BindingDB PrimarySearch

Found 5 hits of ec50 for monomerid = 20608
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Estrogen receptor beta (RAT-Rattus norvegicus)	BDBM20608 (4-Hydroxytamoxifen \| 4-Hydroxytamoxifen (9) \| 4-[(...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	n/a	n/a	6	n/a	n/a	n/a	n/a
University of Georgia Curated by ChEMBL					Assay Description In vitro displacement of 3 nM [3H]4-hydroxytamoxifen from estrogen receptor of rat uterine cystol				J Med Chem 31: 1471-5 (1988) BindingDB Entry DOI: 10.7270/Q2DN478W
University of Georgia Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Estrogen receptor (Homo sapiens (Human))	BDBM20608 (4-Hydroxytamoxifen \| 4-Hydroxytamoxifen (9) \| 4-[(...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	17	n/a	10.3	n/a	n/a	7.4	22
Novartis Pharmaceuticals					Assay Description Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...				J Med Chem 46: 2945-57 (2003) Article DOI: 10.1021/jm030086h BindingDB Entry DOI: 10.7270/Q2H41PQQ
Novartis Pharmaceuticals					More data for this Ligand-Target Pair				3D Structure (crystal)
Estrogen-related receptor gamma (Homo sapiens (Human))	BDBM20608 (4-Hydroxytamoxifen \| 4-Hydroxytamoxifen (9) \| 4-[(...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	n/a	n/a	n/a	n/a	15	n/a	n/a	7.0	22
GSK					Assay Description Recruitment of the RIP140 NR-box peptide to the ERRgamma ligand binding domain was assayed by FRET detection. Proteins were set up in a one to one ra...				J Med Chem 48: 3107-9 (2005) Article DOI: 10.1021/jm050161j BindingDB Entry DOI: 10.7270/Q2S46Q77
GSK					More data for this Ligand-Target Pair				3D Structure (crystal)
Estrogen receptor (Homo sapiens (Human))	BDBM20608 (4-Hydroxytamoxifen \| 4-Hydroxytamoxifen (9) \| 4-[(...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	n/a	n/a	16	n/a	n/a	n/a	n/a
The Ohio State University Curated by ChEMBL					Assay Description Binding affinity for Estrogen receptor alpha				Bioorg Med Chem Lett 13: 1475-8 (2003) BindingDB Entry DOI: 10.7270/Q2KD1X9M
The Ohio State University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Estrogen receptor beta (Homo sapiens (Human))	BDBM20608 (4-Hydroxytamoxifen \| 4-Hydroxytamoxifen (9) \| 4-[(...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	21	n/a	32	n/a	n/a	n/a	25
Novartis Pharmaceuticals					Assay Description Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...				J Med Chem 46: 2945-57 (2003) Article DOI: 10.1021/jm030086h BindingDB Entry DOI: 10.7270/Q2H41PQQ
Novartis Pharmaceuticals					More data for this Ligand-Target Pair				3D Structure (crystal)