Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mu-type opioid receptor (Homo sapiens (Human)) | BDBM50182939 ((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-1-((S...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 2 | n/a | n/a | n/a | n/a |
Janssen Research and Development, L.L.C. Curated by ChEMBL | Assay Description Binding affinity to human mu opioid receptor | Bioorg Med Chem Lett 22: 4869-72 (2012) Article DOI: 10.1016/j.bmcl.2012.05.042 BindingDB Entry DOI: 10.7270/Q2F76DP8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (GUINEA PIG) | BDBM50182939 ((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-1-((S...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 2 | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL | Assay Description Activity against mu opioid receptor by stimulation of [35S]GTPgammaS binding in CHO-hgamma cells | Bioorg Med Chem Lett 16: 2505-8 (2006) Article DOI: 10.1016/j.bmcl.2006.01.082 BindingDB Entry DOI: 10.7270/Q29G5MDZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (MOUSE) | BDBM50182939 ((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-1-((S...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 37 | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL | Assay Description Activity against delta opioid receptor by stimulation of [35S]GTPgammaS binding in CHO-hgamma cells | Bioorg Med Chem Lett 16: 2505-8 (2006) Article DOI: 10.1016/j.bmcl.2006.01.082 BindingDB Entry DOI: 10.7270/Q29G5MDZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Homo sapiens (Human)) | BDBM50182939 ((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-1-((S...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 37 | n/a | n/a | n/a | n/a |
Janssen Research and Development, L.L.C. Curated by ChEMBL | Assay Description Agonist activity at delta opioid receptor expressed in CHO-hg cells by [35S]-GTPgammaS binding assay | Bioorg Med Chem Lett 22: 4869-72 (2012) Article DOI: 10.1016/j.bmcl.2012.05.042 BindingDB Entry DOI: 10.7270/Q2F76DP8 | |||||||||||
More data for this Ligand-Target Pair |