Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human)) | BDBM50085046 (2-((S)-1-carboxy-2-{4-[2-(5-methyl-2-phenyl-oxazol...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.617 | n/a | n/a | n/a | n/a |
Glaxo Wellcome Research and Development Curated by ChEMBL | Assay Description -log concentration required to induce 50% maximum lipogenic activity against Peroxisome proliferator activated receptor gamma | J Med Chem 41: 5055-69 (1998) Article DOI: 10.1021/jm980414r BindingDB Entry DOI: 10.7270/Q2DB84MJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human)) | BDBM50085046 (2-((S)-1-carboxy-2-{4-[2-(5-methyl-2-phenyl-oxazol...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.630 | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Transactivation of human PPARgamma in CV-1 cells by GAL4 reporter assay | Bioorg Med Chem Lett 17: 3916-20 (2007) Checked by Author Article DOI: 10.1016/j.bmcl.2007.04.111 BindingDB Entry DOI: 10.7270/Q2R49S33 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human)) | BDBM50085046 (2-((S)-1-carboxy-2-{4-[2-(5-methyl-2-phenyl-oxazol...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article | n/a | n/a | n/a | n/a | 0.708 | n/a | n/a | n/a | n/a |
TBA | Assay Description Transactivation of Homo sapiens (human) PPARgamma assessed as luciferase activity by reporter gene assay | Citation and Details Article DOI: 10.1007/s00044-011-9818-7 BindingDB Entry DOI: 10.7270/Q2R49TNP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human)) | BDBM50085046 (2-((S)-1-carboxy-2-{4-[2-(5-methyl-2-phenyl-oxazol...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.708 | n/a | n/a | n/a | n/a |
Glaxo Wellcome Research and Development Curated by ChEMBL | Assay Description in vitro agonist activity against peroxisome proliferator activated receptor-gamma (PPAR-gamma), using alkaline phosphatase activity transactivator a... | J Med Chem 41: 5055-69 (1998) Article DOI: 10.1021/jm980414r BindingDB Entry DOI: 10.7270/Q2DB84MJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human)) | BDBM50085046 (2-((S)-1-carboxy-2-{4-[2-(5-methyl-2-phenyl-oxazol...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | 0.710 | n/a | n/a | n/a | n/a |
Glaxo Wellcome Research & Development Curated by ChEMBL | Assay Description Agonist activity for Human PPAR gamma receptor in transcriptional activation assay | J Med Chem 43: 527-50 (2000) BindingDB Entry DOI: 10.7270/Q2H994DT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human)) | BDBM50085046 (2-((S)-1-carboxy-2-{4-[2-(5-methyl-2-phenyl-oxazol...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | 0.710 | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Maximal reporter activity against human Peroxisome proliferator activated receptor gamma Gal4 chimeric in transiently transfected CV-1 cells by funct... | Bioorg Med Chem Lett 11: 3111-3 (2001) BindingDB Entry DOI: 10.7270/Q2B27TKM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor gamma (Mus musculus) | BDBM50085046 (2-((S)-1-carboxy-2-{4-[2-(5-methyl-2-phenyl-oxazol...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a |
Glaxo Wellcome Research & Development Curated by ChEMBL | Assay Description Agonist activity for murine PPAR gamma receptor in transcriptional activation assay | J Med Chem 43: 527-50 (2000) BindingDB Entry DOI: 10.7270/Q2H994DT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human)) | BDBM50085046 (2-((S)-1-carboxy-2-{4-[2-(5-methyl-2-phenyl-oxazol...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article | n/a | n/a | n/a | n/a | 3.47E+3 | n/a | n/a | n/a | n/a |
TBA | Assay Description Transactivation of Homo sapiens (human) PPARalpha assessed as luciferase activity by reporter gene assay | Citation and Details Article DOI: 10.1007/s00044-011-9818-7 BindingDB Entry DOI: 10.7270/Q2R49TNP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human)) | BDBM50085046 (2-((S)-1-carboxy-2-{4-[2-(5-methyl-2-phenyl-oxazol...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a |
Glaxo Wellcome Research & Development Curated by ChEMBL | Assay Description Agonist activity for Human PPAR alpha receptor in transcriptional activation assay | J Med Chem 43: 527-50 (2000) BindingDB Entry DOI: 10.7270/Q2H994DT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human)) | BDBM50085046 (2-((S)-1-carboxy-2-{4-[2-(5-methyl-2-phenyl-oxazol...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Binding affinity to human Peroxisome proliferator activated receptor alpha using scintillation proximity assay | Bioorg Med Chem Lett 11: 3111-3 (2001) BindingDB Entry DOI: 10.7270/Q2B27TKM | |||||||||||
More data for this Ligand-Target Pair |