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Compile Data Set for Download or QSAR

Found 1 hit of ec50 for monomerid = 209214   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Bcl-2-like protein 1


(Mus musculus (Mouse))		BDBM209214
PNG
(US9266877, 160)
Show SMILES Cc1c(cnn1CC1(CCCCC1)N1CCOCC1)-c1ccc(nc1C(O)=O)N1CCc2cccc(C(=O)Nc3nc4ccccc4s3)c2C1
Show InChI InChI=1S/C38H41N7O4S/c1-25-29(22-39-45(25)24-38(15-5-2-6-16-38)44-18-20-49-21-19-44)27-12-13-33(41-34(27)36(47)48)43-17-14-26-8-7-9-28(30(26)23-43)35(46)42-37-40-31-10-3-4-11-32(31)50-37/h3-4,7-13,22H,2,5-6,14-21,23-24H2,1H3,(H,47,48)(H,40,42,46)
PDB

UniProtKB/SwissProt

B.MOAD
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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 14n/an/an/an/a



ABBVIE INC.

US Patent


Assay Description
The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...

US Patent US9266877 (2016)


BindingDB Entry DOI: 10.7270/Q2H41Q7V
More data for this
Ligand-Target Pair