Compile Data Set for Download or QSAR

Found 10 hits of ec50 for monomerid = 50042874   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM50042874 (2,2'-Bipyridin | 2,2'-bipyridine | 2,2'-bipyridyl ...) Show SMILES c1ccc(nc1)-c1ccccn1 Show InChI InChI=1S/C10H8N2/c1-3-7-11-9(5-1)10-6-2-4-8-12-10/h1-8H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	320	n/a	n/a	n/a	n/a
Johns Hopkins University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human methionine aminopeptidase 1 in presence of Co2+				J Med Chem 56: 3996-4016 (2013) Article DOI: 10.1021/jm400227z BindingDB Entry DOI: 10.7270/Q2SJ1N1Z
					More data for this Ligand-Target Pair
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50042874 (2,2'-Bipyridin | 2,2'-bipyridine | 2,2'-bipyridyl ...) Show SMILES c1ccc(nc1)-c1ccccn1 Show InChI InChI=1S/C10H8N2/c1-3-7-11-9(5-1)10-6-2-4-8-12-10/h1-8H	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Allosteric modulation at human CCR5 transfected in COS7 cells coexpressing chimeric Gqi4myr assessed as [3H]IP3 turnover by liquid scintillation coun...				J Med Chem 55: 8164-77 (2012) Article DOI: 10.1021/jm301121j BindingDB Entry DOI: 10.7270/Q2Q81F7S
					More data for this Ligand-Target Pair
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50042874 (2,2'-Bipyridin | 2,2'-bipyridine | 2,2'-bipyridyl ...) Show SMILES c1ccc(nc1)-c1ccccn1 Show InChI InChI=1S/C10H8N2/c1-3-7-11-9(5-1)10-6-2-4-8-12-10/h1-8H	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Allosteric modulation at human CCR5 transfected in COS7 cells coexpressing chimeric Gqi4myr assessed as [3H]IP3 turnover by liquid scintillation coun...				J Med Chem 55: 8164-77 (2012) Article DOI: 10.1021/jm301121j BindingDB Entry DOI: 10.7270/Q2Q81F7S
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50042874 (2,2'-Bipyridin | 2,2'-bipyridine | 2,2'-bipyridyl ...) Show SMILES c1ccc(nc1)-c1ccccn1 Show InChI InChI=1S/C10H8N2/c1-3-7-11-9(5-1)10-6-2-4-8-12-10/h1-8H	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	3.16E+4	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Allosteric modulation at human CCR1 transfected in COS7 cells coexpressing chimeric Gqi4myr assessed as {3H]IP3 turnover by liquid scintillation coun...				J Med Chem 55: 8164-77 (2012) Article DOI: 10.1021/jm301121j BindingDB Entry DOI: 10.7270/Q2Q81F7S
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50042874 (2,2'-Bipyridin | 2,2'-bipyridine | 2,2'-bipyridyl ...) Show SMILES c1ccc(nc1)-c1ccccn1 Show InChI InChI=1S/C10H8N2/c1-3-7-11-9(5-1)10-6-2-4-8-12-10/h1-8H	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	3.40E+4	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Allosteric modulation at human CCR1 transfected in COS7 cells coexpressing chimeric Gqi4myr assessed as {3H]IP3 turnover by liquid scintillation coun...				J Med Chem 55: 8164-77 (2012) Article DOI: 10.1021/jm301121j BindingDB Entry DOI: 10.7270/Q2Q81F7S
					More data for this Ligand-Target Pair
C-C chemokine receptor type 8 (Homo sapiens (Human))	BDBM50042874 (2,2'-Bipyridin | 2,2'-bipyridine | 2,2'-bipyridyl ...) Show SMILES c1ccc(nc1)-c1ccccn1 Show InChI InChI=1S/C10H8N2/c1-3-7-11-9(5-1)10-6-2-4-8-12-10/h1-8H	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	3.98E+4	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Allosteric modulation at human CCR8 transfected in COS7 cells assessed as [3H]IP3 turnover by liquid scintillation counting analysis				J Med Chem 55: 8164-77 (2012) Article DOI: 10.1021/jm301121j BindingDB Entry DOI: 10.7270/Q2Q81F7S
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50042874 (2,2'-Bipyridin | 2,2'-bipyridine | 2,2'-bipyridyl ...) Show SMILES c1ccc(nc1)-c1ccccn1 Show InChI InChI=1S/C10H8N2/c1-3-7-11-9(5-1)10-6-2-4-8-12-10/h1-8H	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	US Patent	n/a	n/a	n/a	n/a	4.14E+4	n/a	n/a	n/a	n/a
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China US Patent					Assay Description The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...				US Patent US10196346 (2019) BindingDB Entry DOI: 10.7270/Q2VQ34SQ
					More data for this Ligand-Target Pair
C-C chemokine receptor type 8 (Homo sapiens (Human))	BDBM50042874 (2,2'-Bipyridin | 2,2'-bipyridine | 2,2'-bipyridyl ...) Show SMILES c1ccc(nc1)-c1ccccn1 Show InChI InChI=1S/C10H8N2/c1-3-7-11-9(5-1)10-6-2-4-8-12-10/h1-8H	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	4.20E+4	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Allosteric modulation at human CCR8 transfected in COS7 cells assessed as [3H]IP3 turnover by liquid scintillation counting analysis				J Med Chem 55: 8164-77 (2012) Article DOI: 10.1021/jm301121j BindingDB Entry DOI: 10.7270/Q2Q81F7S
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM50042874 (2,2'-Bipyridin | 2,2'-bipyridine | 2,2'-bipyridyl ...) Show SMILES c1ccc(nc1)-c1ccccn1 Show InChI InChI=1S/C10H8N2/c1-3-7-11-9(5-1)10-6-2-4-8-12-10/h1-8H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Johns Hopkins University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human methionine aminopeptidase 1 in presence of Zn2+				J Med Chem 56: 3996-4016 (2013) Article DOI: 10.1021/jm400227z BindingDB Entry DOI: 10.7270/Q2SJ1N1Z
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM50042874 (2,2'-Bipyridin | 2,2'-bipyridine | 2,2'-bipyridyl ...) Show SMILES c1ccc(nc1)-c1ccccn1 Show InChI InChI=1S/C10H8N2/c1-3-7-11-9(5-1)10-6-2-4-8-12-10/h1-8H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Johns Hopkins University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human methionine aminopeptidase 1 in presence of Mn2+				J Med Chem 56: 3996-4016 (2013) Article DOI: 10.1021/jm400227z BindingDB Entry DOI: 10.7270/Q2SJ1N1Z
					More data for this Ligand-Target Pair