BindingDB PrimarySearch

Found 5 hits of ec50 for monomerid = 50157304
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
NAD-dependent protein deacetylase sirtuin-3, mitochondrial (Homo sapiens (Human))	BDBM50157304 (3',5-di-2-propenyl-1,1'-biphenyl-2,4'-diol \| 3',5-...) Show SMILES Oc1ccc(cc1CC=C)-c1cc(CC=C)ccc1O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	170	n/a	n/a	n/a	n/a
TBA					Assay Description Activation of recombinant human SIRT3 assessed as lysyl deacetylase activity using (Gln-Pro-Lys-Lys(Ac)) peptide substrate by fluorescent assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02268 BindingDB Entry DOI: 10.7270/Q2H9991Z
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50157304 (3',5-di-2-propenyl-1,1'-biphenyl-2,4'-diol \| 3',5-...) Show SMILES Oc1ccc(cc1CC=C)-c1cc(CC=C)ccc1O Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Agonist activity at recombinant human CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 5 mins ...				ACS Med Chem Lett 4: 41-5 (2013) Article DOI: 10.1021/ml300235q BindingDB Entry DOI: 10.7270/Q2SF2XHW
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM50157304 (3',5-di-2-propenyl-1,1'-biphenyl-2,4'-diol \| 3',5-...) Show SMILES Oc1ccc(cc1CC=C)-c1cc(CC=C)ccc1O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.18E+4	n/a	n/a	n/a	n/a
Aichi Gakuin University Curated by ChEMBL					Assay Description Agonist activity at RXRalpha in HEK293 cells assessed as transcriptional activation after 48 hrs by luciferase reporter gene assay				J Nat Prod 73: 1332-6 (2010) Article DOI: 10.1021/np100120c BindingDB Entry DOI: 10.7270/Q2VT1S9K
Aichi Gakuin University Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2 (Homo sapiens (Human))	BDBM50157304 (3',5-di-2-propenyl-1,1'-biphenyl-2,4'-diol \| 3',5-...) Show SMILES Oc1ccc(cc1CC=C)-c1cc(CC=C)ccc1O Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	3.93E+4	n/a	n/a	n/a	n/a
University of Vienna Curated by ChEMBL					Assay Description Modulation of GABA Aalpha1beta2 receptor expressed in Xenopus laevis oocytes assessed as potentiation of GABA-induced chloride current at holding pot...				J Med Chem 54: 5349-61 (2011) Article DOI: 10.1021/jm200186n BindingDB Entry DOI: 10.7270/Q2QR4XGP
University of Vienna Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Homo sapiens (Human))	BDBM50157304 (3',5-di-2-propenyl-1,1'-biphenyl-2,4'-diol \| 3',5-...) Show SMILES Oc1ccc(cc1CC=C)-c1cc(CC=C)ccc1O Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	7.62E+4	n/a	n/a	n/a	n/a
University of Graz Curated by ChEMBL					Assay Description Partial agonist activity at GABAAalpha1beta2gamma2s receptor (unknown origin) expressed in Xenopus laevis oocytes assessed as induction of chloride c...				Bioorg Med Chem 23: 6757-62 (2015) Article DOI: 10.1016/j.bmc.2015.08.034 BindingDB Entry DOI: 10.7270/Q2WQ05KM
University of Graz Curated by ChEMBL					More data for this Ligand-Target Pair