BindingDB PrimarySearch

Found 32 hits of ec50 for monomerid = 24183
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Gamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-2 (Homo sapiens (Human))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	230	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Agonist activity at recombinant human GABA-A alpha5beta2gamma2S receptor transiently expressed in human tsA201 cells incubated for 30 mins and measur...				J Med Chem 62: 5797-5809 (2019) Article DOI: 10.1021/acs.jmedchem.9b00026 BindingDB Entry DOI: 10.7270/Q2D2222H
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-2 (Homo sapiens (Human))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	234	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Agonist activity at recombinant human GABA-A alpha5beta2gamma2S receptor transiently expressed in human tsA201 cells incubated for 30 mins and measur...				J Med Chem 62: 5797-5809 (2019) Article DOI: 10.1021/acs.jmedchem.9b00026 BindingDB Entry DOI: 10.7270/Q2D2222H
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit rho-1 (Homo sapiens (Human))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	269	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Agonist activity at human GABAA rho1 expressed in tsA-201cells by FLIPR membrane potential blue assay				Eur J Med Chem 84: 404-16 (2014) Article DOI: 10.1016/j.ejmech.2014.07.039 BindingDB Entry DOI: 10.7270/Q2QV3P4Z
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit rho-1 (Homo sapiens (Human))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	270	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Agonist activity at human GABAA rho1 receptor expressed in TSA201 cells after 1 min by FLIPR assay				J Med Chem 56: 993-1006 (2013) Article DOI: 10.1021/jm301473k BindingDB Entry DOI: 10.7270/Q2W37XMM
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit rho-1 (Homo sapiens (Human))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	270	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Agonist activity at human GABAA rho1 expressed in tsA-201cells by FLIPR membrane potential blue assay				Eur J Med Chem 84: 404-16 (2014) Article DOI: 10.1016/j.ejmech.2014.07.039 BindingDB Entry DOI: 10.7270/Q2QV3P4Z
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit rho-1 (Homo sapiens (Human))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	339	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Agonist activity at recombinant human GABA-A rho-1 receptor transiently expressed in human tsA201 cells incubated for 30 mins and measured up to 90 s...				J Med Chem 62: 5797-5809 (2019) Article DOI: 10.1021/acs.jmedchem.9b00026 BindingDB Entry DOI: 10.7270/Q2D2222H
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit rho-1 (Homo sapiens (Human))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	340	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Agonist activity at recombinant human GABA-A rho-1 receptor transiently expressed in human tsA201 cells incubated for 30 mins and measured up to 90 s...				J Med Chem 62: 5797-5809 (2019) Article DOI: 10.1021/acs.jmedchem.9b00026 BindingDB Entry DOI: 10.7270/Q2D2222H
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid type B receptor subunit 1/2 (Homo sapiens (Human))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	530	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...				J Med Chem 56: 2456-65 (2013) Article DOI: 10.1021/jm301805e BindingDB Entry DOI: 10.7270/Q25T3MTS
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2 (Homo sapiens (Human))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	650	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Agonist activity at human GABAAalpha2beta2gamma2S receptor expressed in tsA-201cells by FLIPR membrane potential blue assay				Eur J Med Chem 84: 404-16 (2014) Article DOI: 10.1016/j.ejmech.2014.07.039 BindingDB Entry DOI: 10.7270/Q2QV3P4Z
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2 (Homo sapiens (Human))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	661	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Agonist activity at human GABAAalpha2beta2gamma2S receptor expressed in tsA-201cells by FLIPR membrane potential blue assay				Eur J Med Chem 84: 404-16 (2014) Article DOI: 10.1016/j.ejmech.2014.07.039 BindingDB Entry DOI: 10.7270/Q2QV3P4Z
