BindingDB PrimarySearch

Found 9 hits of ec50 for monomerid = 50004863
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50004863 ((+/-)-trans-ACPD \| (1S,3S)-1-Amino-cyclopentane-1,...) Show SMILES N[C@]1(CC[C@@H](C1)C(O)=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a
Université René Descartes-Paris V Curated by ChEMBL					Assay Description Agonist activity against Metabotropic glutamate receptor 2 expressed in HEK 293 cells was evaluated by measuring total inositol phosphate accumulatio...				J Med Chem 40: 3119-29 (1997) Article DOI: 10.1021/jm970207b BindingDB Entry DOI: 10.7270/Q200016Q
Université René Descartes-Paris V Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50004863 ((+/-)-trans-ACPD \| (1S,3S)-1-Amino-cyclopentane-1,...) Show SMILES N[C@]1(CC[C@@H](C1)C(O)=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Compound was tested for the inhibition of metabotropic glutamate receptor 2 (mGluR2).				J Med Chem 41: 1641-50 (1998) Article DOI: 10.1021/jm970719q BindingDB Entry DOI: 10.7270/Q27945BZ
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Homo sapiens (Human))	BDBM50004863 ((+/-)-trans-ACPD \| (1S,3S)-1-Amino-cyclopentane-1,...) Show SMILES N[C@]1(CC[C@@H](C1)C(O)=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Compound was tested for the inhibition of Metabotropic glutamate receptor 3 (mGluR3)				J Med Chem 41: 1641-50 (1998) Article DOI: 10.1021/jm970719q BindingDB Entry DOI: 10.7270/Q27945BZ
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50004863 ((+/-)-trans-ACPD \| (1S,3S)-1-Amino-cyclopentane-1,...) Show SMILES N[C@]1(CC[C@@H](C1)C(O)=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	4.80E+4	n/a	n/a	n/a	n/a
Université René Descartes-Paris V Curated by ChEMBL					Assay Description Agonist activity against Metabotropic glutamate receptor 4 expressed in HEK 293 cells was evaluated by measuring total inositol phosphate accumulatio...				J Med Chem 40: 3119-29 (1997) Article DOI: 10.1021/jm970207b BindingDB Entry DOI: 10.7270/Q200016Q
Université René Descartes-Paris V Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50004863 ((+/-)-trans-ACPD \| (1S,3S)-1-Amino-cyclopentane-1,...) Show SMILES N[C@]1(CC[C@@H](C1)C(O)=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Compound was tested for the inhibition of Metabotropic glutamate receptor 4				J Med Chem 41: 1641-50 (1998) Article DOI: 10.1021/jm970719q BindingDB Entry DOI: 10.7270/Q27945BZ
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM50004863 ((+/-)-trans-ACPD \| (1S,3S)-1-Amino-cyclopentane-1,...) Show SMILES N[C@]1(CC[C@@H](C1)C(O)=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Universit£ Ren£ Descartes-Paris V Curated by ChEMBL					Assay Description Stimulation of [3H]phosphatidylinositol accumulation by rat Metabotropic glutamate receptor 4 co-expressed with Gqi9 protein in HEK 293 cells; Inacti...				J Med Chem 48: 2534-47 (2005) Article DOI: 10.1021/jm049092j BindingDB Entry DOI: 10.7270/Q23X87FM
Universit£ Ren£ Descartes-Paris V Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50004863 ((+/-)-trans-ACPD \| (1S,3S)-1-Amino-cyclopentane-1,...) Show SMILES N[C@]1(CC[C@@H](C1)C(O)=O)C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Compound was tested for the inhibition of Metabotropic glutamate receptor 5				J Med Chem 41: 1641-50 (1998) Article DOI: 10.1021/jm970719q BindingDB Entry DOI: 10.7270/Q27945BZ
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50004863 ((+/-)-trans-ACPD \| (1S,3S)-1-Amino-cyclopentane-1,...) Show SMILES N[C@]1(CC[C@@H](C1)C(O)=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a
Université René Descartes-Paris V Curated by ChEMBL					Assay Description Agonist activity against Metabotropic glutamate receptor 1 expressed in HEK 293 cells was evaluated by measuring total inositol phosphate accumulatio...				J Med Chem 40: 3119-29 (1997) Article DOI: 10.1021/jm970207b BindingDB Entry DOI: 10.7270/Q200016Q
Université René Descartes-Paris V Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50004863 ((+/-)-trans-ACPD \| (1S,3S)-1-Amino-cyclopentane-1,...) Show SMILES N[C@]1(CC[C@@H](C1)C(O)=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Compound was tested for the inhibition of Metabotropic glutamate receptor 1				J Med Chem 41: 1641-50 (1998) Article DOI: 10.1021/jm970719q BindingDB Entry DOI: 10.7270/Q27945BZ
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair