Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Androgen receptor (Homo sapiens (Human)) | BDBM18692 ((2S)-N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-f...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 31 | n/a | n/a | n/a | n/a |
University of Maryland Curated by ChEMBL | Assay Description Displacement of [3H]R1881 from AR in human MDA-MB-453 cells | J Med Chem 56: 4880-98 (2013) Article DOI: 10.1021/jm400048v BindingDB Entry DOI: 10.7270/Q2445NWN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Homo sapiens (Human)) | BDBM18692 ((2S)-N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-f...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a |
University of Maryland Curated by ChEMBL | Assay Description Displacement of [3H]R1881 from AR in human LNCaP cells after 2 hrs by scintillation counting analysis | J Med Chem 56: 4880-98 (2013) Article DOI: 10.1021/jm400048v BindingDB Entry DOI: 10.7270/Q2445NWN | |||||||||||
More data for this Ligand-Target Pair |