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Compile Data Set for Download or QSAR

Found 1 hit of ec50 for monomerid = 50055079   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Kappa-type opioid receptor


(Homo sapiens (Human))		BDBM50055079
PNG
(CHEMBL3323526)
Show SMILES COC(=O)CC(=O)N1CCN(C2C(CCCC12)N1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C24H31Cl2N3O4/c1-33-23(32)15-22(31)28-11-12-29(21(30)14-16-7-8-17(25)18(26)13-16)24-19(5-4-6-20(24)28)27-9-2-3-10-27/h7-8,13,19-20,24H,2-6,9-12,14-15H2,1H3
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Article
PubMed
n/an/an/an/a 220n/an/an/an/a



Westf£lische Wilhelms-Universit£t M£nster

Curated by ChEMBL


Assay Description
Agonist activity at human kappa opioid receptor expressed in HEK-293 cells assessed as stimulation of [35S]-GTPgammaS binding after 30 mins by liquid...

J Med Chem 57: 6845-60 (2014)


Article DOI: 10.1021/jm500940q
BindingDB Entry DOI: 10.7270/Q2G73GDP
More data for this
Ligand-Target Pair