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit rho-1 (Homo sapiens (Human))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	800	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Agonist activity at human GABAc Rho1 receptor expressed in Xenopus oocytes assessed as whole cell current production by two electrode voltage clamp m...				J Med Chem 51: 3825-40 (2008) Article DOI: 10.1021/jm7015842 BindingDB Entry DOI: 10.7270/Q27M07RR
University of Sydney Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit alpha-3/beta-2/gamma-2 (Homo sapiens (Human))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	912	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Agonist activity at human GABAAalpha3beta2gamma2S receptor expressed in tsA-201cells by FLIPR membrane potential blue assay				Eur J Med Chem 84: 404-16 (2014) Article DOI: 10.1016/j.ejmech.2014.07.039 BindingDB Entry DOI: 10.7270/Q2QV3P4Z
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit alpha-3/beta-2/gamma-2 (Homo sapiens (Human))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	920	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Agonist activity at human GABAAalpha3beta2gamma2S receptor expressed in tsA-201cells by FLIPR membrane potential blue assay				Eur J Med Chem 84: 404-16 (2014) Article DOI: 10.1016/j.ejmech.2014.07.039 BindingDB Entry DOI: 10.7270/Q2QV3P4Z
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit rho-1 (Homo sapiens (Human))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
The University of Sydney Curated by ChEMBL					Assay Description Agonist activity at GABAC rho1 receptor (unknown origin)				ACS Med Chem Lett 4: 402-7 (2013) Article DOI: 10.1021/ml300476v BindingDB Entry DOI: 10.7270/Q27H1KXG
The University of Sydney Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit rho-1 (Homo sapiens (Human))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	1.19E+3	n/a	n/a	n/a	n/a
The University of Sydney Curated by ChEMBL					Assay Description Agonist activity at human recombinant GABAc rho1 receptor expressed in Xenopus laevis oocytes at -60mV by two-electrode voltage clamp method				Bioorg Med Chem Lett 18: 402-4 (2008) Article DOI: 10.1016/j.bmcl.2007.10.019 BindingDB Entry DOI: 10.7270/Q2TT4RTQ
The University of Sydney Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit alpha-6/beta-3/gamma-2 (Homo sapiens (Human))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Antagonistic potency against human Gamma-aminobutyric-acid A receptor alpha2-beta3-gamma2 expressed in Xenopus oocytes at 1 mM				Bioorg Med Chem Lett 11: 1573-7 (2001) BindingDB Entry DOI: 10.7270/Q24J0DDQ
The Royal Danish School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid type B receptor subunit 1 (Homo sapiens (Human))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Agonist activity at human GABAb 1A/2 receptor expressed in Xenopus oocytes assessed as whole cell current production by two electrode voltage clamp m...				J Med Chem 51: 3825-40 (2008) Article DOI: 10.1021/jm7015842 BindingDB Entry DOI: 10.7270/Q27M07RR
University of Sydney Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Homo sapiens (Human))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	1.78E+3	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Agonist activity at human GABAAalpha1beta2gamma2S receptor expressed in tsA-201cells by FLIPR membrane potential blue assay				Eur J Med Chem 84: 404-16 (2014) Article DOI: 10.1016/j.ejmech.2014.07.039 BindingDB Entry DOI: 10.7270/Q2QV3P4Z
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Homo sapiens (Human))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Agonist activity at human GABAAalpha1beta2gamma2S receptor expressed in tsA-201cells by FLIPR membrane potential blue assay				Eur J Med Chem 84: 404-16 (2014) Article DOI: 10.1016/j.ejmech.2014.07.039 BindingDB Entry DOI: 10.7270/Q2QV3P4Z
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Effective agonist dose for human Gamma-aminobutyric-acid A receptor alpha4-beta3-gamma2				Bioorg Med Chem Lett 11: 1573-7 (2001) BindingDB Entry DOI: 10.7270/Q24J0DDQ
The Royal Danish School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit alpha-4/beta-2/gamma-2 (Homo sapiens (Human))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Agonist activity at recombinant human GABA-A alpha4beta2gamma2S receptor transiently expressed in human tsA201 cells incubated for 30 mins and measur...				J Med Chem 62: 5797-5809 (2019) Article DOI: 10.1021/acs.jmedchem.9b00026 BindingDB Entry DOI: 10.7270/Q2D2222H
