Compile Data Set for Download or QSAR

Found 6 hits of ec50 for monomerid = 50272347   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50272347 (5-(3-(3-(2-Chloro-4-fluorophenyl)-1,2,4-oxadiazol-...) Show SMILES Fc1ccc(-c2noc(CCCNc3cnc(OCC(F)(F)F)c(c3)C#N)n2)c(Cl)c1 Show InChI InChI=1S/C19H14ClF4N5O2/c20-15-7-12(21)3-4-14(15)17-28-16(31-29-17)2-1-5-26-13-6-11(8-25)18(27-9-13)30-10-19(22,23)24/h3-4,6-7,9,26H,1-2,5,10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	31	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human recombinant CB2 receptor expressed in Sf9 cells by GTP-europium binding assay				J Med Chem 51: 5019-34 (2008) Article DOI: 10.1021/jm800463f BindingDB Entry DOI: 10.7270/Q2W096VS
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Rattus norvegicus (Rat))	BDBM50272347 (5-(3-(3-(2-Chloro-4-fluorophenyl)-1,2,4-oxadiazol-...) Show SMILES Fc1ccc(-c2noc(CCCNc3cnc(OCC(F)(F)F)c(c3)C#N)n2)c(Cl)c1 Show InChI InChI=1S/C19H14ClF4N5O2/c20-15-7-12(21)3-4-14(15)17-28-16(31-29-17)2-1-5-26-13-6-11(8-25)18(27-9-13)30-10-19(22,23)24/h3-4,6-7,9,26H,1-2,5,10H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	130	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at rat recombinant CB2 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP level				J Med Chem 51: 5019-34 (2008) Article DOI: 10.1021/jm800463f BindingDB Entry DOI: 10.7270/Q2W096VS
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50272347 (5-(3-(3-(2-Chloro-4-fluorophenyl)-1,2,4-oxadiazol-...) Show SMILES Fc1ccc(-c2noc(CCCNc3cnc(OCC(F)(F)F)c(c3)C#N)n2)c(Cl)c1 Show InChI InChI=1S/C19H14ClF4N5O2/c20-15-7-12(21)3-4-14(15)17-28-16(31-29-17)2-1-5-26-13-6-11(8-25)18(27-9-13)30-10-19(22,23)24/h3-4,6-7,9,26H,1-2,5,10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	360	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human recombinant CB2 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP level				J Med Chem 51: 5019-34 (2008) Article DOI: 10.1021/jm800463f BindingDB Entry DOI: 10.7270/Q2W096VS
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50272347 (5-(3-(3-(2-Chloro-4-fluorophenyl)-1,2,4-oxadiazol-...) Show SMILES Fc1ccc(-c2noc(CCCNc3cnc(OCC(F)(F)F)c(c3)C#N)n2)c(Cl)c1 Show InChI InChI=1S/C19H14ClF4N5O2/c20-15-7-12(21)3-4-14(15)17-28-16(31-29-17)2-1-5-26-13-6-11(8-25)18(27-9-13)30-10-19(22,23)24/h3-4,6-7,9,26H,1-2,5,10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at rat recombinant CB1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP level				J Med Chem 51: 5019-34 (2008) Article DOI: 10.1021/jm800463f BindingDB Entry DOI: 10.7270/Q2W096VS
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50272347 (5-(3-(3-(2-Chloro-4-fluorophenyl)-1,2,4-oxadiazol-...) Show SMILES Fc1ccc(-c2noc(CCCNc3cnc(OCC(F)(F)F)c(c3)C#N)n2)c(Cl)c1 Show InChI InChI=1S/C19H14ClF4N5O2/c20-15-7-12(21)3-4-14(15)17-28-16(31-29-17)2-1-5-26-13-6-11(8-25)18(27-9-13)30-10-19(22,23)24/h3-4,6-7,9,26H,1-2,5,10H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human recombinant CB1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP level				J Med Chem 51: 5019-34 (2008) Article DOI: 10.1021/jm800463f BindingDB Entry DOI: 10.7270/Q2W096VS
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50272347 (5-(3-(3-(2-Chloro-4-fluorophenyl)-1,2,4-oxadiazol-...) Show SMILES Fc1ccc(-c2noc(CCCNc3cnc(OCC(F)(F)F)c(c3)C#N)n2)c(Cl)c1 Show InChI InChI=1S/C19H14ClF4N5O2/c20-15-7-12(21)3-4-14(15)17-28-16(31-29-17)2-1-5-26-13-6-11(8-25)18(27-9-13)30-10-19(22,23)24/h3-4,6-7,9,26H,1-2,5,10H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human CB1 receptor expressed in Sf9 cells by GTP-europium binding assay				J Med Chem 51: 5019-34 (2008) Article DOI: 10.1021/jm800463f BindingDB Entry DOI: 10.7270/Q2W096VS
					More data for this Ligand-Target Pair