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Compile Data Set for Download or QSAR

Found 1 hit of ec50 for monomerid = 168488   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Endothelin-1


(Homo sapiens (Human))		BDBM168488
PNG
(US9675593, 50)
Show SMILES Cn1cc(cn1)-c1cn(-c2ccc(OC(F)(F)F)cc2)c(=O)c2N(Cc3ccccc3)C(=O)COc12
Show InChI InChI=1S/C25H19F3N4O4/c1-30-13-17(11-29-30)20-14-31(18-7-9-19(10-8-18)36-25(26,27)28)24(34)22-23(20)35-15-21(33)32(22)12-16-5-3-2-4-6-16/h2-11,13-14H,12,15H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>2.00E+5n/an/an/an/a



SRMLSC

US Patent


Assay Description
Fibroblasts (primary human lung and dermal, HFL-1, 3T3 etc) are seeded in 96-well plates at ~15000 cells/well and serum starved for 0-48 hours. After...

US Patent US9675593 (2017)


BindingDB Entry DOI: 10.7270/Q2319T24
More data for this
Ligand-Target Pair