Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Beta-glucuronidase (Homo sapiens (Human)) | BDBM163636 (3[(6,8Dimethyl2oxo1,2dihydroquinolin3 yl)methyl]1(...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | n/a | 17.7 | n/a | n/a | n/a | n/a |
The University of North Carolina at Chapel Hill US Patent | Assay Description PNPG Assay: Two ß-glucuronidase activity assays were employed to examine the potency of inhibitors both in vitro and in cell-based studies. An absorb... | US Patent US9334288 (2016) BindingDB Entry DOI: 10.7270/Q270809V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-glucuronidase (Escherichia coli (Enterobacteria)) | BDBM163636 (3[(6,8Dimethyl2oxo1,2dihydroquinolin3 yl)methyl]1(...) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 18 | n/a | n/a | n/a | n/a |
University of KwaZulu-Natal Curated by ChEMBL | Assay Description Inhibition of Escherichia coli beta-glucuronidase using p-nitrophenyl-beta-D-glucuronide as substrate | Eur J Med Chem 187: (2020) Article DOI: 10.1016/j.ejmech.2019.111921 BindingDB Entry DOI: 10.7270/Q29W0K1V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-glucuronidase (Homo sapiens (Human)) | BDBM163636 (3[(6,8Dimethyl2oxo1,2dihydroquinolin3 yl)methyl]1(...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | n/a | 29 | n/a | n/a | n/a | n/a |
The University of North Carolina at Chapel Hill US Patent | Assay Description PheG Assay: Two ß-glucuronidase activity assays were employed to examine the potency of inhibitors both in vitro and in cell-based studies. An absorb... | US Patent US9334288 (2016) BindingDB Entry DOI: 10.7270/Q270809V | |||||||||||
More data for this Ligand-Target Pair |