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Compile Data Set for Download or QSAR

Found 1 hit of ec50 for monomerid = 50055070   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Kappa-type opioid receptor


(Homo sapiens (Human))		BDBM50055070
PNG
(CHEMBL3323518)
Show SMILES Clc1ccc(CC(=O)N2CCN(C3CCCC(C23)N2CCCC2)C(=O)c2ccccc2)cc1Cl
Show InChI InChI=1S/C27H31Cl2N3O2/c28-21-12-11-19(17-22(21)29)18-25(33)32-16-15-31(27(34)20-7-2-1-3-8-20)24-10-6-9-23(26(24)32)30-13-4-5-14-30/h1-3,7-8,11-12,17,23-24,26H,4-6,9-10,13-16,18H2
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PubMed
n/an/an/an/a 260n/an/an/an/a



Westf£lische Wilhelms-Universit£t M£nster

Curated by ChEMBL


Assay Description
Agonist activity at human kappa opioid receptor expressed in HEK-293 cells assessed as stimulation of [35S]-GTPgammaS binding after 30 mins by liquid...

J Med Chem 57: 6845-60 (2014)


Article DOI: 10.1021/jm500940q
BindingDB Entry DOI: 10.7270/Q2G73GDP
More data for this
Ligand-Target Pair