Found 27 hits with Target = '3-hydroxy-3-methylglutaryl-coenzyme a reductase (hmg-coa)'| Cell (A) | Syringe (B) | Cell
Links | Syringe
Links | Cell + Syr
Links | ΔG°
kJ/mole | -TΔS°
kJ/mole | ΔH°
kJ/mole | log K | pH | Temp
°C |
|---|
3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA)
(Homo sapiens (Human)) | BDBM24424
((3R,5R)-7-[3-(benzylcarbamoyl)-2-(propan-2-yl)-1H,...) | GoogleScholar
PDB
| KEGG
PC cid
PC sid
| | -41.8 | -13.0 | -28.8 | 7.20 | 7.20 | 30 |
Pfizer Inc.
|
J Med Chem 51: 3804-13 (2008)
|
3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA)
(Homo sapiens (Human)) | BDBM24425
((3R,5R)-7-(2-ethyl-3-{[(4-phenylphenyl)methyl]carb...) | GoogleScholar
PDB
| KEGG
PC cid
PC sid
| | -42.6 | -21.3 | -21.7 | 7.39 | 7.20 | 30 |
Pfizer Inc.
|
J Med Chem 51: 3804-13 (2008)
|
3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA)
(Homo sapiens (Human)) | BDBM24415
((3R,5R)-7-[4-(benzylcarbamoyl)-2-(3,4-difluorophen...) | GoogleScholar
PDB
| KEGG
PC cid
PC sid
| | -47.2 | 19.2 | -66.5 | 8.16 | 7.20 | 30 |
Pfizer Inc.
|
J Med Chem 51: 3804-13 (2008)
|
3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA)
(Homo sapiens (Human)) | BDBM24416
((3R,5R)-7-[2-(4-fluorophenyl)-4-{[(4-phenylphenyl)...) | GoogleScholar
PDB
| KEGG
PC cid
PC sid
| | -46.4 | 17.1 | -63.5 | 8.01 | 7.20 | 30 |
Pfizer Inc.
|
J Med Chem 51: 3804-13 (2008)
|
3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA)
(Homo sapiens (Human)) | BDBM24435
((3R,5R)-7-[3-(4-fluorophenyl)-8-oxo-7-phenyl-1-(pr...) | GoogleScholar
PDB
| KEGG
MMDB
PC cid
PC sid
PDB
| | -44.3 | -11.3 | -33.0 | 7.67 | 7.20 | 30 |
Pfizer Inc.
|
J Med Chem 51: 3804-13 (2008)
|
3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA)
(Homo sapiens (Human)) | BDBM24436
((3R,5R)-7-[2,3-bis(4-fluorophenyl)-4-{[4-(methoxyc...) | GoogleScholar
PDB
| KEGG
PC cid
PC sid
| | -40.5 | 15.5 | -56.4 | 7.02 | 7.20 | 30 |
Pfizer Inc.
|
J Med Chem 51: 3804-13 (2008)
|
3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA)
(Homo sapiens (Human)) | BDBM24437
((3R,5R)-7-[2-(4-fluorophenyl)-4-(morpholin-4-ylsul...) | GoogleScholar
PDB
| KEGG
PC cid
PC sid
| | -44.3 | 10.5 | -55.2 | 7.67 | 7.20 | 30 |
Pfizer Inc.
|
J Med Chem 51: 3804-13 (2008)
|
3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA)
(Homo sapiens (Human)) | BDBM24438
((3R,5R)-7-[2,3-bis(4-fluorophenyl)-4-{[4-(2-methox...) | GoogleScholar
PDB
| KEGG
PC cid
PC sid
| | -42.6 | 11.7 | -54.3 | 7.37 | 7.20 | 30 |
Pfizer Inc.
|
J Med Chem 51: 3804-13 (2008)
|
3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA)
(Homo sapiens (Human)) | BDBM18372
((3R,5S,6E)-7-[4-(4-fluorophenyl)-2-(N-methylmethan...) | GoogleScholar
PDB
| CHEBI
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
| | -45.1 | 10.0 | -55.2 | 7.77 | 7.20 | 30 |
Pfizer Inc.
