-(tert-butylcarba...) | GoogleScholar | MMDB PC cid PC sid PDB | -32.1 | -72.3 | 40.1 | 5.63 | 5 | 25 | |
The Johns Hopkins University | Biochemistry 42: 631-8 (2003) |