Compile Data Set for Download or QSAR

Found 6 hits of ec50 for monomerid = 50272345   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 2 (Rattus norvegicus (Rat))	BDBM50272345 (CHEMBL499059 | N-(2-tert-Butylpyrimidin-5-yl)-3-(3...) Show SMILES CC(C)(C)c1ncc(NC(=O)CCc2nc(no2)-c2ccc(F)cc2Cl)cn1 Show InChI InChI=1S/C19H19ClFN5O2/c1-19(2,3)18-22-9-12(10-23-18)24-15(27)6-7-16-25-17(26-28-16)13-5-4-11(21)8-14(13)20/h4-5,8-10H,6-7H2,1-3H3,(H,24,27)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.30	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at rat recombinant CB2 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP level				J Med Chem 51: 5019-34 (2008) Article DOI: 10.1021/jm800463f BindingDB Entry DOI: 10.7270/Q2W096VS
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50272345 (CHEMBL499059 | N-(2-tert-Butylpyrimidin-5-yl)-3-(3...) Show SMILES CC(C)(C)c1ncc(NC(=O)CCc2nc(no2)-c2ccc(F)cc2Cl)cn1 Show InChI InChI=1S/C19H19ClFN5O2/c1-19(2,3)18-22-9-12(10-23-18)24-15(27)6-7-16-25-17(26-28-16)13-5-4-11(21)8-14(13)20/h4-5,8-10H,6-7H2,1-3H3,(H,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.90	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human recombinant CB2 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP level				J Med Chem 51: 5019-34 (2008) Article DOI: 10.1021/jm800463f BindingDB Entry DOI: 10.7270/Q2W096VS
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50272345 (CHEMBL499059 | N-(2-tert-Butylpyrimidin-5-yl)-3-(3...) Show SMILES CC(C)(C)c1ncc(NC(=O)CCc2nc(no2)-c2ccc(F)cc2Cl)cn1 Show InChI InChI=1S/C19H19ClFN5O2/c1-19(2,3)18-22-9-12(10-23-18)24-15(27)6-7-16-25-17(26-28-16)13-5-4-11(21)8-14(13)20/h4-5,8-10H,6-7H2,1-3H3,(H,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	5.40	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human recombinant CB2 receptor expressed in Sf9 cells by GTP-europium binding assay				J Med Chem 51: 5019-34 (2008) Article DOI: 10.1021/jm800463f BindingDB Entry DOI: 10.7270/Q2W096VS
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50272345 (CHEMBL499059 | N-(2-tert-Butylpyrimidin-5-yl)-3-(3...) Show SMILES CC(C)(C)c1ncc(NC(=O)CCc2nc(no2)-c2ccc(F)cc2Cl)cn1 Show InChI InChI=1S/C19H19ClFN5O2/c1-19(2,3)18-22-9-12(10-23-18)24-15(27)6-7-16-25-17(26-28-16)13-5-4-11(21)8-14(13)20/h4-5,8-10H,6-7H2,1-3H3,(H,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	570	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at rat recombinant CB1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP level				J Med Chem 51: 5019-34 (2008) Article DOI: 10.1021/jm800463f BindingDB Entry DOI: 10.7270/Q2W096VS
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50272345 (CHEMBL499059 | N-(2-tert-Butylpyrimidin-5-yl)-3-(3...) Show SMILES CC(C)(C)c1ncc(NC(=O)CCc2nc(no2)-c2ccc(F)cc2Cl)cn1 Show InChI InChI=1S/C19H19ClFN5O2/c1-19(2,3)18-22-9-12(10-23-18)24-15(27)6-7-16-25-17(26-28-16)13-5-4-11(21)8-14(13)20/h4-5,8-10H,6-7H2,1-3H3,(H,24,27)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human recombinant CB1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP level				J Med Chem 51: 5019-34 (2008) Article DOI: 10.1021/jm800463f BindingDB Entry DOI: 10.7270/Q2W096VS
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50272345 (CHEMBL499059 | N-(2-tert-Butylpyrimidin-5-yl)-3-(3...) Show SMILES CC(C)(C)c1ncc(NC(=O)CCc2nc(no2)-c2ccc(F)cc2Cl)cn1 Show InChI InChI=1S/C19H19ClFN5O2/c1-19(2,3)18-22-9-12(10-23-18)24-15(27)6-7-16-25-17(26-28-16)13-5-4-11(21)8-14(13)20/h4-5,8-10H,6-7H2,1-3H3,(H,24,27)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human CB1 receptor expressed in Sf9 cells by GTP-europium binding assay				J Med Chem 51: 5019-34 (2008) Article DOI: 10.1021/jm800463f BindingDB Entry DOI: 10.7270/Q2W096VS
					More data for this Ligand-Target Pair