|
J Med Chem 51: 3804-13 (2008)
|
3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA)
(Homo sapiens (Human)) | BDBM24417
((3R,5R)-7-[2-(4-fluorophenyl)-4-{[(1S)-2-hydroxy-1...) | GoogleScholar
PDB
| KEGG
MMDB
PC cid
PC sid
PDB
| | -42.2 | 18.8 | -61.0 | 7.29 | 7.20 | 30 |
Pfizer Inc.
|
J Med Chem 51: 3804-13 (2008)
|
3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA)
(Homo sapiens (Human)) | BDBM24418
((3R,5R)-7-[2-(4-fluorophenyl)-4-{methyl[(1S)-1-phe...) | GoogleScholar
PDB
| KEGG
PC cid
PC sid
| | -47.2 | 12.1 | -58.9 | 8.12 | 7.20 | 30 |
Pfizer Inc.
|
J Med Chem 51: 3804-13 (2008)
|
3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA)
(Homo sapiens (Human)) | BDBM24419
((3R,5R)-7-[2-(4-fluorophenyl)-4-({[3-(2-fluorophen...) | GoogleScholar
PDB
| KEGG
PC cid
PC sid
| | -44.3 | -7.09 | -37.2 | 7.66 | 7.20 | 30 |
Pfizer Inc.
|
J Med Chem 51: 3804-13 (2008)
|
3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA)
(Homo sapiens (Human)) | BDBM24420
((3R,5R)-7-[4-(4-fluorophenyl)-2-{[(3-fluorophenyl)...) | GoogleScholar
PDB
| KEGG
PC cid
PC sid
| | -43.9 | 30.1 | -74.0 | 7.57 | 7.20 | 30 |
Pfizer Inc.
|
J Med Chem 51: 3804-13 (2008)
|
3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA)
(Homo sapiens (Human)) | BDBM24421
((3R,5R)-7-[2-(benzylcarbamoyl)-4-(4-fluorophenyl)-...) | GoogleScholar
PDB
| KEGG
PC cid
PC sid
| | -43.5 | 25.1 | -68.6 | 7.50 | 7.20 | 30 |
Pfizer Inc.
|
J Med Chem 51: 3804-13 (2008)
|
3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA)
(Homo sapiens (Human)) | BDBM24422
((3R,5R)-7-(2-ethyl-3-{[(4-phenylphenyl)methyl]carb...) | GoogleScholar
PDB
| KEGG
PC cid
PC sid
| | -45.6 | -11.3 | -34.7 | 7.90 | 7.20 | 30 |
Pfizer Inc.
|
J Med Chem 51: 3804-13 (2008)
|
3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA)
(Homo sapiens (Human)) | BDBM24423
((3R,5R)-3,5-dihydroxy-7-(3-{[(1S)-2-hydroxy-1-phen...) | GoogleScholar
PDB
| KEGG
PC cid
PC sid
| | -43.1 | -11.3 | -31.8 | 7.46 | 7.20 | 30 |
Pfizer Inc.
|
J Med Chem 51: 3804-13 (2008)
|
3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA)
(Homo sapiens (Human)) | BDBM18373
(3-Hydroxy-3-methylglutaryl-CoA | HMG-CoA) | GoogleScholar
PDB
| KEGG
PC cid
PC sid
PDB
| | -28.0 | 10.0 | -38.0 | 4.84 | 7.20 | 30 |
Pfizer Inc.
|
J Med Chem 51: 3804-13 (2008)
|
3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA)
(Homo sapiens (Human)) | BDBM24426
((3R,5R)-7-[2-(4-fluorophenyl)-4-[(2-hydroxyphenyl)...) | GoogleScholar
PDB
| CHEBI
KEGG
MMDB
PC cid
PC sid
PDB
| | -43.9 | 5.03 | -48.9 | 7.56 | 7.20 | 30 |
Pfizer Inc.
