Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Replicase polyprotein 1ab (2019-nCoV) | BDBM50069985 ((S)-4-methyl-2-(3-phenyl-propionylamino)-pentanoic...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article | n/a | n/a | n/a | n/a | 120 | n/a | n/a | n/a | n/a |
Fraunhofer Institute for Translational Medicine and Pharmacology (ITMP) and Fraunhofer Cluster of Excellence for Immune mediated diseases (CIMD) | Assay Description anti-cytopathic effect in a Vero-E6 cell line. | bioRxiv 2020: (2020) Article DOI: 10.1101/2020.12.16.422677 BindingDB Entry DOI: 10.7270/Q26M39VR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NF-kappa-B inhibitor alpha (Homo sapiens (Human)) | BDBM50069985 ((S)-4-methyl-2-(3-phenyl-propionylamino)-pentanoic...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a |
Columbia University Curated by ChEMBL | Assay Description Induction of human IkappaBalpha stabilization in OCI-Ly3 cells by green light emiting IkappaBalpha-fused luciferase reporter gene assay | Bioorg Med Chem Lett 18: 329-35 (2008) Article DOI: 10.1016/j.bmcl.2007.10.100 BindingDB Entry DOI: 10.7270/Q2348M63 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NF-kappa-B inhibitor alpha (Homo sapiens (Human)) | BDBM50069985 ((S)-4-methyl-2-(3-phenyl-propionylamino)-pentanoic...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 5.20E+3 | n/a | n/a | n/a | n/a |
Columbia University Curated by ChEMBL | Assay Description Induction of human IkappaBalpha stabilization in OCI-Ly3 cells assessed as ratio of green light emiting IkappaBalpha-fused luciferase expression to r... | Bioorg Med Chem Lett 18: 329-35 (2008) Article DOI: 10.1016/j.bmcl.2007.10.100 BindingDB Entry DOI: 10.7270/Q2348M63 | |||||||||||
More data for this Ligand-Target Pair |