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Compile Data Set for Download or QSAR

Found 1 hit of ec50 for monomerid = 209183   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Bcl-2-like protein 1


(Mus musculus (Mouse))		BDBM209183
PNG
(US9266877, 129)
Show SMILES Cc1c(cc(C#N)n1Cc1ccccc1)-c1ccc(nc1C(O)=O)N1CCc2cccc(C(=O)Nc3nc4ccccc4s3)c2C1
Show InChI InChI=1S/C36H28N6O3S/c1-22-28(18-25(19-37)42(22)20-23-8-3-2-4-9-23)26-14-15-32(39-33(26)35(44)45)41-17-16-24-10-7-11-27(29(24)21-41)34(43)40-36-38-30-12-5-6-13-31(30)46-36/h2-15,18H,16-17,20-21H2,1H3,(H,44,45)(H,38,40,43)
PDB

UniProtKB/SwissProt

B.MOAD
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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 18n/an/an/an/a



ABBVIE INC.

US Patent


Assay Description
The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...

US Patent US9266877 (2016)


BindingDB Entry DOI: 10.7270/Q2H41Q7V
More data for this
Ligand-Target Pair