|
J Med Chem 51: 3804-13 (2008)
|
3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA)
(Homo sapiens (Human)) | BDBM24427
((3R,5R)-7-[2-ethyl-5-(4-fluorophenyl)-3-(phenylcar...) | GoogleScholar
PDB
| KEGG
PC cid
PC sid
| | -41.4 | 1.67 | -43.1 | 7.16 | 7.20 | 30 |
Pfizer Inc.
|
J Med Chem 51: 3804-13 (2008)
|
3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA)
(Homo sapiens (Human)) | BDBM24428
((3R,5R)-7-[3-(4-fluorophenyl)-1-methyl-4-phenyl-5-...) | GoogleScholar
PDB
| KEGG
PC cid
PC sid
| | -43.9 | 13.0 | -57.3 | 7.58 | 7.20 | 30 |
Pfizer Inc.
|
J Med Chem 51: 3804-13 (2008)
|
3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA)
(Homo sapiens (Human)) | BDBM24429
((3R,5R)-7-[3-(4-fluorophenyl)-4-methyl-5-(phenylca...) | GoogleScholar
PDB
| KEGG
PC cid
PC sid
| | -47.7 | 8.79 | -56.4 | 8.21 | 7.20 | 30 |
Pfizer Inc.
|
J Med Chem 51: 3804-13 (2008)
|
3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA)
(Homo sapiens (Human)) | BDBM24430
((3R,5R)-7-(5-{[4-(dimethylcarbamoyl)phenyl]carbamo...) | GoogleScholar
PDB
| KEGG
PC cid
PC sid
| | -48.1 | 6.70 | -54.8 | 8.27 | 7.20 | 30 |
Pfizer Inc.
|
J Med Chem 51: 3804-13 (2008)
|
3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA)
(Homo sapiens (Human)) | BDBM24431
((3R,5R)-7-[3-(4-fluorophenyl)-1-methyl-5-{[(5-meth...) | GoogleScholar
PDB
| KEGG
PC cid
PC sid
| | -45.6 | 5.43 | -51.0 | 7.85 | 7.20 | 30 |
Pfizer Inc.
|
J Med Chem 51: 3804-13 (2008)
|
3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA)
(Homo sapiens (Human)) | BDBM24432
((3R,5R)-7-[3-(4-fluorophenyl)-5-{[4-(methoxycarbon...) | GoogleScholar
PDB
| KEGG
PC cid
PC sid
| | -46.4 | 3.76 | -50.2 | 8.03 | 7.20 | 30 |
Pfizer Inc.
|
J Med Chem 51: 3804-13 (2008)
|
3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA)
(Homo sapiens (Human)) | BDBM24433
((3R,5R)-7-[3,4-bis(4-fluorophenyl)-1-methyl-5-(phe...) | GoogleScholar
PDB
| KEGG
PC cid
PC sid
| | -45.6 | 2.09 | -47.7 | 7.84 | 7.20 | 30 |
Pfizer Inc.
|
J Med Chem 51: 3804-13 (2008)
|
3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA)
(Homo sapiens (Human)) | BDBM24434
((3R,5R)-7-[3,4-bis(4-fluorophenyl)-1-methyl-5-[(3-...) | GoogleScholar
PDB
| KEGG
PC cid
PC sid
| | -49.3 | -3.76 | -45.6 | 8.49 | 7.20 | 30 |
Pfizer Inc.
|
J Med Chem 51: 3804-13 (2008)
|
3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA)
(Homo sapiens (Human)) | BDBM24414
((3R,5R)-7-[4-(benzylcarbamoyl)-2-(4-fluorophenyl)-...) | GoogleScholar
PDB
| KEGG
MMDB
PC cid
PC sid
PDB
| | -45.6 | 28.0 | -74.0 | 7.87 | 7.20 | 30 |
Pfizer Inc.
|
J Med Chem 51: 3804-13 (2008)
|
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