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Homo sapiens (Human))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Agonist activity at recombinant human GABA-A alpha1beta2gamma2S receptor transiently expressed in human tsA201 cells incubated for 30 mins and measur...				J Med Chem 62: 5797-5809 (2019) Article DOI: 10.1021/acs.jmedchem.9b00026 BindingDB Entry DOI: 10.7270/Q2D2222H
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit alpha-4/beta-2/gamma-2 (Homo sapiens (Human))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	3.72E+3	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Agonist activity at recombinant human GABA-A alpha4beta2gamma2S receptor transiently expressed in human tsA201 cells incubated for 30 mins and measur...				J Med Chem 62: 5797-5809 (2019) Article DOI: 10.1021/acs.jmedchem.9b00026 BindingDB Entry DOI: 10.7270/Q2D2222H
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Homo sapiens (Human))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Agonist activity at recombinant human GABA-A alpha1beta2gamma2S receptor transiently expressed in human tsA201 cells incubated for 30 mins and measur...				J Med Chem 62: 5797-5809 (2019) Article DOI: 10.1021/acs.jmedchem.9b00026 BindingDB Entry DOI: 10.7270/Q2D2222H
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit alpha-1 (Rattus norvegicus (Rat))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a
Johannes Gutenberg-UniVersity Curated by ChEMBL					Assay Description Activity at rat wild type GABAAalpha1beta2 receptor expressed in Xenopus laevis oocytes at -60 mV by Two-Electrode voltage clamp method				J Med Chem 51: 4430-48 (2008) Article DOI: 10.1021/jm701562x BindingDB Entry DOI: 10.7270/Q2FF3S6G
Johannes Gutenberg-UniVersity Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2 (Homo sapiens (Human))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	n/a	n/a	2.80E+4	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Effective agonist dose for human Gamma-aminobutyric-acid A receptor alpha6-beta3-gamma2				Bioorg Med Chem Lett 11: 1573-7 (2001) BindingDB Entry DOI: 10.7270/Q24J0DDQ
The Royal Danish School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
GABA-A receptor; alpha-2/beta-3/gamma-2 (Homo sapiens (Human))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Effective agonist dose for human Gamma-aminobutyric-acid A receptor alpha6-beta3-gamma2				Bioorg Med Chem Lett 11: 1573-7 (2001) BindingDB Entry DOI: 10.7270/Q24J0DDQ
The Royal Danish School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Homo sapiens (Human))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	4.30E+4	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Agonist activity at GABA alpha-1-beta-2-gamma-2 receptor expressed in HEK293 cells by Whole-cell patch-clamp technique				J Med Chem 50: 4147-61 (2007) Article DOI: 10.1021/jm070447j BindingDB Entry DOI: 10.7270/Q2KK9BGK
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
GABA A receptor alpha-4/beta-3/gamma-2 (Homo sapiens (Human))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Effective agonist dose for human Gamma-aminobutyric-acid A receptor alpha5-beta3-gamma2 expressed in Xenopus oocytes				Bioorg Med Chem Lett 11: 1573-7 (2001) BindingDB Entry DOI: 10.7270/Q24J0DDQ
The Royal Danish School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Homo sapiens (Human))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	5.10E+4	n/a	n/a	n/a	n/a
University of Graz Curated by ChEMBL					Assay Description Partial agonist activity at GABAAalpha1beta2gamma2s receptor (unknown origin) expressed in Xenopus laevis oocytes assessed as induction of chloride c...				Bioorg Med Chem 23: 6757-62 (2015) Article DOI: 10.1016/j.bmc.2015.08.034 BindingDB Entry DOI: 10.7270/Q2WQ05KM
University of Graz Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	8.00E+4	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Agonist activity on human Gamma-aminobutyric-acid A receptor alpha3-beta3-gamma2 expressed in Xenopus oocytes				Bioorg Med Chem Lett 11: 1573-7 (2001) BindingDB Entry DOI: 10.7270/Q24J0DDQ
The Royal Danish School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Heat shock factor protein 1 (Mus musculus)	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PCBioAssay	n/a	n/a	n/a	n/a	>1.95E+5	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2MW2FKX
Broad Institute Curated by PubChem BioAssay					More data for this Ligand-Target Pair